Zobrazeno 1 - 10
of 16
pro vyhledávání: '"J. Kevin Kerzee"'
Autor:
Mary Beth Genter, Daniel W. Nebert, J. Kevin Kerzee, Nadine Dragin, Jennifer Marlowe, Timothy P. Dalton, Alvaro Puga
Publikováno v:
Biochemical and Biophysical Research Communications. 348:120-123
Naphthalene (NP) has been designated a ‘reasonably anticipated human carcinogen’ because of positive responses in carcinogenicity bioassays in rodents. Whereas CYP2F enzymes are widely regarded as responsible for NP bioactivation, other metabolic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12769325b6e8c968358df69c01988b59
https://doi.org/10.1016/j.bbrc.2006.07.025
https://doi.org/10.1016/j.bbrc.2006.07.025
Autor:
C. Stuart Baxter, Alvaro Puga, Ming-ya Huang, J. Kevin Kerzee, Yu-Dan Wei, Craig R. Tomlinson, Mario Medvedovic, Maureen A. Sartor
Publikováno v:
Cardiovascular Toxicology. 4:385-404
Exposure to environmental toxicants may play a role in the onset and progression of cardiovascular disease. Many environmental agents, such as dioxin, are risk factors for atherosclerosis because they may exacerbate an underlying disease by altering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b694bb62e2007727f402cce6d38ec41e
https://doi.org/10.1385/ct:4:4:385
https://doi.org/10.1385/ct:4:4:385
Autor:
Timothy P. Dalton, Alvaro Puga, Daniel W. Nebert, J. Kevin Kerzee, Shigeyuki Uno, Mary Beth Genter, Richard J. Hutchinson, Albert P. Senft, Howard G. Shertzer
Publikováno v:
Free Radical Biology and Medicine. 33:1268-1278
2,3,7,8-Tetrachlorodibenzo-p-dioxin (dioxin; TCDD) is a pervasive environmental contaminant that induces hepatic and extrahepatic oxidative stress. We have previously shown that dioxin increases mitochondrial respiration-dependent reactive oxygen pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d43696101c20608fe6d100bc79a10c9
https://doi.org/10.1016/s0891-5849(02)01014-6
https://doi.org/10.1016/s0891-5849(02)01014-6
Autor:
Napoleon F. Alejandro, Kenneth S. Ramos, Russell C. Bowes, Christopher M. Bral, Alan R. Parrish, J. Kevin Kerzee
Publikováno v:
Biochemical Pharmacology. 64:31-39
Exposure of cultured glomeruli to benzo[a]pyrene (BaP), a carcinogenic hydrocarbon, modulates mesangial and visceral epithelial cell proliferation in vivo and in vitro. The present studies were conducted to characterize mitogenic signaling profiles o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6db677381b6b232dcd326536277141c
https://doi.org/10.1016/s0006-2952(02)01054-7
https://doi.org/10.1016/s0006-2952(02)01054-7
Autor:
Kenneth S. Ramos, J. Kevin Kerzee
Publikováno v:
Circulation Research. 89:573-582
Abstract— Ahr is a ligand-activated bHLH/PAS transcription factor involved in cytochrome P450 (CYP) gene regulation and murine susceptibility to atherogenic stimuli. The present studies were conducted to examine constitutive and inducible expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e5a63d1035bfd51cf769bff7305236b
https://doi.org/10.1161/hh1901.097083
https://doi.org/10.1161/hh1901.097083
Autor:
J. Kevin Kerzee
Publikováno v:
Cardiovascular Toxicology. 2:161-163
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddb4599a83422db929915c66a575c189
https://doi.org/10.1007/s12012-002-0001-8
https://doi.org/10.1007/s12012-002-0001-8
Publikováno v:
Dioxins and Health, Second Edition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b1c3a9d8e34f619f0cc885a9aac654e
https://doi.org/10.1002/0471722014.ch13
https://doi.org/10.1002/0471722014.ch13
Publikováno v:
An Introduction to Toxicogenomics ISBN: 9780429211089
An Introduction to Toxicogenomics
An Introduction to Toxicogenomics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::801f31f05c4ab06a7414c30d0d9a9500
https://doi.org/10.1201/9780203504819-8
https://doi.org/10.1201/9780203504819-8
Autor:
Xaoqing Chang, Sonya J. Barnes, Matt Strobeck, J. Kevin Kerzee, Zongqing Tan, Alvaro Puga, Erik S. Knudsen, Jennifer Marlowe, Ching-Yi Chang, Andrew Maier
Publikováno v:
Toxicology.
One of the most puzzling aspects of the biological impact of polycyclic aromatic hydrocarbon compounds is that they elicit an apparently unrelated variety of toxic, teratogenic, and carcinogenic responses in exposed animals and in humans. At the cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e686ea0972ea093ba51efd1b1318e19
https://pubmed.ncbi.nlm.nih.gov/12505305
https://pubmed.ncbi.nlm.nih.gov/12505305
Autor:
J. Kevin Kerzee, Kenneth S. Ramos
Publikováno v:
Molecular pharmacology. 58(1)
Repeated cycles of vascular injury by benzo(a)pyrene (BaP) increase the onset and progression of atherosclerotic lesions in laboratory animals. This atherogenic response is partly mediated by activation of cis-acting antioxidant/electrophile response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e4dbb01c95a6488174f5c56dbcacc6
https://pubmed.ncbi.nlm.nih.gov/10860937
https://pubmed.ncbi.nlm.nih.gov/10860937