Výsledky vyhledávání

Relapse rates and enhancing lesions in a phase II trial of natalizumab in multiple sclerosis

Autor: D. Dodick, K. Bruining, Catherine M. Dalton, W. Morrison, D. Derrington, A. Bowling, J. Adams, J. Hebert, S. Curtis, Minhua Yang, Gareth J. Barker, R. E. Kramer, J. P. Kelly, D. G. MacManus, Shôn Lewis, L. Costley, K. Bracht, E. Drexler, M. Malikowski, R. S. Murray, Clive Hawkins, K. Markopoulou, David P. Richman, William A. Sheremata, K. Nelson, M. Yeung, R. Wolintz, I. Rozentsvit, Joel Oger, Luanne M. Metz, Kathleen Healey, Jonathan L. Carter, Zahid Latif, J. Trotter, C. Mathews, C. Wallace, Jinan Al-Omaishi, Katherine Riester, Todd L. Richards, C. Webb, B. Harwick, Thomas E. Conturo, C. Gibson, E. Prenger, G. Foster, J. Forsyth, Michael Kaufman, L D Blumhardt, D. A H Cross, J. Curlis, James D. Bowen, C. Coombs, V. Orpe, Mark A. Agius, Omar Khan, C. Martinez, J. Takata, C. Graves, S. Putman, J. Scott, A. Diedrich, L. Capolino, J. Leitch, Per Soelberg Sørensen, M. Cochran, M. Buonocore, P. English, Christopher F. O'Brien, M. J. Keilson, A. Schneider, A. Miller, George Rice, Alexandros Tselis, C. Middleditch, S. Dombrowski, L. Wang, H. Oltazewska, J. Lauber, J. Heuser, H. Lew, Virginia Devonshire, M. Zvartau-Hinds, M. Burke, D. Patry, Paul O'Connor, M. Chang, Katherine A. Miszkiel, Lauren Seeberger, David W. Bates, L. Sciarra, E. Riddle, Robert P. Lisak, Michael Panzara, David Miller, R. Follmer, T. Jaspen, M. Din, T. Pepple, Christina Caon

Publikováno v: Multiple Sclerosis Journal. 11:568-572

Background: Natalizumab, a humanized monoclonal IgG4 antibody, is an a4-integrin antagonist, which inhibits the migration of inflammatory cells into the central nervous system, a key pathogenic mechanism in multiple sclerosis (MS). In a six month, ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38665639a011a220df8600c7e84283b2
https://doi.org/10.1191/1352458505ms1205oa

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Elektronická kniha

Markov Chain Models — Rarity and Exponentiality

Autor: J. Keilson

in failure time distributions for systems modeled by finite chains. This introductory chapter attempts to provide an over view of the material and ideas covered. The presentation is loose and fragmentary, and should be read lightly initially. Subse

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Networks of non-homogeneous M/G/∞ systems

Autor: J. Keilson, L. D. Servi

Publikováno v: Journal of Applied Probability. 31:157-168

For a network of G/∞ service facilities, the transient joint distribution of the facility populations is shown by new simple methods to have a simple Poisson product form with simple explicit formulas for the means. In the network it is assumed tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::288c1d32fb503fcd15e00a06d0aede67
https://doi.org/10.2307/3214954

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The matrix M/M/∞ system: retrial models and Markov Modulated sources

Autor: J. Keilson, L. D. Servi

Publikováno v: Advances in Applied Probability. 25:453-471

The matrix-geometric work of Neuts could be viewed as a matrix variant of M/M/1. A 2 × 2 matrix counterpart of Neuts for M/M/∞ is introduced, the stability conditions are identified, and the ergodic solution is solved analytically in terms of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b1612465fa2d329f47417cc3b36143ec
https://doi.org/10.2307/1427662

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