Zobrazeno 1 - 10
of 50
pro vyhledávání: '"J. Jefferson P. Perry"'
Autor:
Alissa D. Clear, Glenn M. Manthey, Olivia Lewis, Isabelle Y. Lopez, Rossana Rico, Shannon Owens, M. Cristina Negritto, Elise W. Wolf, Jason Xu, Nikola Kenjić, J. Jefferson P. Perry, Aaron W. Adamson, Susan L. Neuhausen, Adam M. Bailis
Publikováno v:
Microbial Cell, Vol 7, Iss 10, Pp 270-285 (2020)
RAD52 is a structurally and functionally conserved component of the DNA double-strand break (DSB) repair apparatus from budding yeast to humans. We recently showed that expressing the human gene, HsRAD52 in rad52 mutant budding yeast cells can suppre
Externí odkaz:
https://doaj.org/article/84973d6299814b58baf88553703b7a68
Autor:
Caroline M. Li, Pouya Haratipour, Robert G. Lingeman, J. Jefferson P. Perry, Long Gu, Robert J. Hickey, Linda H. Malkas
Publikováno v:
Cells, Vol 10, Iss 11, p 2908 (2021)
Peptides are increasingly being developed for use as therapeutics to treat many ailments, including cancer. Therapeutic peptides have the advantages of target specificity and low toxicity. The anticancer effects of a peptide can be the direct result
Externí odkaz:
https://doaj.org/article/898ac45b5c99412aa0740ae2f675c8b1
Publikováno v:
Biomolecules, Vol 11, Iss 5, p 673 (2021)
Isopeptidase activity of proteases plays critical roles in physiological and pathological processes in living organisms, such as protein stability in cancers and protein activity in infectious diseases. However, the kinetics of protease isopeptidase
Externí odkaz:
https://doaj.org/article/d429b3903c7d4a7c86c8da1e40bacd55
Autor:
J. Jefferson P. Perry, Gregory D. Ballard, Alexandra E. Albert, Lacey E. Dobrolecki, Linda H. Malkas, Derek J. Hoelz
Publikováno v:
Cell Reports, Vol 10, Iss 8, Pp 1288-1296 (2015)
Recent evidence supports the presence of an L-glutamyl methyltransferase(s) in eukaryotic cells, but this enzyme class has been defined only in certain prokaryotic species. Here, we characterize the human C6orf211 gene product as “acidic residue me
Externí odkaz:
https://doaj.org/article/54bf9a26fd9a40c8872d772b1de1cad2
Autor:
Caroline M. Li, Robert G. Lingeman, Pouya Haratipour, Long Gu, Jennifer Jossart, J. Jefferson P. Perry, Robert J. Hickey, Linda H. Malkas
Publikováno v:
Encyclopedia of Cell Biology ISBN: 9780128216248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16d6a4da04cea655122b18eb79f6541a
https://doi.org/10.1016/b978-0-12-821618-7.00195-4
https://doi.org/10.1016/b978-0-12-821618-7.00195-4
Autor:
Parima Udompholkul, Carlo Baggio, Zahra Assar, Aruljothi Muralidharan, Luca Gambini, Nikola Kenjić, J. Jefferson P. Perry, Maurizio Pellecchia
Publikováno v:
J Med Chem
Modulating disease-relevant protein-protein interactions (PPIs) using pharmacological tools is a critical step toward the design of novel therapeutic strategies. Over the years, however, targeting PPIs has proven a very challenging task owing to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4707e2c94611200406322e4dc684cd59
https://doi.org/10.1021/acs.jmedchem.1c00005
https://doi.org/10.1021/acs.jmedchem.1c00005
Autor:
Rossana Rico, Adam M. Bailis, Aaron Adamson, Isabelle Y. Lopez, J. Jefferson P. Perry, M. Cristina Negritto, Olivia Lewis, Jason Xu, Nikola Kenjić, Shannon N Owens, Alissa D. Clear, Susan L. Neuhausen, Elise W. Wolf, Glenn M. Manthey
Publikováno v:
Microbial Cell, Vol 7, Iss 10, Pp 270-285 (2020)
RAD52 is a structurally and functionally conserved component of the DNA double-strand break (DSB) repair apparatus from budding yeast to humans. We recently showed that expressing the human gene, HsRAD52 in rad52 mutant budding yeast cells can suppre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a1a6f64c647269989dd10cced4d536
http://microbialcell.com/researcharticles/2020a-clear-microbial-cell/
http://microbialcell.com/researcharticles/2020a-clear-microbial-cell/
Autor:
Maurizio Pellecchia, J. Jefferson P. Perry, Ahmed F. Salem, Carlo Baggio, Maria Håkansson, Parima Udompholkul, Luca Gambini, Jennifer Jossart
Publikováno v:
Chem Biol Drug Des
Recently, it was reported that tetra-peptides cyclized via lactam bond between the amino terminus and a glutamic residue in position 4 (termed here N-lock) can nucleate helix formation in longer peptides. We applied such strategy to derive N-locked c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d3cd1bb8f67a30a543cf264e9f1a54
https://doi.org/10.1111/cbdd.13661
https://doi.org/10.1111/cbdd.13661
Publikováno v:
Biomolecules
Volume 11
Issue 5
Biomolecules, Vol 11, Iss 673, p 673 (2021)
Volume 11
Issue 5
Biomolecules, Vol 11, Iss 673, p 673 (2021)
Isopeptidase activity of proteases plays critical roles in physiological and pathological processes in living organisms, such as protein stability in cancers and protein activity in infectious diseases. However, the kinetics of protease isopeptidase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::707527b2b0cedaf6b162c1bd0ebae8a6
http://europepmc.org/articles/PMC8145275
http://europepmc.org/articles/PMC8145275
Publikováno v:
Organic Letters. 20:6234-6238
A synthetic strategy for phenolic lipids such as anacardic acid and ginkgolic acid derivatives using an efficient and selective redox-relay Heck reaction followed by a stereoselective olefination is reported. This approach controls both the alkene po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7080d69403e3d08a9faebd1707f455c4
https://doi.org/10.1021/acs.orglett.8b02705
https://doi.org/10.1021/acs.orglett.8b02705