Zobrazeno 1 - 10
of 6 355
pro vyhledávání: '"J. KATO"'
Publikováno v:
EJC Skin Cancer, Vol 2, Iss , Pp 100122- (2024)
Externí odkaz:
https://doaj.org/article/f558d8699cbb4bd2b98c2b0d2d8102fb
Autor:
Xue Yu, Suvankar Majumdar, J. Daryl Pollard, Erin Jackson, Jarrod Knudson, Douglas Wolfe, Gregory J. Kato, Joseph F. Maher
Publikováno v:
American Journal of Medicine Open, Vol 10, Iss , Pp 100045- (2023)
Background: Sickle cell disease, a common genetic disorder in African Americans, manifests an increased risk of sudden death, the basis of which is incompletely understood. Prolongation of heart rate–corrected QT (QTc) interval on the electrocardio
Externí odkaz:
https://doaj.org/article/1be1d6dcb2704bc5a3b2b9ce78dda33d
Autor:
Tomasz W. Kaminski, Omika Katoch, Ziming Li, Corrine B. Hanway, Rikesh K. Dubey, Adekunle Alagbe, Tomasz Brzoska, Hong Zhang, Prithu Sundd, Gregory J. Kato, Enrico M. Novelli, Tirthadipa Pradhan-Sundd
Publikováno v:
Haematologica, Vol 109, Iss 5 (2023)
Sickle cell disease (SCD) is a monogenic disorder that affects 100,000 African-Americans and millions of people worldwide. Intra-erythrocytic polymerization of sickle hemoglobin (HbS) promotes erythrocyte sickling, impaired rheology, ischemia and hem
Externí odkaz:
https://doaj.org/article/5d47f36e3bc94fdd9f804d4cfcf354eb
Publikováno v:
Natural Products and Bioprospecting, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The Genisteae tribe belongs to the Fabaceae family. The wide occurrence of secondary metabolites, explicitly highlighting the quinolizidine alkaloids (QAs), characterizes this tribe. In the present study, twenty QAs (1–20), including lupan
Externí odkaz:
https://doaj.org/article/cfc8a99a8fbc4e07893106101ecf924a
Autor:
Ana Luisa A. N. Barros, Vladimir C. Silva, Atvaldo F. Ribeiro-Junior, Miguel G. Cardoso, Samuel R. Costa, Carolina B. Moraes, Cecília G. Barbosa, Alex P. Coleone, Rafael P. Simões, Wanessa F. Cabral, Raul M. Falcão, Andreanne G. Vasconcelos, Jefferson A. Rocha, Daniel D. R. Arcanjo, Augusto Batagin-Neto, Tatiana Karla S. Borges, João Gonçalves, Guilherme D. Brand, Lucio H. G. Freitas-Junior, Peter Eaton, Mariela Marani, Massuo J. Kato, Alexandra Plácido, José Roberto S. A. Leite
Publikováno v:
Pharmaceutics, Vol 16, Iss 2, p 190 (2024)
The potential emergence of zoonotic diseases has raised significant concerns, particularly in light of the recent pandemic, emphasizing the urgent need for scientific preparedness. The bioprospection and characterization of new molecules are strategi
Externí odkaz:
https://doaj.org/article/88bb49986b8a49bbb99eea8a6216e672
Autor:
F. Cotinguiba, H. M. Debonsi, R. V. Silva, R. M. Pioli, R. A. Pinto, L. G. Felippe, S. N. López, M. J. Kato, M. Furlan
Publikováno v:
Brazilian Journal of Biology, Vol 82 (2023)
Abstract Several Piper species accumulate piperamides as secondary metabolites, and although they have relevant biological importance, many details of their biosynthetic pathways have not yet been described experimentally. Experiments involving enzym
Externí odkaz:
https://doaj.org/article/4d5a84908220498eb5f482d5ef84f6e2
Autor:
Kathryn A. Uckele, Joshua P. Jahner, Eric J. Tepe, Lora A. Richards, Lee A. Dyer, Kaitlin M. Ochsenrider, Casey S. Philbin, Massuo J. Kato, Lydia F. Yamaguchi, Matthew L. Forister, Angela M. Smilanich, Craig D. Dodson, Christopher S. Jeffrey, Thomas L. Parchman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Foundational hypotheses addressing plant–insect codiversification and plant defense theory typically assume a macroevolutionary pattern whereby closely related plants have similar chemical profiles. However, numerous studies have documente
Externí odkaz:
https://doaj.org/article/a034e4ce05c04cbe807bccc27665887f
Autor:
Rodrigo A. C. Sussmann, Heloisa B. Gabriel, Alejandro García Ríos, Danielle S. Menchaca Vega, Lydia F. Yamaguchi, Antonio Doménech-Carbó, Gerardo Cebrián-Torrejón, Emilia A. Kimura, Massuo J. Kato, Ignasi Bofill Verdaguer, Marcell Crispim, Alejandro M. Katzin
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Malaria is one of the most widespread parasitic diseases, especially in Africa, Southeast Asia and South America. One of the greatest problems for control of the disease is the emergence of drug resistance, which leads to a need for the development o
Externí odkaz:
https://doaj.org/article/a2a0c61706c245b08503bdbba258f959
Autor:
Ana L. A. N. Barros, Abdelaaty Hamed, Mariela Marani, Daniel C. Moreira, Peter Eaton, Alexandra Plácido, Massuo J. Kato, José Roberto S. A. Leite
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Urodele amphibians (∼768 spp.), salamanders and newts, are a rich source of molecules with bioactive properties, especially those isolated from their skin secretions. These include pharmacological attributes, such as antimicrobial, antioxidant, vas
Externí odkaz:
https://doaj.org/article/a40cafaa0adc4eeeb2508575907d9956
Autor:
Ann T. Farrell, Julie Panepinto, Ankit A. Desai, Adetola A. Kassim, Jeffrey Lebensburger, Mark C. Walters, Daniel E. Bauer, Rae M. Blaylark, Donna M. DiMichele, Mark T. Gladwin, Nancy S. Green, Kathryn Hassell, Gregory J. Kato, Elizabeth S. Klings, Donald B. Kohn, Lakshmanan Krishnamurti, Jane Little, Julie Makani, Punam Malik, Patrick T. McGann, Caterina Minniti, Claudia R. Morris, Isaac Odame, Patricia Ann Oneal, Rosanna Setse, Poornima Sharma, Shalini Shenoy
Publikováno v:
Blood Advances, Vol 3, Iss 23, Pp 4002-4020 (2019)
Abstract: To address the global burden of sickle cell disease and the need for novel therapies, the American Society of Hematology partnered with the US Food and Drug Administration to engage the work of 7 panels of clinicians, investigators, and pat
Externí odkaz:
https://doaj.org/article/06caa969e3bd4e5b84bcc4cdd2e86f79