Zobrazeno 1 - 10
of 234
pro vyhledávání: '"J. Kriegel"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Peritoneal dialysis (PD) is associated with increased cardiovascular (CV) risk. Studies of PD-related CV pathology in animal models are lacking despite the clinical importance. Here we introduce the phenotypic evaluation of a rat model of ca
Externí odkaz:
https://doaj.org/article/f2340f947aae45e2ad5a933d8662f3a9
Autor:
Daria V. Ilatovskaya, Vladislav Levchenko, Kristen Winsor, Gregory R. Blass, Denisha R. Spires, Elizaveta Sarsenova, Iuliia Polina, Adrian Zietara, Mark Paterson, Alison J. Kriegel, Alexander Staruschenko
Publikováno v:
JCI Insight, Vol 7, Iss 9 (2022)
Atrial natriuretic peptide (ANP), encoded by Nppa, is a vasodilatory hormone that promotes salt excretion. Genome-wide association studies identified Nppa as a causative factor of blood pressure development, and in humans, ANP levels were suggested a
Externí odkaz:
https://doaj.org/article/74c5ab87de0b4193aa9e8edabadba11b
Autor:
Eman Y. Gohar, Carmen De Miguel, Ijeoma E. Obi, Elizabeth M. Daugherty, Kelly A. Hyndman, Bryan K. Becker, Chunhua Jin, Randee Sedaka, Jermaine G. Johnston, Pengyuan Liu, Joshua S. Speed, Tanecia Mitchell, Alison J. Kriegel, Jennifer S. Pollock, David M. Pollock
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 5 (2022)
Background Premenopausal women are less likely to develop hypertension and salt‐related complications than are men, yet the impact of sex on mechanisms regulating Na+ homeostasis during dietary salt challenges is poorly defined. Here, we determined
Externí odkaz:
https://doaj.org/article/0cb3e71087914936a984fb5185dc2cdf
Publikováno v:
Non-Coding RNA, Vol 9, Iss 2, p 24 (2023)
Acute kidney injury (AKI) is the rapid reduction in renal function. It is often difficult to detect at an early stage. Biofluid microRNAs (miRs) have been proposed as novel biomarkers due to their regulatory role in renal pathophysiology. The goal of
Externí odkaz:
https://doaj.org/article/79651adb2d244d139cb87158c73f872d
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Novel iron-based shape memory alloys could be candidates for large-scale structural applications if their grains grew large and long enough. Here, the authors add titanium to an Fe–Mn–Al–Ni shape-memory alloy to promote large grains via composi
Externí odkaz:
https://doaj.org/article/17bb895d975744b9a340c0fbc837991b
Autor:
Daria V. Ilatovskaya, Vladislav Levchenko, Tengis S. Pavlov, Elena Isaeva, Christine A. Klemens, Jessica Johnson, Pengyuan Liu, Alison J. Kriegel, Alexander Staruschenko
Publikováno v:
EBioMedicine, Vol 40, Iss , Pp 663-674 (2019)
Background: Autosomal Recessive Polycystic Kidney Disease (ARPKD) is marked by cyst formation in the renal tubules, primarily in the collecting duct (CD) system, ultimately leading to end-stage renal disease. Patients with PKD are generally advised t
Externí odkaz:
https://doaj.org/article/743d1b4485614dc29bb78db2d23142d3
Autor:
David M. Jensen, Peng Han, Lingegowda S. Mangala, Gabriel Lopez-Berestein, Anil K. Sood, Jing Liu, Alison J. Kriegel, Kristie Usa, Michael E. Widlansky, Mingyu Liang
Publikováno v:
Molecular Therapy. 30:3462-3476
MicroRNA miR-29 promotes endothelial function in human arterioles in part by targeting LYPLA1 and increasing nitric oxide production. In addition, miR-29 is a master inhibitor of extracellular matrix gene expression, which may attenuate fibrosis but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83bffd3249f856d528d7d293bb18bd06
https://doi.org/10.1016/j.ymthe.2022.08.007
https://doi.org/10.1016/j.ymthe.2022.08.007
Autor:
Michael E Widlansky, David M Jensen, Jingli Wang, Yong Liu, Aron M Geurts, Alison J Kriegel, Pengyuan Liu, Rong Ying, Guangyuan Zhang, Marc Casati, Chen Chu, Mobin Malik, Amberly Branum, Michael J Tanner, Sudhi Tyagi, Kristie Usa, Mingyu Liang
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 3, Pp 1-14 (2018)
Abstract We investigated the role of microRNAs (miRNA) in endothelial dysfunction in the setting of cardiometabolic disorders represented by type 2 diabetes mellitus (T2DM). miR‐29 was dysregulated in resistance arterioles obtained by biopsy in T2D
Externí odkaz:
https://doaj.org/article/952f272fb18645b9b1998da60a033318
Akademický článek
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Autor:
Devashis, Mukherjee, Ujala, Rana, Alison J, Kriegel, Pengyuan, Liu, Teresa, Michalkiewicz, Girija Ganesh, Konduri
Publikováno v:
Pediatric Research. 93:551-558
Persistent pulmonary hypertension of the newborn (PPHN) occurs when pulmonary vascular resistance (PVR) fails to decrease at birth. Decreased angiogenesis in the lung contributes to the persistence of high PVR at birth. MicroRNAs (miRNAs) regulate ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69851d05e67158d3f82e80303cc89624
https://doi.org/10.1038/s41390-022-02151-3
https://doi.org/10.1038/s41390-022-02151-3