Zobrazeno 1 - 10
of 242
pro vyhledávání: '"J. K. Williams"'
Autor:
Amy C. Thomas, Elizabeth Oliver, Holly E. Baum, Kapil Gupta, Kathryn L. Shelley, Anna E. Long, Hayley E. Jones, Joyce Smith, Benjamin Hitchings, Natalie di Bartolo, Kate Vasileiou, Fruzsina Rabi, Hanin Alamir, Malak Eghleilib, Ore Francis, Jennifer Oliver, Begonia Morales-Aza, Ulrike Obst, Debbie Shattock, Rachael Barr, Lucy Collingwood, Kaltun Duale, Niall Grace, Guillaume Gonnage Livera, Lindsay Bishop, Harriet Downing, Fernanda Rodrigues, Nicholas Timpson, Caroline L. Relton, Ashley Toye, Derek N. Woolfson, Imre Berger, Anu Goenka, Andrew D. Davidson, Kathleen M. Gillespie, Alistair J. K. Williams, Mick Bailey, Ellen Brooks-Pollock, Adam Finn, Alice Halliday, the CoMMinS Study Team
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-14 (2023)
Thomas et al. test 6 ELISAs detecting IgA and IgG antibodies to whole SARS-CoV-2 spike protein, to its receptor binding domain region and to nucleocapsid protein in saliva. Across 20 household outbreaks, antibody responses are heterogeneous, but a re
Externí odkaz:
https://doaj.org/article/55c6b79ee60943e99ecc0c4b2dc196bb
Autor:
Sian L. Grace, Georgina L. Mortimer, Aizhan Kozhakhmetova, Jamie Leveret, Richard Newton, Koit Reimand, Julian P. H. Shield, Raivo Uibo, Alistair J. K. Williams, Kathleen M. Gillespie
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionAutoimmune diabetes occurs more often in the first 2 years of life in children with Down syndrome (DS) compared with the general population. We previously observed increased frequencies of islet autoantibodies, including insulin autoantib
Externí odkaz:
https://doaj.org/article/27fa845a57e64135b4f7960fd17a14e9
Autor:
Alice Halliday, Anna E. Long, Holly E. Baum, Amy C. Thomas, Kathryn L. Shelley, Elizabeth Oliver, Kapil Gupta, Ore Francis, Maia Kavanagh Williamson, Natalie Di Bartolo, Matthew J. Randell, Yassin Ben-Khoud, Ilana Kelland, Georgina Mortimer, Olivia Ball, Charlie Plumptre, Kyla Chandler, Ulrike Obst, Massimiliano Secchi, Lorenzo Piemonti, Vito Lampasona, Joyce Smith, Michaela Gregorova, Lea Knezevic, Jane Metz, Rachael Barr, Begonia Morales-Aza, Jennifer Oliver, Lucy Collingwood, Benjamin Hitchings, Susan Ring, Linda Wooldridge, Laura Rivino, Nicholas Timpson, Jorgen McKernon, Peter Muir, Fergus Hamilton, David Arnold, Derek N. Woolfson, Anu Goenka, Andrew D. Davidson, Ashley M. Toye, Imre Berger, Mick Bailey, Kathleen M. Gillespie, Alistair J. K. Williams, Adam Finn
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Low-volume antibody assays can be used to track SARS-CoV-2 infection rates in settings where active testing for virus is limited and remote sampling is optimal. We developed 12 ELISAs detecting total or antibody isotypes to SARS-CoV-2 nucleocapsid, s
Externí odkaz:
https://doaj.org/article/305a69f5b981428bab7c739f99a8b141
Publikováno v:
Structural Concrete. 24:2071-2092
Autor:
C L, Williams, R, Fareed, G L M, Mortimer, R J, Aitken, I V, Wilson, G, George, K M, Gillespie, A J K, Williams, Chandan, Yaliwal
Publikováno v:
