Structural analysis of receptors and actin polarity in platelet protrusions

Autor: Bruno Martins, J. Jiménez de la Morena, Ohad Medalia, E. Fernández-Giménez, Roberto Melero, Matthias Eibauer, Ana Maria Cuervo, Carlos Oscar S. Sorzano, Federico P. de Isidro-Gómez, José Javier Conesa, Jan-Dirk Studt, José María Carazo, Simona Sorrentino

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
PNAS Vol. 118 | No. 37

Significance Platelet activation induces reorganization of the cell and the formation of cellular protrusions, pseudopodia. These processes are accompanied by remodeling of the actin cytoskeleton and the activation of platelet integrins, which mediat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b376e2128ff4dd1591b6d0c5ee19d4b9
http://europepmc.org/articles/PMC8449362

Algorithmic robustness to preferred orientations in single particle analysis by CryoEM

Autor: María Jesús Martínez, Pablo Conesa, Roberto Marabini, Remedios Melero, A. Jiménez-Moreno, Erney Ramírez-Aportela, F. de Isidro, Barry D. Bruce, S. Vacca, C.O.S. Sorzano, Ana Maria Cuervo, David Maluenda, Yunior C. Fonseca, Dmitry A. Semchonok, Y.-C. Lo, L. del Cano, J. Jiménez de la Morena, David Herreros, Patricia Losana, Su Chang Lin, José María Carazo, Panagiotis L. Kastritis, E. Fernández-Giménez, José Luis Vilas, M. Gragera, José Javier Conesa, David Strelak, Rubén J. Sánchez-García

Publikováno v: Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Journal of Structural Biology

The presence of preferred orientations in single particle analysis (SPA) by cryo-Electron Microscopy (cryoEM) is currently one of the hurdles preventing many structural analyses from yielding high-resolution structures. Although the existence of pref

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d319f9f07d13bd519b71eccc9f686b2b
http://hdl.handle.net/10486/701359

Magnetic properties of iron oxide nanoparticles prepared by seeded-growth route

Autor: Alessandra Quarta, Albert Figuerola, Ana Espinosa, M. Garcia-Hernandez, Claire Wilhelm, Aida Serrano, J. Jiménez de la Morena, Miguel A. García, Álvaro Muñoz-Noval, Teresa Pellegrino

Publikováno v: Journal of nanoparticle research 15 (2013). doi:10.1007/s11051-013-1514-8
info:cnr-pdr/source/autori:Espinosa A. [ 1 ] ; Munoz-Noval A. [ 2,3 ] ; Garcia-Hernandez M. [ 1 ] ; Serrano A. [ 2 ] ; de la Morena J. J. [ 1,2 ] ; Figuerola A. [ 4,5 ] ; Quarta A. [ 6 ] ; Pellegrino T. [ 6,7 ] ; Wilhelm C. [ 8,9 ] ; Garcia M. A. [ 2 ]/titolo:Magnetic properties of iron oxide nanoparticles prepared by seeded-growth route/doi:10.1007%2Fs11051-013-1514-8/rivista:Journal of nanoparticle research/anno:2013/pagina_da:/pagina_a:/intervallo_pagine:/volume:15
Journal of Nanoparticle Research
Digital.CSIC. Repositorio Institucional del CSIC
instname

In this work we investigate the magnetic properties of iron oxide nanoparticles obtained by two-step synthesis (seeded-growth route) with sizes that range from 6 to 18 nm. The initial seeds result monocrystalline and exhibit ferromagnetic behavior wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5bf936c997c637dc7374eedc9efa078
https://doi.org/10.1007/s11051-013-1514-8

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On bias, variance, overfitting, gold standard and consensus in single-particle analysis by cryo-electron microscopy

Autor: C. O. S. Sorzano, A. Jiménez-Moreno, D. Maluenda, M. Martínez, E. Ramírez-Aportela, J. Krieger, R. Melero, A. Cuervo, J. Conesa, J. Filipovic, P. Conesa, L. del Caño, Y. C. Fonseca, J. Jiménez-de la Morena, P. Losana, R. Sánchez-García, D. Strelak, E. Fernández-Giménez, F. P. de Isidro-Gómez, D. Herreros, J. L. Vilas, R. Marabini, J. M. Carazo

Publikováno v: Acta Crystallogr D Struct Biol

Cryo-electron microscopy (cryoEM) has become a well established technique to elucidate the 3D structures of biological macromolecules. Projection images from thousands of macromolecules that are assumed to be structurally identical are combined into

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dc9ec642ca8c005c250986432bf94c7