Zobrazeno 1 - 10
of 281
pro vyhledávání: '"J. Klostergaard"'
Publikováno v:
IEEE Transactions on Magnetics. 49:336-342
Superparamagnetic iron oxide nanoparticles (SPION), carrying a covalently linked chemotherapeutic agent, can be magnetically directed to concentrate at a tumor under the influence of external shaped/focused magnetic field gradients. Following extrava
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad679ba2914796c8f195aa7fd3c67bea
https://doi.org/10.1109/tmag.2012.2230397
https://doi.org/10.1109/tmag.2012.2230397
Publikováno v:
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society. 10(2)
Resistance to chemotherapy commonly compromises the treatment of many advanced cancers. Evidence suggests a correlation between chemoresistance and more aggressive tumor growth, possibly through accumulation of additional genetic defects in drug-trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41413bdbaf43c0f8417eb63bd0af0671
https://pubmed.ncbi.nlm.nih.gov/11240661
https://pubmed.ncbi.nlm.nih.gov/11240661
Publikováno v:
Oncogene. 13(8)
The retinoblastoma gene product, Rb, has previously been implicated as an obligatory component in the antiproliferative effects mediated by the lipid second messenger, ceramide. We have evaluated both the apoptotic effects and the effects on cell cyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a1ba7160b83de6416bac8491b18ce0bc
https://pubmed.ncbi.nlm.nih.gov/8895515
https://pubmed.ncbi.nlm.nih.gov/8895515
Autor:
K, Akimaru, E, Auzenne, Y, Akimaru, M E, Leroux, A C, Hayman, T, Utsumi, G, Soma, J, Klostergaard
Publikováno v:
Cytokines and molecular therapy. 1(3)
The tumor necrosis factor (TNF) mutant TNF-SAM2 has previously been shown to have a therapeutic profile superior to parental TNF. To initially evaluate the characteristics of liposomal formulations of TNF-SAM2, it was modified with the N-hydroxysucci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::68d847d0720425cae2c248a5cde8de94
https://pubmed.ncbi.nlm.nih.gov/9384676
https://pubmed.ncbi.nlm.nih.gov/9384676
Publikováno v:
European Journal of Cancer. 48:38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::504ebc1aff44f8580b4bcb02b924f91b
https://doi.org/10.1016/s0959-8049(12)71920-2
https://doi.org/10.1016/s0959-8049(12)71920-2
Publikováno v:
Lymphokine and cytokine research. 13(2)
Previous studies have implicated ADP-ribosylation in the mechanism of TNF cytotoxicity. In short-term 51Cr-release assays with several mouse and human tumor cell lines, the inhibitors aminobenzamide (ABA) and nicotinamide (NA) of ADP-ribosylation sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::12ce2ddae88c1ff21203e5ae74ad806f
https://pubmed.ncbi.nlm.nih.gov/7914750
https://pubmed.ncbi.nlm.nih.gov/7914750
Autor:
J. Klostergaard, W.S.L. Liao, J. McMurray, P.K. Mandal, M. Shanker, E.J. Auzenne, Ailing W. Scott, R. Ramesh, Z. Lu
Publikováno v:
European Journal of Cancer Supplements. 8:134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a9b6c834a02ee951e5fc2f93a966aee
https://doi.org/10.1016/s1359-6349(10)72129-7
https://doi.org/10.1016/s1359-6349(10)72129-7
Publikováno v:
Cancer research. 52(19)
We have investigated the cytotoxic responses in vitro of three human colon tumor cell lines with epithelial-like morphology, DLD-1, HCT-15, and HT-29, to thermochemoimmunotherapy with hyperthermia (42 degrees C for 2 h), carboplatin, and recombinant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0aca7ffabd9fd9bf1e2567147507a020
https://pubmed.ncbi.nlm.nih.gov/1394131
https://pubmed.ncbi.nlm.nih.gov/1394131
Autor:
S, Ohno, F R, Strebel, L C, Stephens, Z H, Siddik, M, Makino, J, Klostergaard, S P, Tomasovic, A R, Khokhar, J M, Bull
Publikováno v:
Cancer research. 52(15)
This study examined the effect of a trimodality therapy of the combination of recombinant human tumor necrosis factor alpha (TNF), whole-body hypertheria (WBH), and cis-diamminedichloroplatinum(II) (CDDP) or cis-diammine-1,1-cyclobutane dicarboxylate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cfae95c6b3a9dc2894efc88ea9b2acb6
https://pubmed.ncbi.nlm.nih.gov/1638521
https://pubmed.ncbi.nlm.nih.gov/1638521
Publikováno v:
Journal of immunotherapy : official journal of the Society for Biological Therapy. 11(2)
Hyperthermia can strikingly enhance tumor necrosis factor-alpha (TNF-alpha) cytotoxicity in vitro and in vivo. Other forms of TNF may have tumor therapeutic applications and their interaction with hyperthermia should also be assessed. We have compare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::51734ce5e1f7bae70befbf881b6b35ab
https://pubmed.ncbi.nlm.nih.gov/1571335
https://pubmed.ncbi.nlm.nih.gov/1571335