Výsledky vyhledávání - "J. K. Vishwanatha"

Fragile histidine triad gene expression in primary prostate cancer and in an in vitro model

Autor: Z, Guo, S L, Johansson, J S, Rhim, J K, Vishwanatha

Publikováno v: The Prostate. 43(2)

The fragile histidine triad (FHIT) is frequently deleted and altered in many human cancers. Replacement of the FHIT gene into cancer cell lines lacking FHIT expression results in loss of tumorigenicity and tumor growth.We investigated the status and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3e5b11e8b820557f47db7594e8bddb0f
https://pubmed.ncbi.nlm.nih.gov/10754525

Zobrazit plný text záznamu

Effect of regulated expression of the fragile histidine triad gene on cell cycle and proliferation

Autor: Z, Guo, J K, Vishwanatha

Publikováno v: Molecular and cellular biochemistry. 204(1-2)

The mechanism of tumor suppressor action of the fragile histidine triad (FHIT) gene is unknown. Disruption of cell cycle regulation leads to the tumor formation and many tumor suppressor genes suppress tumorigenesis through their effect on cell cycle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b3291db564090953fa20e868d5ef5cc1
https://pubmed.ncbi.nlm.nih.gov/10718628

Zobrazit plný text záznamu

Role of nitric oxide in the induction of apoptosis by smokeless tobacco extract

Autor: R S, Mangipudy, J K, Vishwanatha

Publikováno v: Molecular and cellular biochemistry. 200(1-2)

Smokeless tobacco usage is a growing public health concern in the United States. Lesions of the oral cavity have been clearly linked to smokeless tobacco use. The objective of this study was to determine the biochemical effects of smokeless tobacco e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5aea03cff6056fbe758d9f9076a89c61
https://pubmed.ncbi.nlm.nih.gov/10569183

Zobrazit plný text záznamu

Specific down-regulation of annexin II expression in human cells interferes with cell proliferation

Autor: Y, Chiang, A, Rizzino, Z A, Sibenaller, M S, Wold, J K, Vishwanatha

Publikováno v: Molecular and cellular biochemistry. 199(1-2)

The protein-tyrosine kinase substrate annexin II is a growth regulated gene whose expression is increased in several human cancers. While the precise function of this protein is not understood, annexin II is proposed to be involved in multiple physio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a3b23d269e5acb10c9e17fbdc5486fc3
https://pubmed.ncbi.nlm.nih.gov/10544962

Zobrazit plný text záznamu

Annexin I degradation in bronchoalveolar lavage fluids from healthy smokers: a possible mechanism of inflammation

Autor: J K, Vishwanatha, R G, Davis, I, Rubinstein, A, Floreani

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 4(10)

Annexin I is a glucocorticoid-inducible, phospholipase A2-inhibitory protein and is proposed to have an anti-inflammatory role. Although annexin I is a cytosolic protein, it is found extracellularly in secreted fluids such as semen. We have examined

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::95344715331a82931833a1c13eb9f169
https://pubmed.ncbi.nlm.nih.gov/9796991

Zobrazit plný text záznamu

Mechanisms of smokeless tobacco-induced oral mucosa inflammation: role of bradykinin

Autor: X P, Gao, J K, Vishwanatha, J M, Conlon, C O, Olopade, I, Rubinstein

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 157(10)

The purpose of this study was to determine whether an aqueous extract of smokeless tobacco (moist snuff) increases clearance of macromolecules from postcapillary venules in the in situ oral mucosa and, if so, whether bradykinin mediated this response

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dd899b3f451a53c2a0e4662d8fc2f07d
https://pubmed.ncbi.nlm.nih.gov/8906842

Zobrazit plný text záznamu

Annexin II expression is regulated during mammalian cell cycle

Autor: Y, Chiang, M H, Schneiderman, J K, Vishwanatha

Publikováno v: Cancer research. 53(24)

Annexin II is a substrate for oncogene and growth factor-associated protein-tyrosine kinases. Elevated expression of annexin II is seen in different types of cancers and recent evidence indicates a role for annexin II in DNA synthesis and cell prolif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::70cd57da56bdd62aef56a31ff6d537f9
https://pubmed.ncbi.nlm.nih.gov/8261416

Zobrazit plný text záznamu

Enhanced levels of annexins in pancreatic carcinoma cells of Syrian hamsters and their intrapancreatic allografts

Autor: K D, Kumble, M, Hirota, P M, Pour, J K, Vishwanatha

Publikováno v: Cancer research. 52(1)

Annexins are a family of calcium- and phospholipid-binding proteins related by amino acid sequence homology. Annexins I and II are substrates for protein tyrosine kinases. Recent investigations have revealed a possible involvement of annexins I and I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::714b4be085d42b9a5703a19d1d049de7
https://pubmed.ncbi.nlm.nih.gov/1530768

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání