Zobrazeno 1 - 10
of 126
pro vyhledávání: '"J. L. Platt"'
Autor:
M. Cascalho, D. Huynh, A. R. Lefferts, L. Stein, T. Lanigan, J. Decker, L. D. Shea, J. L. Platt
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-6 (2018)
Abstract Transfer to and enduring expression of genes in B cells has proved a vexing challenge. We report here a novel method for the specific and durable targeting of B lymphocytes in living mice. The method involves generation of lentiviruses pseud
Externí odkaz:
https://doaj.org/article/a8d8bc5a0ace45508e8d50d4287059cd
Publikováno v:
The Journal of Immunology. 157:5163-5168
The most abundant natural IgG Abs in human serum are thought to be Abs specific for Gal alpha1-3Gal, a carbohydrate expressed in lower mammals. IgG Abs specific for Gal alpha1-3Gal have been postulated to contribute to host defense and to participate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f465d05ee28bc361ee73b09509f0b6b
https://doi.org/10.4049/jimmunol.157.11.5163
https://doi.org/10.4049/jimmunol.157.11.5163
Autor:
Z E Holzknecht, J L Platt
Publikováno v:
The Journal of Immunology. 154:4565-4575
Rejection of an organ transplanted into a phylogenetically disparate recipient may be initiated by the binding of xenoreactive natural Abs of the recipient to Ags expressed on donor endothelium leading to the activation of the C system. Having previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17091927f820c1cfa40c7740a0c74856
https://doi.org/10.4049/jimmunol.154.9.4565
https://doi.org/10.4049/jimmunol.154.9.4565
Publikováno v:
Clinical and Experimental Immunology. 86:31-35
SUMMARY We review our studies on the role of complement (C) as mediator of xenograft hyperacute rejection using an in vitro model consisting of porcine endothelial cells as target and human serum as source of natural antibodies and C. Cytotoxicity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::407728be0422ae592f3c7e732bd940a3
https://doi.org/10.1111/j.1365-2249.1991.tb06204.x
https://doi.org/10.1111/j.1365-2249.1991.tb06204.x
Publikováno v:
The FASEB Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a97e5cf0276df4d3e42a79f1bc83c307
https://doi.org/10.1096/fj.06-06-7907com
https://doi.org/10.1096/fj.06-06-7907com
Publikováno v:
Evolution; international journal of organic evolution. 59(9)
Microbes and other organisms smaller than one to a few millimeters in size are hypothesized to have global populations, in contrast to the geographically restricted ranges of larger organisms. However, fungi, which routinely have reproductive propagu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2578f5d68c074183def3e08fc79faf5
https://pubmed.ncbi.nlm.nih.gov/16261727
https://pubmed.ncbi.nlm.nih.gov/16261727
Publikováno v:
Transplantation. 72(3)
Platelets exert their normal functions at sites of endothelial disruption by plugging discontinuities in blood vessels and secreting products that promote thrombosis, inflammation, and the healing of wounds. Whether platelets might induce these chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa0cdd8272be321d2057d70c63fa5a9b
https://pubmed.ncbi.nlm.nih.gov/11502984
https://pubmed.ncbi.nlm.nih.gov/11502984
Autor:
W, Parker, K B, Stitzenberg, P B, Yu, V S, Pratt, Y C, Nakamura, L S, Farel, C M, Ward, S S, Lin, M L, Everett, J L, Platt
Publikováno v:
Transplantation. 71(3)
Natural antibodies directed against cell surface carbohydrates are thought to be vital to host defense and to initiate the rejection of xenografts and ABO-incompatible allografts. The biophysical properties underlying the association and dissociation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::45e234877a7538269914e11af2182a1d
https://pubmed.ncbi.nlm.nih.gov/11233908
https://pubmed.ncbi.nlm.nih.gov/11233908
Autor:
S S, Lin, M J, Hanaway, G V, Gonzalez-Stawinski, C L, Lau, W, Parker, R D, Davis, G W, Byrne, L E, Diamond, J S, Logan, J L, Platt
Publikováno v:
Transplantation. 70(12)
A major impediment to the transplanting of porcine organs into humans is the susceptibility of porcine organs to acute vascular rejection, which can destroy a vascularized xenograft over a period of hours to days. Acute vascular rejection of porcine-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6f15cc9f81929446d53dceeb1d4cced5
https://pubmed.ncbi.nlm.nih.gov/11152095
https://pubmed.ncbi.nlm.nih.gov/11152095
Publikováno v:
Transplantation. 69(10)
During renal allograft rejection, expression of MHC class II antigens is up-regulated on the parenchymal cells of the kidney. This up-regulation of MHC class II proteins may stimulate the intragraft alloimmune response by promoting their recognition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac8c9ec33c9b9ad3dece1bd2036ec427
https://pubmed.ncbi.nlm.nih.gov/10852613
https://pubmed.ncbi.nlm.nih.gov/10852613