Zobrazeno 1 - 10
of 18
pro vyhledávání: '"J. K. Ritter"'
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 28(9)
The UDP-glucuronosyltransferases (UGTs) have long been known to be inducible by various chemicals, including drugs, although the extent of induction in general has been modest. In the present study, we determined the ability of the dietary flavonoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5c073629ebd7ac3e234cc4b728414ab
https://pubmed.ncbi.nlm.nih.gov/10950852
https://pubmed.ncbi.nlm.nih.gov/10950852
Autor:
I S, Owens, J K, Ritter
Publikováno v:
Progress in nucleic acid research and molecular biology. 51
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a32c914786c810c2a9184a8b19c50e6c
https://pubmed.ncbi.nlm.nih.gov/7659777
https://pubmed.ncbi.nlm.nih.gov/7659777
Publikováno v:
The Journal of clinical investigation. 93(2)
Accumulating evidence indicates that mutations in the human UGT1 gene locus abolish hepatic bilirubin UDP-glucuronosyltransferase activity and cause the subsequent accumulation of bilirubin to toxic levels in patients with Crigler-Najjar type 1 (CN-I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22498c80c78502d611d1353bd79b14e
https://pubmed.ncbi.nlm.nih.gov/7906695
https://pubmed.ncbi.nlm.nih.gov/7906695
Autor:
Patrick J. Coyne, Thomas J. Smith, D. S. Fletcher, G. L. Parker, Patricia Dodson, J. K. Ritter
Publikováno v:
Journal of Clinical Oncology. 29:9021-9021
9021 Background: Nausea and vomiting due to cancer or its treatment is a common symptom in oncology, palliative care and hospice. ABH topical gel is currently widely used in home hospice due to per...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6033685f4b4614fb316b010d8bfe9772
https://doi.org/10.1200/jco.2011.29.15_suppl.9021
https://doi.org/10.1200/jco.2011.29.15_suppl.9021
Publikováno v:
The Journal of biological chemistry. 268(31)
The characterization (Ritter, J. K., Chen, F., Sheen, Y. Y., Tran, H. M., Kimura, S., Yeatman, M. T., and Owens, I. S. (1992) J. Biol. Chem. 267, 3257-3261) of the single-copy UGT1 gene complex encoding both bilirubin and phenol UDP-glucuronosyltrans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::87189824bde1b2d254e7d3879d07c471
https://pubmed.ncbi.nlm.nih.gov/8226884
https://pubmed.ncbi.nlm.nih.gov/8226884
Publikováno v:
The Journal of biological chemistry. 267(5)
Two human liver UDP-glucuronosyltransferase (transferase) cDNAs, HUG-Br1 and HUG-Br2, were previously isolated (Ritter, J. K., Crawford, J. M., and Owens, I. S. (1991) J. Biol. Chem. 266, 1043-1047), and each was shown to encode a bilirubin transfera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::493a0808ad1c88428ee298d0f74f33ad
https://pubmed.ncbi.nlm.nih.gov/1339448
https://pubmed.ncbi.nlm.nih.gov/1339448
Publikováno v:
The Journal of biological chemistry. 266(2)
We report the isolation and characterization of two human liver cDNA clones, HUG-Br1 and HUG-Br2; each encodes a UDP-glucuronosyltransferase enzyme which glucuronidates bilirubin IX alpha to form both the IX alpha C8 and IX alpha C12 monoconjugates a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ae59aebcaeb6045f65031f6e84b158c
https://pubmed.ncbi.nlm.nih.gov/1898728
https://pubmed.ncbi.nlm.nih.gov/1898728
Publikováno v:
The Journal of biological chemistry. 265(14)
The human cDNA clone, UDPGTh-2, encoding a liver UDP-glucuronosyltransferase (transferase) was isolated from a lambda gt11 cDNA library by hybridization to the mouse transferase cDNA clone, UDPGTm-1 (Kimura, T., and Owens, I. S. (1987) Eur. J. Bioche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b7576e1b27582a2ab1b64d44987c685
https://pubmed.ncbi.nlm.nih.gov/2159463
https://pubmed.ncbi.nlm.nih.gov/2159463
Publikováno v:
Biochemical Pharmacology. 34:3161-3166
The results reported herein strongly suggest that increased dopaminergic and not increased serotonergic activity is responsible for methamphetamine-induced increases in the nigral concentration of substance P-like immunoreactivity (SPLI). Thus, treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1beffde020a4be4721d59114947dbbf
https://doi.org/10.1016/0006-2952(85)90163-7
https://doi.org/10.1016/0006-2952(85)90163-7
Publikováno v:
European Journal of Pharmacology. 128:265-268
Administration of methamphetamine (METH) has been shown to increase substance P (SP) concentrations in striatonigral structures. Data described herein demonstrate that SP pathways associated with the mesolimbic systems also are influenced by METH tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce0d97b7f1ed5106b2dfa98ed72d70da
https://doi.org/10.1016/0014-2999(86)90775-2
https://doi.org/10.1016/0014-2999(86)90775-2