Výsledky vyhledávání - "J. L. Diaz Perez"

Terfenadine-induced apoptosis in human melanoma cells is mediated through Ca2+ homeostasis modulation and tyrosine kinase activity, independently of H1 histamine receptors

Autor: Idoia Ortega-Martínez, Yoana Arroyo-Berdugo, María Dolores Boyano, M. Begoña Ruiz-Larrea, Shawkat-Muhialdin Jangi, J. L. Diaz-Perez, Francesca Nicolau-Galmés, Noelia Andollo

Publikováno v: Carcinogenesis. 29:500-509

In our previous works, we have demonstrated that terfenadine (TEF) induces DNA damage and apoptosis in human melanoma cell lines. In this present work, we have studied the effect of histamine on viability of A375 human melanoma cells and the cell-sig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e9a12f175b0593849927d0155570fe
https://doi.org/10.1093/carcin/bgm292

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Soluble interleukin-2 receptor, intercellular adhesion molecule-1 and interleukin-10 serum levels in patients with melanoma

Autor: M.D. García-Vázquez, T López-Michelena, A. García de Galdeano, R. Izu, J. L. Diaz-Perez, M L Cañavate, Jesús Gardeazabal, J Bilbao, J.A. Raton, María Dolores Boyano, L Díaz-Ramón

Publikováno v: British Journal of Cancer

Serum soluble interleukin-2 receptor (sIL-2R), intercellular adhesion molecule-1 (sICAM-1) and interleukin-10 (IL-10) have each been reported as useful markers for melanoma progression. To evaluate the clinical relevance of these three markers, we si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab5a2731f1ba439ec1a000e934a92a03
https://doi.org/10.1054/bjoc.2000.1402

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Cutaneous metastases of hepatocellular carcinoma

Autor: M, Lazaro, M L, Serrano, I, Allende, J A, Ratón, E, Acebo, J L, Diaz-Perez

Publikováno v: Clinical and Experimental Dermatology. 34:e567-e569

Summary Cutaneous metastases are an unusual finding that may present as the first sign of an internal neoplasia. A case of cutaneous metastases of hepatocellular carcinoma, which may often involve other organs but very rarely metastases to the skin,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e1d2bbca663739dccf2a8d8bdeac28
https://doi.org/10.1111/j.1365-2230.2009.03245.x

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A randomized controlled trial of acyclovir versus netivudine for treatment of herpes zoster. International Zoster Study Group

Autor: S Tyring, S Shukla, M W McKendrick, P L Andersen, J Söltz-Szöts, R F Lucht, A P Fiddian, J L Diaz Perez

Publikováno v: Journal of Antimicrobial Chemotherapy. 41:549-556

Oral acyclovir has become the standard of care for treatment of acute herpes zoster. Netivudine is a novel antiviral with greater in-vitro activity against varicella zoster virus. It was compared with acyclovir in a randomized, double-blind, controll

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30aeed3fb68a159e2a4cc2e2857f1ebe
https://doi.org/10.1093/jac/41.5.549

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Serum-Soluble IL-2 Receptor and IL-6 Levels in Patients with Melanoma

Autor: Isabel Smith-Zubiaga, J. L. Diaz-Perez, M.D. García-Vázquez, A. García de Galdeano, M L Cañavate, Jesús Gardeazabal, I. Bilbao, María Dolores Boyano, J.A. Raton

Publikováno v: Europe PubMed Central

Elevated soluble IL-2 receptor (sIL-2R) and IL-6 serum concentrations have been reported as adverse prognostic factors in several types of cancer. In order to determine whether these factors are predictive of metastatic progression in melanoma, sIL-2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a795792cc6671c09d8116014c789260
https://doi.org/10.1159/000227726

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A Customized Pigmentation SNP Array Identifies a Novel SNP Associated with Melanoma Predisposition in the SLC45A2 Gene

Publikováno v: Addi. Archivo Digital para la Docencia y la Investigación
instname
PLoS One
r-FISABIO. Repositorio Institucional de Producción Científica
PLoS ONE, Vol 6, Iss 4, p e19271 (2011)
PLoS ONE
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)

10 p. As the incidence of Malignant Melanoma (MM) reflects an interaction between skin colour and UV exposure, variations in genes implicated in pigmentation and tanning response to UV may be associated with susceptibility to MM. In this study, 363 S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b92795914c2f584aa641a1c1bee862ca
http://hdl.handle.net/10810/2673

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Bexarotene activates the p53/p73 pathway in human cutaneous T-cell lymphoma

Autor: Aintzane Asumendi, Aintzane Apraiz, María Dolores Boyano, Naiara Nieto-Rementeria, R. Izu, J. L. Diaz-Perez, Gorka Pérez-Yarza

Publikováno v: The British journal of dermatology. 160(3)

Summary Background Bexarotene is the first synthetic retinoid X receptor-selective retinoid (rexinoid) approved for the treatment of cutaneous T-cell lymphoma (CTCL). However, little is known about the signalling pathways by which it exerts its antic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd9132c18434e9be367d1915d975ead
https://pubmed.ncbi.nlm.nih.gov/19067706

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H1 histamine receptor antagonists induce genotoxic and caspase-2-dependent apoptosis in human melanoma cells

Autor: Gorka Pérez-Yarza, María Dolores Boyano, José Luis Díaz-Ramón, Aintzane Asumendi, Shawkat-Muhialdin Jangi, J. L. Diaz-Perez, Jesús Gardeazabal, Itziar Martín-Ruiz, Borja Ochoa-Lizarralde

Publikováno v: Carcinogenesis. 27(9)

Previously, we found that the H1 histamine receptor antagonist diphenhydramine induces apoptosis in human acute T-lymphocytic leukemia cells. Since histamine has been shown to act as a growth factor in malignant melanoma cells, we decided to evaluate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf414f2268de4d334b7bf982d0f27bc
https://pubmed.ncbi.nlm.nih.gov/16569656

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