Zobrazeno 1 - 10
of 20
pro vyhledávání: '"J. K. O'Donnell"'
Autor:
J Okabe, C Adams, K Sundarapandiyan, S P White, A S Acharya, C T Parsons, Michael J. Martin, B N Manjula, Patrick Birch, J K O'Donnell
Publikováno v:
Journal of Biological Chemistry. 269:27692-27699
Hemoglobin A (HbA) and two low oxygen affinity variants of HbA, HbPresbyterian and HbYoshizuka, were produced in transgenic pigs and purified to homogeneity by ion-exchange chromatography. These two variants contain either lysine (HbPresbyterian) or
Autor:
J K O'Donnell, Enrico Bucci, Zygmunt Gryczynski, William S. Brinigar, Janusz Kowalczyk, Clara Fronticelli, John S. Olson
Publikováno v:
Biochemistry. 32:1235-1242
Using the mutagenesis and a gene expression system previously described [Fronticelli et al. (1991) J. Protein Chem. 10, 495-501], we have replaced Val67E11 in the distal heme pocket of the beta-chains of hemoglobin with Thr. The valine to threonine s
Autor:
W Lago, M E Swanson, Michael J. Martin, V Huntress, Stephen H. Pilder, J K O'Donnell, John S. Logan, Carl A. Pinkert, C T Parsons, K Hoover
Publikováno v:
Scopus-Elsevier
A construct containing the locus control region (LCR) from the human beta globin locus together with two copies of the human alpha 1 gene and a single copy of the human beta A gene was used to obtain three transgenic pigs. The transgenic pigs are hea
Autor:
S C, Morrison, J K, O'Donnell
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 38(11)
Renal cortical imaging with 99mTc-dimercaptosuccinic acid (DMSA) has become the imaging test of choice for the diagnosis of acute pyelonephritis. An unusual uptake pattern was observed in a child receiving chemotherapy for a bladder rhabdomyosarcoma.
Publikováno v:
The American surgeon. 63(7)
Bile leaks are a recognized complication of laparoscopic cholecystectomy (LC). Different diagnostic approaches have been employed when this condition is suspected. We present our experience with cholescintigraphy as a primary imaging technique for th
Publikováno v:
Journal of nuclear medicine technology. 25(2)
PET tumor imaging of the abdomen and pelvis is prone to artifacts due to urinary tract activity. A new technique has been developed to reduce such artifacts and enhance study interpretation.Thirty minutes after the injection of 18F-FDG, 500 cc 0.45%
Autor:
J K, O'Donnell, M K, Gaedeke
Publikováno v:
Critical care nursing clinics of North America. 7(3)
Sudden infant death syndrome (SIDS) is a perplexing and troubling problem for health care professionals and the community. This article discusses the epidemiology of SIDS and nursing interventions to meet the needs of families affected by SIDS.
Publikováno v:
Cancer detection and prevention. 17(2)
Many significant challenges have to be met before a clinically useful hemoglobin-based blood substitute can be developed. A major issue is the choice of a production system. Transgenic swine have several features that appear to be suited to the abund
Publikováno v:
Journal of neurochemistry. 58(3)
The role of the alpha subunit of the guanine nucleotide-binding regulatory protein that stimulates adenylyl cyclase (GS alpha) in the down-regulation of beta-adrenergic receptors by pindolol was studied in S49 cyc- cells (normally GS alpha-deficient)
Publikováno v:
Journal of protein chemistry. 10(5)
A plasmid analogous to the one described by Nagai and Thogersen (Nature, 309, 810-812, 1984) has been constructed for the expression of globins in E. coli. Induction with nalidixic acid produces high yields of a fusion protein, NS1-FX-beta-globin, wh