Zobrazeno 1 - 2
of 2
pro vyhledávání: '"J. K. Wakefield"'
Autor:
Warren J. Strittmatter, James R. Burke, S. Y. Bae, Carol A. Colton, Ayyappan Nair, Q. Xu, J. K. Wakefield, Michael P. Vitek
Publikováno v:
The Journal of Neuroscience. 24:7118-7127
Our data suggest a novel mechanism whereby pathological-length polyglutamine (polyQ) proteins promote the spermine synthetic pathway, increasing polyQ-aggregation and cell death. As detected in a cell-free turbidity assay, spermine promotes aggregati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794f2cbc19ad9845ff6c9428d5696750
https://doi.org/10.1523/jneurosci.1233-04.2004
https://doi.org/10.1523/jneurosci.1233-04.2004
Publikováno v:
Developments in biologicals. 106
Lentiviral vectors hold great promise for gene therapy, and clinical trials to examine their safety and efficacy for treating human disease are being planned. The principle concern for safety is that genetic recombination among components of the vect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::afa313a2020da0cfc3a70abc69c4fbe3
https://pubmed.ncbi.nlm.nih.gov/11761237
https://pubmed.ncbi.nlm.nih.gov/11761237