Zobrazeno 1 - 10
of 23
pro vyhledávání: '"J. K. Blusztajn"'
Publikováno v:
Digestive Diseases and Sciences. 40:1982-1989
Acetylcholine may be released from gallbladder intrinsic nerves in response to cholecystokinin stimulation. This study characterized metabolites of [14C]choline produced in the gallbladder and released during incubation, with or without cholecystokin
Publikováno v:
Journal of Biological Chemistry. 268:2100-2105
Choline deficiency, via deprivation of labile methyl groups, is associated with a greatly increased incidence of hepatocarcinoma in experimental animals. This dietary deficiency also causes fatty liver, because choline is needed for hepatic secretion
Autor:
I, López-Coviella, J K, Blusztajn
Publikováno v:
Revista de neurologia. 33(11)
The discovery and characterization of factors that induce and maintain specific neurotransmitter phenotypes has profound clinical implications, and continues to be one of the major objectives in the neurosciences.Although much progress has been reali
Autor:
Juan Ramón Martínez-Morales, Rafael Alonso, JG Hernandez-Jimenez, J. K. Blusztajn, I. López-Coviella, Ricardo Reyes, Guadalberto Hernández, A. R. Bello
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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7 páginas, 3 figuras, 1 tabla.
The function of a particular neuronal population is in part determined by its neurotransmitter phenotype. We have found that a neuronal-derived septal cell line (SN56), known for its cholinergic properties, also s
The function of a particular neuronal population is in part determined by its neurotransmitter phenotype. We have found that a neuronal-derived septal cell line (SN56), known for its cholinergic properties, also s
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 14(14)
Brain cells in Alzheimer's disease (AD) exhibit a membrane defect characterized by accelerated phospholipid turnover. The mechanism responsible for this defect remains unknown. Recent studies indicate that impairment of mitochondrial function is freq
Publikováno v:
Journal of neuroscience research. 57(1)
The rate of acetylcholine (ACh) synthesis was found to depend on the activity of choline acetyltransferase (ChAT) and on the concentrations of the two substrates of this enzyme, choline and acetyl-CoA. In SN56 cells treated for 3 days with 1 mM dbcAM
Autor:
P I, Johnson, J K, Blusztajn
Publikováno v:
Neurochemical research. 23(5)
Phosphatidylethanolamine N-methyltransferase (PEMT) activity was measured by a radioenzymatic assay in homogenates of brain and liver obtained from Sprague Dawley rats fed a choline-free or control (0.3 g/kg of choline chloride) diet for seven days.
Publikováno v:
Neurotoxicology. 18(1)
In toxicology, the need to reduce uncertainties in human risk assessment is met by understanding why species and individuals within that species respond differently to chemical exposure. This kind of information is needed when extrapolating data from
Publikováno v:
Folia neuropathologica. 35(4)
Cholinergic hybrid mouse septal neurons SN56 were differentiated by separate and combined application of 0.001 mM all-trans-retinoic acid and 1 mM dibutyryl cAMP. Each of agents caused about twofold increase of choline acetyltransferase activity. The
Autor:
P L, Hudson, W A, Pedersen, W S, Saltsman, M, Liscovitch, D T, MacLaughlin, P K, Donahoe, J K, Blusztajn
Publikováno v:
The Journal of biological chemistry. 269(34)
Receptor-activated breakdown of complex sphingolipids has been proposed as a mechanism for generating sphingoid base-containing putative second messenger molecules whose actions may modulate responses to extracellular signals. In human epidermoid car