Zobrazeno 1 - 10
of 35
pro vyhledávání: '"J. L. Maddocks"'
Publikováno v:
British journal of clinical pharmacology. 58(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ad9ca4170d35da964d4d83b9aaecdc8c
https://pubmed.ncbi.nlm.nih.gov/15595985
https://pubmed.ncbi.nlm.nih.gov/15595985
Publikováno v:
Journal of medicinal chemistry. 39(14)
Clinical use of the immunosuppressive drug azathioprine is limited by potentially serious toxic effects related to depression of bone marrow function. The immunosuppressive and toxic properties of azathioprine are regarded as being properties of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0f78ec8149cfa897ae5a595f604ea7
https://pubmed.ncbi.nlm.nih.gov/8709098
https://pubmed.ncbi.nlm.nih.gov/8709098
Publikováno v:
The lancet : international edition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63091a3a3e6b2c4883c9aa023b41f84f
https://hdl.handle.net/10067/42360151162165141
https://hdl.handle.net/10067/42360151162165141
Autor:
J. L. Maddocks, J. MacLachlan
Publikováno v:
Lancet (London, England). 338(8774)
A new fluorescent thiol reagent, dansyl-aminophenylmercuric acetate (DAPMA), was applied to the diagnosis of homocystinuria, a disorder which can be associated with vascular disease at an early age. DAPMA was added to urine containing metabisulphite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b544b6a824fd29c09dcb2ee38e04ae
https://pubmed.ncbi.nlm.nih.gov/1681358
https://pubmed.ncbi.nlm.nih.gov/1681358
Autor:
W.M Heckl, J. L. Maddocks
Publikováno v:
The Lancet. 340:600-601
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca9f31f6a3ff9f828b4abad39cbd679a
https://doi.org/10.1016/0140-6736(92)92126-z
https://doi.org/10.1016/0140-6736(92)92126-z
Publikováno v:
British Journal of Cancer
Twelve boys and 10 girls on similar long term remission maintenance treatment for lymphoblastic leukaemia had 79 random assays of their red cell 6 thioguanine nucleotide ( 6TGN ) concentrations performed as an index of cytotoxic activity generated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4551fff69a3998f23bc2b371e3813c
https://doi.org/10.1038/bjc.1984.111
https://doi.org/10.1038/bjc.1984.111
Autor:
S A Al-Safi, J L Maddocks
Publikováno v:
British Journal of Clinical Pharmacology. 19:108-111
Deficiency of the purine salvage enzymes purine nucleoside phosphorylase (PNP) and adenosine deaminase (ADA) are known causes of immunodeficiency. Evidence for inhibition of these enzymes was sought in 16 patients on azathioprine therapy by testing f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab2ae57baf5e65d090db6486fb8ebaa6
https://doi.org/10.1111/j.1365-2125.1985.tb02623.x
https://doi.org/10.1111/j.1365-2125.1985.tb02623.x
Publikováno v:
British Journal of Clinical Pharmacology. 16:359-363
6-Mercaptopurine is extensively used in the treatment of childhood lymphoblastic leukaemia to prolong the duration of remission achieved with other drugs. The response to remission maintenance therapy varies widely. We investigated the relationship b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::572e74934bf8a4cc152446eb9d1d6f58
https://doi.org/10.1111/j.1365-2125.1983.tb02178.x
https://doi.org/10.1111/j.1365-2125.1983.tb02178.x
Autor:
J L Maddocks
Publikováno v:
Thorax. 30:68-71
The absorption of ampicillin from the lungs after intratracheal administration was studied in a healthy human. Doses of 50 mg, 250 mg, and 1,250 mg were given by intratracheal injection, and absorption of ampicillin from the lungs was assessed by mea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e13739d31138442d24b7fdf37472132
https://doi.org/10.1136/thx.30.1.68
https://doi.org/10.1136/thx.30.1.68
Publikováno v:
Journal of Pharmacological Methods. 2:287-294
The five-sixths nephrectomy model for chronic renal failure of McCance and Morrison ( Q J Exp Physiol 41: 365–386 (1956)) has been assessed in male Wistar rats. Twenty eight days after nephrectomy, serum concentrations of urea and creatinine were i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffaf2e96927d3335986dd352ee80170d
https://doi.org/10.1016/0160-5402(79)90021-4
https://doi.org/10.1016/0160-5402(79)90021-4