Zobrazeno 1 - 10
of 145
pro vyhledávání: '"J. Kobie"'
Autor:
Michael S. Piepenbrink, Ahmed Magdy Khalil, Ana Chang, Ahmed Mostafa, Madhubanti Basu, Sanghita Sarkar, Simran Panjwani, Yaelyn H. Ha, Yao Ma, Chengjin Ye, Qian Wang, Todd J. Green, James L. Kizziah, Nathaniel B. Erdmann, Paul A. Goepfert, Lihong Liu, David D. Ho, Luis Martinez-Sobrido, Mark R. Walter, James J. Kobie
Publikováno v:
npj Viruses, Vol 2, Iss 1, Pp 1-10 (2024)
Abstract SARS-CoV-2 continues to be a public health burden, driven in-part by its continued antigenic diversification and resulting emergence of new variants. By increasing herd immunity, current vaccines have improved infection outcomes for many. Ho
Externí odkaz:
https://doaj.org/article/fc93c8dbfeef47ec8f5ad7779811e16c
Autor:
Tim R. Mosmann, Jonathan A. Rebhahn, Stephen C. De Rosa, Michael C. Keefer, M. Juliana McElrath, Nadine G. Rouphael, Giuseppe Pantaleo, Peter B. Gilbert, Lawrence Corey, James J. Kobie, Juilee Thakar
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe HVTN 105 vaccine clinical trial tested four combinations of two immunogens - the DNA vaccine DNA-HIV-PT123, and the protein vaccine AIDSVAX B/E. All combinations induced substantial antibody and CD4+ T cell responses in many participa
Externí odkaz:
https://doaj.org/article/52dd5afd41534ef9921ac84b943b0929
Autor:
Michael Piepenbrink, Fatai Oladunni, Aitor Nogales, Ahmed M. Khalil, Theresa Fitzgerald, Thomas A. Hilimire, Madhubanti Basu, Christopher Fucile, David J. Topham, Alexander F. Rosenberg, Luis Martinez-Sobrido, James J. Kobie
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/3c461e3578174133b041510e0c25377b
Autor:
Daniel N. Streblow, Alec J. Hirsch, Jeffrey J. Stanton, Anne D. Lewis, Lois Colgin, Ann J. Hessell, Craig N. Kreklywich, Jessica L. Smith, William F. Sutton, David Chauvin, Jennifer Woo, Benjamin N. Bimber, Cierra N. LeBlanc, Sonia N. Acharya, Brian J. O’Roak, Harjinder Sardar, Mohammad M. Sajadi, Zahra R. Tehrani, Mark R. Walter, Luis Martinez-Sobrido, James J. Kobie, Rachel J. Reader, Katherine J. Olstad, Theodore R. Hobbs, Erica Ollmann Saphire, Sharon L. Schendel, Robert H. Carnahan, Jonas Knoch, Luis M. Branco, James E. Crowe, Koen K. A. Van Rompay, Phillip Lovalenti, Vu Truong, Donald N. Forthal, Nancy L. Haigwood
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Passively administered monoclonal antibodies (mAbs) given before or after viral infection can prevent or blunt disease. Here, we examine the efficacy of aerosol mAb delivery to prevent infection and disease in rhesus macaques inoculated with
Externí odkaz:
https://doaj.org/article/8766bd1dd34746b3b375ff5406037cd7
Autor:
Sanghita Sarkar, Dave D. Hill, Alexander F. Rosenberg, Ellen F. Eaton, Olaf Kutsch, James J. Kobie
Publikováno v:
Cells, Vol 13, Iss 12, p 1011 (2024)
The opioid epidemic continues to be a major public health issue that includes millions of people who inject drugs (PWID). PWID have increased incidence of serious infections, including HIV as well as metabolic and inflammatory sequelae. We sought to
Externí odkaz:
https://doaj.org/article/5041e70a560640e49b4487438476f987
Autor:
Michael Piepenbrink, Fatai Oladunni, Aitor Nogales, Ahmed M. Khalil, Theresa Fitzgerald, Madhubanti Basu, Christopher Fucile, David J. Topham, Alexander F. Rosenberg, Luis Martinez-Sobrido, James J. Kobie
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Due to antigenic drift and shift of influenza A viruses (IAV) and the tendency to elicit predominantly strain-specific antibodies, humanity remains susceptible to new strains of seasonal IAV and is at risk from viruses with pandemic potentia
Externí odkaz:
https://doaj.org/article/ebdd68412b794cc08dc6d57fed2668bf
Autor:
Chengjin Ye, Jun-Gyu Park, Kevin Chiem, Piyush Dravid, Anna Allué-Guardia, Andreu Garcia-Vilanova, Paula Pino Tamayo, Vinay Shivanna, Amit Kapoor, Mark R. Walter, James J. Kobie, Richard K. Plemper, Jordi B. Torrelles, Luis Martinez-Sobrido
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to a worldwide coronavirus disease 2019 (COVID-19) pandemic. Despite the high efficacy of the authorized vaccines, there may be uncertain and unknown side effects or disadv
Externí odkaz:
https://doaj.org/article/fabdbacf676945fcb48c369205349169
Autor:
Kevin Chiem, Jun-Gyu Park, Desarey Morales Vasquez, Richard K. Plemper, Jordi B. Torrelles, James J. Kobie, Mark R. Walter, Chengjin Ye, Luis Martinez-Sobrido
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the highly contagious agent responsible for the coronavirus disease 2019 (COVID-19) pandemic. An essential requirement for understanding SARS-CoV-2 biology and the impact of ant
Externí odkaz:
https://doaj.org/article/3cce0d5668f648ada70155997d43f4ff
Autor:
Yunda Huang, Yuanyuan Zhang, Kelly E. Seaton, Stephen De Rosa, Jack Heptinstall, Lindsay N. Carpp, April Kaur Randhawa, Lyle R. McKinnon, Paul McLaren, Edna Viegas, Glenda E. Gray, Gavin Churchyard, Susan P. Buchbinder, Srilatha Edupuganti, Linda-Gail Bekker, Michael C. Keefer, Mina C. Hosseinipour, Paul A. Goepfert, Kristen W. Cohen, Brian D. Williamson, M. Juliana McElrath, Georgia D. Tomaras, Juilee Thakar, James J. Kobie
Publikováno v:
EBioMedicine, Vol 84, Iss , Pp 104271- (2022)
Summary: Background: The identification of baseline host determinants that associate with robust HIV-1 vaccine-induced immune responses could aid HIV-1 vaccine development. We aimed to assess both the collective and relative performance of baseline c
Externí odkaz:
https://doaj.org/article/fadb3c4955a04c03b07eef2fa43a9e8d
Autor:
Ahmed M. Khalil, Michael S. Piepenbrink, Ian Markham, Madhubanti Basu, Luis Martinez-Sobrido, James J. Kobie
Publikováno v:
Viruses, Vol 15, Iss 7, p 1540 (2023)
Influenza B virus (IBV) contributes to substantial influenza-mediated morbidity and mortality, particularly among children. Similar to influenza A viruses (IAV), the hemagglutinin (HA) and neuraminidase (NA) of IBV undergo antigenic drift, necessitat
Externí odkaz:
https://doaj.org/article/d3f2f9e1fdf74bd6a2d3bcea7900c0a2