Zobrazeno 1 - 10
of 182
pro vyhledávání: '"J. KUSZMANN"'
Publikováno v:
Die Pharmazie. 59(5)
Two suitable methods for the synthesis of the heparin degradation product 2,5-anyhydro-3-O-(alpha-L-idopyranosyluronate)-D-mannitol hexa O-sulfate are reported. The synthesis pathways start from D-glucose and D-glucosamine.
Autor:
J, Kuszmann
Publikováno v:
Acta pharmaceutica Hungarica. 71(1)
This paper deals with results of the search for anticancer agents achieved at IDR during the period of 1953-1983. This research activity concentrated on the following four topics: 1) biological alkylating agents, 2) nucleoside type antimetabolites, 3
Publikováno v:
Carbohydrate research. 308(3-4)
D-Xylose was converted via 1,2-O-isopropylidene-alpha-D-xylofuranose (4) into 3-O-benzoyl-5-S-benzoyl-1,2-O-isopropylidene-alpha-D-xylofuranose which, after methanolysis, acetylation and subsequent acetolysis afforded 1,2,3,4-tetra-O-acetyl-5-thio-al
Publikováno v:
Carbohydrate research. 311(4)
5-S-Benzoyl-2,3-O-isopropylidene-5-thio-L-arabinose, prepared from L-arabinose diethyl dithioacetal gave, on treatment with sodium methoxide in methanol, 4-O-benzoyl-2,3-O-isopropylidene-5-thio-L-arabinopyranose 12 which was converted into its 1-O-ac
Autor:
J Kuszmann, E Gacsbaitz
Publikováno v:
Australian Journal of Chemistry. 49:273
Benzylidenation of D-arabinose diethyl and dipropyl dithioacetals with α,α-dimethoxytoluene in the presence of p-toluenesulfonic acid has been studied in detail. Under kinetic control the two terminal dioxolan -type 4,5-O-(R)- and 4,5-O-(S)-benzyli
Autor:
É. Tomori, J. Kuszmann
Publikováno v:
Journal of Chromatography A. 299:87-96
Compounds obtained on acetonation of D -mannitol were studied by gas chromatography and gas chromatography-mass spectrometry. The separation of the reaction mixtures was achieved on capillary columns coated with Carbowax 20M or OV-101. Methylene unit
Autor:
J. Kuszmann, P. Sohár
Publikováno v:
Organic Magnetic Resonance. 21:694-697
The structure of 1:3,2:4,5:6-tri-O-isopropylidene-D-glucitol, which was proposed earlier to be the 1:2,3:5,4:6-analogue, was re-detormined by 1H NMR measurement at 250 MHz. The assignments were proved by double resonance experiments. Using the spectr
Autor:
L. Vargha, J. Kuszmann
Publikováno v:
Carbohydrate Research. 17:309-318
The synthesis of 1-bromo-6-chloro-1,6-dideoxy- D -mannitol, 1-bromo-1,6-dideoxy-6-iodo- D -mannitol, 1-bromo-1-deoxy-6- O -methanesulphonyl- D -mannitol 19 , and some of their derivatives, via 5,6-anhydro-2,4- O -benzylidene-1-bromo-1-deoxy- D -manni
Publikováno v:
Biochemical Pharmacology. 11:639-649
Some new 3:4:5-trimethoxybenzoic acid amides formed particularly with heterocyclic bases have been prepared and examined for toxicity, tranquillizing action and analgesic activity. 3:4:5-Trimethoxybenzoyl morpholine and its 2-methyl derivative displa
Autor:
J. Kuszmann, P. Sohár
Publikováno v:
Carbohydrate Research. 21:19-27
The synthesis of 1,4:3,6-bis(thioanhydro)- D -iditol ( 7 ) and its 2,5-diacetate ( 9 ), starting from 3,4-di- O -methylsulfonyl- D -mannitol is described. Oxidation of 7 led to the corresponding disulfone 10 ; no sulfoxide could be separated. The dia