Zobrazeno 1 - 10
of 11
pro vyhledávání: '"J. L. Fernández-Luna"'
Autor:
A. Oterino, José Berciano, C. Fernandez-Viadero, N. Pena, J. Miró, M. Delgado, J. L. Fernández-Luna, C. Leno, Onofre Combarros
Publikováno v:
Acta Neurologica Scandinavica. 97:68-71
INTRODUCTION The role of gender in Alzheimer's disease (AD), and its possible interaction with apolipoprotein E (apoE), has been controversial. MATERIAL AND METHODS ApoE allelic frequencies and the effect of apoE epsilon4 allele dosage on risk and ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f583fd5daec13acd41226528821d5d8f
https://doi.org/10.1111/j.1600-0404.1998.tb00611.x
https://doi.org/10.1111/j.1600-0404.1998.tb00611.x
Autor:
J. L. Fernández-Luna
Publikováno v:
Clinical and Translational Oncology. 9:555-562
Apoptosis serves to remove excess or damaged cells and its dysregulation may lead to a number of pathological disorders including cancer. Studies during the last 20 years have unravelled much of the molecular mechanisms that control apoptosis. Whethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b148d451751b0d8d77a130f031df77
https://doi.org/10.1007/s12094-007-0103-7
https://doi.org/10.1007/s12094-007-0103-7
Publikováno v:
European journal of neurology. 4(2)
We report a family in which expansion of CTG repeats was detected in asymptomatic carriers of the myotonic dystrophy allele in three successive generations. PCR-based analysis of the expanded CTG repeat revealed intergenerational amplification of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956827f69e71dbd738624743c666d88a
https://pubmed.ncbi.nlm.nih.gov/24283914
https://pubmed.ncbi.nlm.nih.gov/24283914
Autor:
F, Mollinedo, J L, Fernández-Luna, C, Gajate, B, Martín-Martín, A, Benito, R, Martínez-Dalmau, M, Modolell
Publikováno v:
Cancer research. 57(7)
The ether lipid 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (ET-18-OCH3; Edelfosine) has been shown to be a rapid inducer of apoptosis in human leukemic cells and has been considered as a promising drug in cancer treatment. Here we have fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf82abba4a347711924271553866b759
https://pubmed.ncbi.nlm.nih.gov/9102220
https://pubmed.ncbi.nlm.nih.gov/9102220
Publikováno v:
Neurology. 63:1135-1136
A chronic inflammatory process might contribute to the neurodegeneration associated with Alzheimer disease (AD), through overexpression of cytokines and other inflammatory molecules in activated microglia surrounding senile plaques.1 The balance betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7475907e143ab330da4959d7d9efd06f
https://doi.org/10.1212/01.wnl.0000138570.96291.a8
https://doi.org/10.1212/01.wnl.0000138570.96291.a8
Publikováno v:
Molecular medicine (Cambridge, Mass.). 1(6)
BACKGROUND: Hereditary angioneurotic edema (HANE) is an autosomal dominant disease due to genetic alterations at the C1 inhibitor gene. Mutations within the C1 inhibitor gene are responsible for the molecular defect in type II HANE. Most of the dysfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::228dd4844290067d0df8491c2d07933e
https://pubmed.ncbi.nlm.nih.gov/8529136
https://pubmed.ncbi.nlm.nih.gov/8529136
Publikováno v:
Journal of endocrinological investigation. 18(3)
Bone remodelling is regulated at the local level by an incompletely elucidated cytokine network. In the present study we have determined the effect of interleukin-4 (IL-4), a cytokine produced by T lymphocytes and other cells, on the activity of muri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed6524297d8845de264ed5ffa1d7976a
https://pubmed.ncbi.nlm.nih.gov/7542294
https://pubmed.ncbi.nlm.nih.gov/7542294
Publikováno v:
The American journal of pathology. 146(2)
Polymorphonuclear leukocytes are generated by differentiation of early myeloid precursors. Once fully differentiated, blood neutrophils are programmed to die rapidly and are removed by tissue macrophages. In normal myeloid cells, the death mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a8c5ce28c4170f6ef0ab0a2e0ba664f
https://pubmed.ncbi.nlm.nih.gov/7856757
https://pubmed.ncbi.nlm.nih.gov/7856757
Publikováno v:
Proceedings of the National Academy of Sciences. 83:1472-1475
Protein HC, a heterogeneously charged low molecular weight glycoprotein, and its IgA complex were isolated from human plasma and urine. Plasma from individuals with monoclonal IgA populations was used as starting material for the isolation of the pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b4620d82644f349930cb67c219195e
https://doi.org/10.1073/pnas.83.5.1472
https://doi.org/10.1073/pnas.83.5.1472