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pro vyhledávání: '"J. Kirchmeier"'
Akademický článek
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Autor:
S. Ries, A. Siever, P. Schicklmaier, M. Liedtke, W. Käfferlein, C. Wernsdörfer, S. Gmünd, J. Fischer, U. Kausch, J. Kirchmeier, A. Richter, G. Niemczyk, H. P. Hartung, K. Gottwald, F. Hoffmann, Norman Putzki, G. Reifschneider
Publikováno v:
European Journal of Neurology. 16:713-720
To examine the quality of life (QoL) in a large cohort of untreated patients with relapsing-remitting multiple sclerosis (RRMS) and to investigate the impact of intramuscular (IM) interferon beta-1a (IFNbeta-1a) treatment.Prospective, observational,
Autor:
Tatsuhiro Ishida, Marc J. Kirchmeier, Toshinari Meguro, John H. Zhang, Yoshihiro Takanashi, Theresa M. Allen
Publikováno v:
Journal of Clinical Neuroscience. 8:557-561
To date, the pharmacological approach to cerebral vasospasm following subarachnoid hemorrhage has been hampered in part by an inability to attain sufficiently high concentrations of vasodilator drugs in the cerebrospinal fluid (CSF). To overcome this
Publikováno v:
Neurologia medico-chirurgica. 41:107-114
Pharmacological treatment for cerebral ischemia cannot attain sufficiently high concentrations of the drugs in the cerebrospinal fluid (CSF) without precipitating systemic side effects. The objective of this study is the development of a liposomal dr
Autor:
Lizzia Raffaghello, Paolo G. Montaldo, Marc J. Kirchmeier, Mirco Ponzoni, Valeria Chiesa, Gabriella Pagnan, Fabio Pastorino, Theresa M. Allen
Publikováno v:
International Journal of Cancer. 81:262-267
Melanoma is a highly malignant and increasingly common tumour. Since metastatic melanoma remains incurable, new treatment approaches are needed. Previously, we reported that the synthetic retinoid N-(4-hydroxyphenyl)retinamide (fenretinide, HPR) indu
Autor:
Gabriella Pagnan, Theresa M. Allen, Paolo G. Montaldo, Fabio Pastorino, Marc J. Kirchmeier, Lizzia Raffaghello, Mirco Ponzoni
Publikováno v:
International Journal of Cancer. 81:268-274
Melanoma is a highly malignant and increasingly common neoplasm. Because metastatic melanoma remains incurable, new treatment approaches are needed. Immunoliposomes have been previously shown to enhance the selective localization of immunoliposome-en
Publikováno v:
Journal of Liposome Research. 9:199-228
We have previously demonstrated that liposomal doxorubicin (DXR), targeted against the CD 19 receptor of human B lymphoma (Namalwa) cells resulted in selective affinity of SIL[anti-CD19] for CD19+ Namalwa cells in vitro and significantly increased th
Autor:
Mirco Ponzoni, Theresa M. Allen, Fabio Pastorino, Gabriella Pagnan, Paolo G. Montaldo, Marc J. Kirchmeier, Lizzia Raffaghello
Publikováno v:
Journal of Liposome Research. 9:367-385
Patients with neuroblastoma (NB) are often refractory to metabolic radiotherapy with radioiodine-labelled metaiodobenzylguanidine (MIBG), generally due to low, if any, expression of the transporter molecule responsible for MIBG uptake in tumor cells.
Publikováno v:
Journal of the American Chemical Society. 118:7663-7666
Dihydroxyacetanilide, 4, is oxidized to the 5R,6S-epoxyquinone, 3, by dihydroxyacetanilide epoxidase-I (DHAE I) from Streptomyces LL-C10037, without the assistance of an organic cofactor. 13C NMR analysis revealed that in the presence of 18O2 a full
Publikováno v:
Journal of liposome research. 11(1)
Previously, we showed that liposomes with surface-attached anti-CD19 were internalized into human B lymphoma cells through receptor-mediated endocytosis, resulting in improved anti-tumor efficacy 1-2 . In order to further increase the efficacy of ant