Zobrazeno 1 - 10
of 53
pro vyhledávání: '"J. L. Mulshine"'
Publikováno v:
Chest. 103:4S-11
Autor:
J K, Field, R A, Smith, S W, Duffy, C D, Berg, R, van Klaveren, C I, Henschke, D, Carbone, P E, Postmus, E, Paci, F R, Hirsch, J L, Mulshine
Publikováno v:
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 1(5)
The Liverpool Statement 2005 was developed at the Fourth International Lung Cancer Molecular Biomarkers Workshop in Liverpool (October 27-29, 2005) and focused on the priorities for the European Union/United States (EU-US) Spiral Computed Tomography
Publikováno v:
Cancer. 89
The current mortality rate for lung cancer exceeds 85%, as it has for the last 3 decades. This statistic reflects the utility of the major diagnostic tool that has been used during this period to diagnose lung cancer: the chest X-ray. The overwhelmin
Autor:
M S, Tockman, J L, Mulshine
Publikováno v:
Chest surgery clinics of North America. 10(4)
These sputum tests offer great promise in determining a molecular diagnosis of lung cancer far in advance of clinical presentation. Any or all of these tests could be incorporated into the routine management of individuals at risk for developing prim
Autor:
D L, Wang, M, Marko, A R, Dahl, K S, Engelke, M E, Placke, A R, Imondi, J L, Mulshine, L M, De Luca
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(9)
Chemopreventive retinoids may be more effective if delivered to the lung epithelium by inhalation. 13-cis-Retinoic acid (13-cis-RA) was comparable to all-trans-retinoic acid (RA) in inducing transglutaminase II (TGase II) in cultured human cells. Inh
Autor:
A R, Dahl, I M, Grossi, D P, Houchens, L J, Scovell, M E, Placke, A R, Imondi, G D, Stoner, L M, De Luca, D, Wang, J L, Mulshine
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(8)
In previously treated head-and-neck cancer patients, p.o. administered isotretinoin (13-cis retinoic acid) reduced the occurrence of second aerodigestive tumors, including lung tumors, but side effects made chronic therapy problematic. We reasoned th
Autor:
S H, Hong, F G, Ondrey, I M, Avis, Z, Chen, E, Loukinova, P F, Cavanaugh, C, Van Waes, J L, Mulshine
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 14(11)
High levels of prostaglandins are produced in human oropharyngeal carcinoma (OPC). Five human OPC cell lines tested expressed both isoforms of cyclooxygenases (COX). The pan-COX inhibitor ketorolac continuously and significantly decreased PGE(2) prod
Autor:
J L, Mulshine
Publikováno v:
Chest. 116
Strategies for the early detection of lung cancer are being investigated in an attempt to improve the poor prognosis associated with the disease. Such approaches, which include the identification of biomarkers for preclinical disease, must be integra
Autor:
A, Chaudhry, J A, Carrasquillo, I L, Avis, N, Shuke, J C, Reynolds, R, Bartholomew, S M, Larson, F, Cuttitta, B E, Johnson, J L, Mulshine
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(11)
Small cell lung cancer (SCLC) cells express and secrete bombesin-like peptides (BLP) that can activate specific receptors that stimulate the growth of these cells. A murine monoclonal antibody, 2A11, which binds to the BLP, gastrin-releasing peptide
Publikováno v:
Cancer research. 59(9)
Arachidonic acid (AA) metabolizing enzymes are emerging as significant mediators of growth stimulation for epithelial cells. The relative contribution of the various family members of AA metabolizing enzymes to epithelial cancer cell growth is not kn