Williams, C L, Fareed, R Y Y, Mortimer, G L M, Aitken, R J, Wilson, I V, George, G M, Gillespie, K M & Long, A E 2022, ' The longitudinal loss of islet autoantibody responses from diagnosis of type 1 diabetes occurs progressively over follow-up and is determined by low autoantibody titres, early-onset, and genetic variants. ', Clinical and Experimental Immunology, vol. 210, no. 2, pp. 151-162 . https://doi.org/10.1093/cei/uxac087
The clinical usefulness of post-diagnosis islet autoantibody levels is unclear and factors that drive autoantibody persistence are poorly defined in type 1 diabetes (T1D). Our aim was to characterise the longitudinal loss of islet autoantibody respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff77272eb703bdf3a7aca29c04a5aca
https://research-information.bris.ac.uk/en/publications/eb032000-0504-4526-9f37-20313bd0a346
https://research-information.bris.ac.uk/en/publications/eb032000-0504-4526-9f37-20313bd0a346
Autor:
David I. W. Phillips, Alice Holmes, Hannah F. Wilson, Tanwi Vartak, Diana L. Cousminer, Arla Gamper, Kenyaita M. Hodge, Kim Lorenz, Samuel T. Jerram, Stanley Schwartz, Elisabeth R. Trimble, Alistair J K Williams, Shitaye Alemu Balcha, Abayneh Girma Demisse, R. David Leslie, Struan F.A. Grant, Rajashree Mishra, Benjamin F. Voight
Publikováno v:
Diabetologia
Balcha, S A, Demisse, A G, Mishra, R, Vartak, T, Cousminer, D L, Hodge, K M, Voight, B F, Lorenz, K, Schwartz, S, Jerram, S T, Gamper, A, Holmes, A, Wilson, H F, Williams, A J K, Grant, S F A, Leslie, R D, Phillips, D I W & Trimble, E R 2020, ' Type 1 diabetes in Africa : an immunogenetic study in the Amhara of North-West Ethiopia ', Diabetologia . https://doi.org/10.1007/s00125-020-05229-x
Balcha, S A, Demisse, A G, Mishra, R, Vartak, T, Cousminer, D L, Hodge, K M, Voight, B F, Lorenz, K, Schwartz, S, Jerram, S T, Gamper, A, Holmes, A, Wilson, H F, Williams, A J K, Grant, S F A, Leslie, R D, Phillips, D I W & Trimble, E R 2020, ' Type 1 diabetes in Africa an immunogenetic study in the Amhara of North-West Ethiopia ', Diabetologia, vol. 63, no. 10, pp. 2158-2168 . https://doi.org/10.1007/s00125-020-05229-x
Balcha, S A, Demisse, A G, Mishra, R, Vartak, T, Cousminer, D L, Hodge, K M, Voight, B F, Lorenz, K, Schwartz, S, Jerram, S T, Gamper, A, Holmes, A, Wilson, H F, Williams, A J K, Grant, S F A, Leslie, R D, Phillips, D I W & Trimble, E R 2020, ' Type 1 diabetes in Africa : an immunogenetic study in the Amhara of North-West Ethiopia ', Diabetologia . https://doi.org/10.1007/s00125-020-05229-x
Balcha, S A, Demisse, A G, Mishra, R, Vartak, T, Cousminer, D L, Hodge, K M, Voight, B F, Lorenz, K, Schwartz, S, Jerram, S T, Gamper, A, Holmes, A, Wilson, H F, Williams, A J K, Grant, S F A, Leslie, R D, Phillips, D I W & Trimble, E R 2020, ' Type 1 diabetes in Africa an immunogenetic study in the Amhara of North-West Ethiopia ', Diabetologia, vol. 63, no. 10, pp. 2158-2168 . https://doi.org/10.1007/s00125-020-05229-x
Aims/hypothesis We aimed to characterise the immunogenic background of insulin-dependent diabetes in a resource-poor rural African community. The study was initiated because reports of low autoantibody prevalence and phenotypic differences from Europ
Autor:
