Zobrazeno 1 - 10
of 99
pro vyhledávání: '"J. Kevin Donahue"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Ventricular arrhythmias after heart attack are a leading cause of death. Here the authors show, in a porcine model, that KCNE3 and KCNE4 upregulation and a unique pattern of repolarization heterogeneity in the scar facilitate reentrant ventricular ta
Externí odkaz:
https://doaj.org/article/b266107708554e1cbe599481b6c4a68b
Autor:
Janet M. Benson, Gensheng Wang, Julie A. Hutt, Guodong Wu, Stephen M. Kaminsky, Sara Cram, Rajeshkumar Barur, J. Kevin Donahue
Publikováno v:
Basic & Clinical Pharmacology & Toxicology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e8a4ecc064650d3a1a46cbb4968e1a6
https://doi.org/10.1111/bcpt.13885
https://doi.org/10.1111/bcpt.13885
Autor:
Weilan, Mo, J Kevin, Donahue
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2573
Gene therapy appears promising as a targeted treatment of cardiac diseases. Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and also a major contributor to stroke, heart failure, and death. Mechanisms that initiate and sustai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::16e6b8e58ff56100a7fb43821ac840fd
https://pubmed.ncbi.nlm.nih.gov/36040597
https://pubmed.ncbi.nlm.nih.gov/36040597
Autor:
David J. Callans, J. Kevin Donahue
Publikováno v:
JACC Clin Electrophysiol
OBJECTIVES: This study was designed to determine whether re-entrant circuits in human post infarction ventricular tachycardia (VT) are associated with repolarization heterogeneity. BACKGROUND: Slow conduction, caused by fibrosis between surviving myo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23956ac57142d89310314fb7b2875978
https://europepmc.org/articles/PMC9236155/
https://europepmc.org/articles/PMC9236155/
Autor:
Weilan Mo, J. Kevin Donahue
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627068
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e03d762c572043c857f96038d1ef4e4c
https://doi.org/10.1007/978-1-0716-2707-5_16
https://doi.org/10.1007/978-1-0716-2707-5_16
Publikováno v:
Heart Rhythm. 16:1080-1088
Background Atrial fibrillation (AF) is sustained by reentrant mechanisms that depend, in part, on atrial structural remodeling. Increased Ca2+/calmodulin-dependent protein kinase II (CaMKII) activity occurs in persistent AF. A general consensus has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60792eb5c87a0f174170ee87b0d91e4
https://doi.org/10.1016/j.hrthm.2019.01.013
https://doi.org/10.1016/j.hrthm.2019.01.013
Autor:
J. Kevin Donahue, David D. McManus
Publikováno v:
Heart Rhythm. 19:S151
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df11d1d8f7bb69d088d3b42440c26a8e
https://doi.org/10.1016/j.hrthm.2022.03.868
https://doi.org/10.1016/j.hrthm.2022.03.868
Autor:
Shankar P. Parajuli, J. Kevin Donahue
Current treatment for ventricular arrhythmias with antiarrhythmic drugs, implantable cardioverter defibrillators, or radiofrequency ablation has limited efficacy and detrimental impact on the quality of life. Gene and cell therapy have promising prec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77906cc4ba30446efa0738e3ff91a57b
https://doi.org/10.1016/b978-0-12-813704-8.00032-2
https://doi.org/10.1016/b978-0-12-813704-8.00032-2
Autor:
Amir AbdelWahab, Kedar K. Aras, Rishi Arora, Latib Azeem, Ronald D. Berger, James C. Blankenship, Gerard J.J. Boink, Davide Bolignano, Dana Boucek, Tobias Brügmann, Doron Bushi, Sheena W. Chen, Vincent M. Christoffels, Michel Corban, Regazzoli Damiano, Debabrata Dash, Robert David, Antoine A.F. de Vries, Harsha D. Devalla, J. Kevin Donahue, Igor R. Efimov, Abdallah El-Sabbagh, Giannini Francesco, Ponticelli Francesco, Paul Friedman, Dirk Geerts, M. Imran Ghare, Kashish Goel, Marie José T.H. Goumans, Robert Gray, Gallone Guglielmo, Stephanie El Hajj, Jacob A Hoffman, David R. Holmes, Jr, Erik W. Holy, Richard P. Jones, II, Johanna P. Laakkonen, Alexandra Lansky, K. Benjamin Lee, Mark S Link, Baldetti Luca, Gramegna Mario, Bernhard Meier, Dr Rohit Mody, Christine L Mummery, Fabian Nietlispach, Udi Nussinovitch, Emile Nyns, Jeffrey S. Panting, Shankar P. Parajuli, Nimesh Patel, Daniël A. Pijnappels, Abhiram Prasad, T. Alexander Quinn, Claire E. Raphael, Elon Reshef, Avi Sabbag, John Sapp, Philipp Sasse, Mark J. Schneider, Hanno L. Tan, Daniela Tirziu, Amar Trivedi, Anna M.D. Végh, Chance Witt, Rose T. Yin, Seppo Ylä-Herttuala, Shanshan Zhou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::049488fd5097a89d1e16ce9f528e0dfe
https://doi.org/10.1016/b978-0-12-813704-8.00050-4
https://doi.org/10.1016/b978-0-12-813704-8.00050-4
Autor:
Kevin C. Floyd, Owusu Asamoah, J. Kevin Donahue, Nisha I. Parikh, Gerard P. Aurigemma, Cynthia Ennis, David D. McManus, Clifford Browning, Adedotun Ogunsua, Amir Y. Shaikh, Glenn Stokken, Matthew Spring, Mayank Sardana, Lawrence Rosenthal
Publikováno v:
Journal of Cardiovascular Electrophysiology. 27:1411-1419
Introduction Although catheter ablation (CA) for atrial fibrillation (AF) is commonly used to improve symptoms, AF recurrence is common and new tools are needed to better inform patient selection for CA. Left Atrial Function Index (LAFI), an echocard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b436b5c90742dd4dbb0bb19745c3d03
https://doi.org/10.1111/jce.13086
https://doi.org/10.1111/jce.13086