Zobrazeno 1 - 10
of 34
pro vyhledávání: '"J. Jeremiah Bell"'
Autor:
Shannon L. Carpenter, Jennifer L. Goldman, Dale E. Jarka, Jason G. Newland, Rangaraj Selvarangan, J. Jeremiah Bell, Katherine Chastain, Suresh Selveraju, Ashley K. Sherman
Publikováno v:
Thrombosis Research. 138:69-73
Objectives Children with Staphylococcus aureus (SA) bacteremia risk developing venous thromboembolism (VTE). We sought to identify clinical variables and bacterial virulence factors associated with VTE in SA bacteremia. Study design This is a single-
Publikováno v:
Blood. 121:64-71
The mouse thymus supports T-cell development, but also contains non–T-cell lineages such as dendritic cells, macrophages, and granulocytes that are necessary for T-cell repertoire selection and apoptotic thymocyte clearance. Early thymic progenitor
Publikováno v:
Immunological Reviews. 238:12-22
T cells originate from hematopoietic stem cells (HSCs) in the bone marrow but complete their development in the thymus. HSCs give rise to a variety of non-renewing hematopoietic progenitors, among which a rare subset migrates to the thymus via the bl
Autor:
Benjamin A. Schwarz, Arivazhagan Sambandam, Avinash Bhandoola, Daniel A. Zlotoff, Theodore D. Logan, J. Jeremiah Bell
Publikováno v:
Blood. 115:1897-1905
T lymphopoiesis requires settling of the thymus by bone marrow–derived precursors throughout adult life. Progenitor entry into the thymus is selective, but the molecular basis of this selectivity is incompletely understood. The chemokine receptor C
Publikováno v:
Current Opinion in Immunology. 21:121-126
T cells develop in the thymus. Previous work suggested an early separation of lymphoid from myeloerythroid lineages during hematopoiesis, and hypothesized the thymus was settled exclusively by lymphoid-restricted hematopoietic progenitors. Recent dat
Autor:
J. Jeremiah Bell, Avinash Bhandoola
Publikováno v:
Nature. 452:764-767
There exists controversy over the nature of haematopoietic progenitors of T cells. Most T cells develop in the thymus, but the lineage potential of thymus-colonizing progenitors is unknown. One approach to resolving this question is to determine the
Autor:
Christine M. Hoeman, Habib Zaghouani, Ping Yu, Hyun Hee Lee, Jason S. Ellis, Danielle M. Tartar, Rohit D. Divekar, F. Betul Guloglu, Renu Jain, J. Jeremiah Bell
Publikováno v:
The Journal of Immunology. 180:179-187
Currently, transition of T cells from effector to memory is believed to occur as a consequence of exposure to residual suboptimal Ag found in lymphoid tissues at the waning end of the effector phase and microbial clearance. This led to the interpreta
Autor:
Gary S. Sayler, J. Jeremiah Bell, Booki Min, Jacque C. Caprio-Young, Hyun Hee Lee, Habib Zaghouani, Danielle Nast, Jason S. Ellis
Publikováno v:
The Journal of Immunology. 176:357-364
Ig-proteolipid protein 1 (Ig-PLP1) is an Ig chimera expressing the encephalitogenic PLP1 peptide corresponding to amino acid residues 139–151 of PLP. Newborn mice given Ig-PLP1 in saline on the day of birth and challenged 7 wk later with PLP1 pepti
Autor:
J. Jeremiah Bell, Renu Jain, Hyun-Hee Lee, Randal K. Gregg, Scott J. Schoenleber, Rohit D. Divekar, Habib Zaghouani
Publikováno v:
The Journal of Immunology. 174:662-670
IL-10, a powerful anti-Th1 cytokine, has shown paradoxical effects against diabetes. The mechanism underlying such variable function remains largely undefined. An approach for controlled mobilization of endogenous IL-10 was applied to the NOD mouse a
Autor:
Christopher D. Pack, Lequn Li, Jacque C. Caprio-Young, Booki Min, Aimee E. Cestra, Randal K. Gregg, Habib Zaghouani, Kevin L. Legge, J. Jeremiah Bell
Publikováno v:
The Journal of Immunology. 167:4187-4195
Neonatal exposure to Ag has always been considered suppressive for immunity. Recent investigations, however, indicated that the neonatal immune system could be guided to develop immunity. For instance, delivery of a proteolipid protein (PLP) peptide