Kapil Gupta, Andrew D. Davidson, Michaela Gregorova, Adam Finn, Amy Thomas, Anu Goenka, Vito Lampasona, Holly Baum, Maia Kavanagh Williamson, Alice Halliday, Kathleen M Gillespie, Elizabeth Oliver, Barry Vipond, Emily Milodowski, Laura Rivino, Lorenzo Piemonti, Imre Berger, Mick Bailey, Ashley M. Toye, Alistair J K Williams, Peter Muir, Anna E. Long, Natalie D. Di Bartolo, Linda Wooldridge, Lea Knezevic, Jolanta Bernatoniene
Publikováno v:
Cell Reports Medicine
Goenka, A, Halliday, A, Gregorova, M, Milodowski, E J, Thomas, A, Kavanagh Williamson, M, Baum, H E, Oliver, E H, Long, A E, Knezevic, L, Gupta, K, Di Bartolo, N D, Berger, I, Toye, A M, Bernatoniene, J, Bailey, M, Gillespie, K M, Davidson, A D, Wooldridge, L, Rivino, L & Finn, A 2021, ' Young infants exhibit robust functional antibody responses and restrained IFN-γ production to SARS-CoV-2 ', Cell Reports Medicine, vol. 2, no. 7, 100327 . https://doi.org/10.1016/j.xcrm.2021.100327
Goenka, A, Halliday, A, Gregorova, M, Milodowski, E J, Thomas, A, Kavanagh Williamson, M, Baum, H E, Oliver, E H, Long, A E, Knezevic, L, Gupta, K, Di Bartolo, N D, Berger, I, Toye, A M, Bernatoniene, J, Bailey, M, Gillespie, K M, Davidson, A D, Wooldridge, L, Rivino, L & Finn, A 2021, ' Young infants exhibit robust functional antibody responses and restrained IFN-γ production to SARS-CoV-2 ', Cell Reports Medicine, vol. 2, no. 7, 100327 . https://doi.org/10.1016/j.xcrm.2021.100327
Severe COVID-19 appears rare in children. This is unexpected, especially in young infants, who are vulnerable to severe disease caused by other respiratory viruses. We evaluate convalescent immune responses in 4 infants under 3 months old with confir
Autor:
Claire H Caygill, Anna E. Long, Kathleen M Gillespie, Dalė Marčiulionytė, Alistair J K Williams
Publikováno v:
Long, A E, Caygill, C, Gillespie, K M, Marčiulionytė, D & Williams, A J K 2020, ' Islet autoantibody profiles associated with higher diabetes risk in Lithuanian compared with English schoolchildren ', Clinical and Experimental Immunology . https://doi.org/10.1111/cei.13524
Clinical and Experimental Immunology
Clinical and experimental immunology, Hoboken : Wiley, 2021, vol. 203, no. 1, p. 41-46
Clinical and Experimental Immunology
Clinical and experimental immunology, Hoboken : Wiley, 2021, vol. 203, no. 1, p. 41-46
This study used recently developed, more specific islet autoantibody tests, to characterise differences in humoral autoimmunity between two childhood general population cohorts, from Lithuania and England, in greater detail. The new data support our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3809af7b5a279b099334f73ee35082c
https://research-information.bris.ac.uk/en/publications/a8271417-5d4c-4695-968f-970a24e45578
https://research-information.bris.ac.uk/en/publications/a8271417-5d4c-4695-968f-970a24e45578
Autor:
Janice D. Wagner, J K Williams, Claude L. Hughes, Thomas B. Clarkson, JM Cline, Mary S. Anthony
Publikováno v:
Progress in the Management of the Menopause ISBN: 9781003076575
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c503a0832aa05367f32bb86ace20fda
https://doi.org/10.1201/9781003076575-6
https://doi.org/10.1201/9781003076575-6
Publikováno v:
Progress in the Management of the Menopause ISBN: 9781003076575
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2b769d15b2ac821db38ffcdca5f5667
https://doi.org/10.4324/9781003076575-6
https://doi.org/10.4324/9781003076575-6