Zobrazeno 1 - 10
of 29
pro vyhledávání: '"J. L. Humes"'
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 283(3)
Elastases in cystic fibrosis (CF) pulmonary fluids damage lung tissue and perpetuate cycles of infection, inflammation and injury. Elastases from three different sources may be present in CF airways: neutrophils, macrophages and Pseudomonas. We measu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4ffbc6560d119cf9f3eab03695e5803
https://pubmed.ncbi.nlm.nih.gov/9399994
https://pubmed.ncbi.nlm.nih.gov/9399994
Publikováno v:
Biochemical pharmacology. 49(10)
Incubation of human blood with the secretagogue A23187 resulted in the formation of increased plasma concentrations of polymorphonuclear leukocyte (PMN) elastase: alpha 1 proteinase inhibitor (PMNE:alpha 1 PI) complex as well as A alpha(1-21) fibrino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e1f18fa669848f11249116690c9af812
https://pubmed.ncbi.nlm.nih.gov/7763294
https://pubmed.ncbi.nlm.nih.gov/7763294
Publikováno v:
The International journal of artificial organs. 15(3)
To assess the inter-relationship of leucopenia and PMN elastase release we undertook a prospective crossover study of 6 patients dialysed with new and reused cuprophane, cellulose acetate and polysulfone membranes. Serial blood samples were analysed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1623309af94dcf010fa5a0a4f7b83e4
https://pubmed.ncbi.nlm.nih.gov/1521897
https://pubmed.ncbi.nlm.nih.gov/1521897
Publikováno v:
The Journal of Immunology. 124:2110-2116
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26cb950b70122ec496728acfdc335650
https://doi.org/10.4049/jimmunol.124.5.2110
https://doi.org/10.4049/jimmunol.124.5.2110
Autor:
D D Wood, E K Bayne, M B Goldring, M Gowen, D Hamerman, J L Humes, E J Ihrie, P E Lipsky, M J Staruch
Publikováno v:
The Journal of Immunology. 134:895-903
The supernatants of human monocytes incubated with endotoxin are able to stimulate the proliferation of murine thymocytes in the presence of PHA. This is known as LAF (lymphocyte activating factor) activity and is a characteristic activity of interle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef8730cbc42b3d91583650e4b7706ea4
https://doi.org/10.4049/jimmunol.134.2.895
https://doi.org/10.4049/jimmunol.134.2.895
Publikováno v:
British Journal of Dermatology. 120:49-58
Homogenates of normal human epidermis synthesized 12-hydroxyeicosatetraenoic acid (12-HETE) when incubated in vitro with arachidonic acid. The stereoconfigurations of the C-12 hydroxyl isomers were determined by incubation with potato 5-lipoxygenase.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d53800973ca7e65fad6f93dbd0488149
https://doi.org/10.1111/j.1365-2133.1989.tb07765.x
https://doi.org/10.1111/j.1365-2133.1989.tb07765.x
Autor:
W L Farrar, J L Humes
Publikováno v:
The Journal of Immunology. 135:1153-1159
Several investigations have suggested that products of arachidonic acid metabolism have modulatory effects on the development of cellular immunity. In this report we have studied the role of arachidonic acid metabolism in the specific effects of inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e75db7a0aef25b95b243fcef44aef64d
https://doi.org/10.4049/jimmunol.135.2.1153
https://doi.org/10.4049/jimmunol.135.2.1153
Autor:
E. S. Luedke, J. L. Humes
Publikováno v:
Agents and Actions. 27:451-454
Tumor necrosis factor (rTNF) has previously been shown to induce PMN chemotaxis, stimulate PMN adhesion to vascular endothelium and stimulate hydrogen peroxide secretion from PMNs adhered to biological surfaces. We investigated the activity of both r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3355e7f934e890c6752d29050c29a06
https://doi.org/10.1007/bf01972850
https://doi.org/10.1007/bf01972850
Autor:
F. A. Kuehl, J. L. Humes
Publikováno v:
Proceedings of the National Academy of Sciences. 69:480-484
A prostaglandin receptor is present in rat adipocytes, as shown by competition studies with [ 3 H]-prostaglandin E 1 . The affinity of the E prostaglandins for this receptor preparation is greater than that of A and F prostaglandins, an observation c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee9f8b7e94465b2b610315a187e35275
https://doi.org/10.1073/pnas.69.2.480
https://doi.org/10.1073/pnas.69.2.480
Publikováno v:
Nature. 265(5590)
SINCE the discovery that non-steroidal anti-inflammatory agents (NSAI) are potent inhibitors of prostaglandin synthetase1–3, there has been controversy about the role of primary prostaglandins (PGEs+PGFs=PGs) in inflammatory diseases. A parallel ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39c104859aee8101ca945cb81a7dc75
https://pubmed.ncbi.nlm.nih.gov/834259
https://pubmed.ncbi.nlm.nih.gov/834259