Zobrazeno 1 - 8 of 8 pro vyhledávání: '"J. K. Zjawiony"'
1
Salvinorin A analogues PR-37 and PR-38 attenuate compound 48/80-induced itch responses in mice
Autor: M, Salaga, P R, Polepally, M, Zielinska, M, Marynowski, A, Fabisiak, N, Murawska, K, Sobczak, M, Sacharczuk, J C, Do Rego, B L, Roth, J K, Zjawiony, J, Fichna
Publikováno v: British journal of pharmacology. 172(17)
The opioid system plays a crucial role in several physiological processes in the CNS and in the periphery. It has also been shown that selective opioid receptor agonists exert potent inhibitory action on pruritus and pain. In this study we examined w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3ea9fa5ad00866dddb2834b4740e1b76
https://pubmed.ncbi.nlm.nih.gov/26040667
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3
Marine Natural Products as Lead Anti-HIV Agents
Autor: D J, Gochfeld, K A, El Sayed, M, Yousaf, J F, Hu, P, Bartyzel, D C, Dunbar, S P, Wilkins, J K, Zjawiony, R F, Schinazi, S, Schlueter Wirtz, P M, Tharnish, M T, Hamann
Publikováno v: Mini-Reviews in Medicinal Chemistry. 3:401-424
Current anti-HIV drugs have extreme side effects and resistance to these drugs develops rapidly. The marine environment holds an unprecedented number of unusual chemical structural classes with activity against HIV. We review the literature on anti-H
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25186d89b8754b350ab5615bffd23cb9
https://doi.org/10.2174/1389557033487962
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5
Differential effects of salvinorin A on endotoxin-induced hypermotility and neurogenic ion transport in mouse ileum
Autor: J, Fichna, M, Dicay, S A, Hirota, D, Traboulsi, J A, Macdonald, A, Janecka, P L, Beck, J K, Zjawiony, W K, Macnaughton, M A, Storr
Publikováno v: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 23(6)
Salvinorin A (SA) is the principal active ingredient of Salvia divinorum, with an established inhibitory action on gastrointestinal (GI) transit and colonic ion transport in mice. Under normal conditions, the effects of SA are mediated by kappa opioi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bae7c766a625ba48a114789094fd4a47
https://pubmed.ncbi.nlm.nih.gov/21414104
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6
Salvinorin A inhibits colonic transit and neurogenic ion transport in mice by activating kappa-opioid and cannabinoid receptors
Autor: J, Fichna, R, Schicho, C N, Andrews, M, Bashashati, M, Klompus, D M, McKay, K A, Sharkey, J K, Zjawiony, A, Janecka, M A, Storr
Publikováno v: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 21(12)
The major active ingredient of the plant Salvia divinorum, salvinorin A (SA) has been used to treat gastrointestinal (GI) symptoms. As the action of SA on the regulation of colonic function is unknown, our aim was to examine the effects of SA on mous
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5d22cf19068778cc81d816ac7988ca04
https://pubmed.ncbi.nlm.nih.gov/19650775
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7
Inhibitory effect of salvinorin A, from Salvia divinorum, on ileitis-induced hypermotility: cross-talk between kappa-opioid and cannabinoid CB(1) receptors
Autor: CAPASSO, RAFFAELE, BORRELLI, FRANCESCA, M. G. Cascio, G. Aviello, K. Huben, J. K. Zjawiony, P. Marini, ROMANO, BARBARA, V. Di Marzo, CAPASSO, FRANCESCO, IZZO, ANGELO ANTONIO
BACKGROUND AND PURPOSE: Salvinorin A, the active component of the hallucinogenic herb Salvia divinorum, inhibits intestinal motility through activation of kappa-opioid receptors (KORs). However, this compound may have target(s) other than the KORs in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3730::e4263338447bedcf5da798f1c55ae2fa
http://hdl.handle.net/11588/333247
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8
Ultrapotent effects of salvinorin A, a hallucinogenic compound from Salvia divinorum, on LPS-stimulated murine macrophages and its anti-inflammatory action in vivo
Autor: Kevin Lewellyn, Raffaele Capasso, Livio Luongo, Sabatino Maione, Francesca Borrelli, Gabriella Aviello, Angelo A. Izzo, Maria De Chiaro, Barbara Romano, Jordan K. Zjawiony, Francesca Guida
Publikováno v: Journal of Molecular Medicine. 89:891-902
The hallucinogenic compound, salvinorin A, is a potent κ-opioid receptor (KOR) agonist. However, other target(s) than the KOR, such as the cannabinoid CB1 receptor, have been proposed to explain its multiple pharmacological actions. Here, we have ev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a17151afb3ac49fa9b8c23cbad58ba9f
https://doi.org/10.1007/s00109-011-0752-4
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