Zobrazeno 1 - 10
of 189
pro vyhledávání: '"J. Jaros"'
Autor:
Kausik K, Ray, Frederick J, Raal, David G, Kallend, Mark J, Jaros, Wolfgang, Koenig, Lawrence A, Leiter, Ulf, Landmesser, Gregory G, Schwartz, David, Lawrence, Andrew, Friedman, Lorena, Garcia Conde, R Scott, Wright
Publikováno v:
European Heart Journal. 44:129-138
Background Inclisiran, an siRNA administered twice-yearly, significantly reduced LDL cholesterol (LDL-C) in Phase III trials. Whether lowering LDL-C with inclisiran translates into a lower risk of cardiovascular (CV) events is not yet established. Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce03820390aa437070e0fe443fecce18
https://doi.org/10.1093/eurheartj/ehac594
https://doi.org/10.1093/eurheartj/ehac594
Autor:
P. Minárik, M. Zemková, S. Šašek, J. Dittrich, M. Knapek, F. Lukáč, D. Koutný, J. Jaroš, R. Král
Publikováno v:
Journal of Magnesium and Alloys, Vol 12, Iss 4, Pp 1496-1510 (2024)
This work explored possibilities of biodegradable magnesium alloy Mg-3Y preparation by two modern powder metallurgy techniques – spark plasma sintering (SPS) and selective laser melting (SLM). The powder material was consolidated by both methods ut
Externí odkaz:
https://doaj.org/article/905050f0a0124ab8b0a1fa1ad4f0f4c1
Autor:
Manal F. Abdelmalek, Margery A. Connelly, Stephen J. Rossi, Mary E. Rinella, Angelo H. Paredes, Stephen A. Harrison, Lei Ling, James F. Trotter, Mark J. Jaros, Alex M. DePaoli
Publikováno v:
Journal of Hepatology. 70:735-744
NGM282, an engineered analogue of the gut hormone FGF19, improves hepatic steatosis and fibrosis biomarkers in patients with non-alcoholic steatohepatitis (NASH). However, NGM282 increases serum cholesterol levels by inhibiting CYP7A1, which encodes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d440475d2f5b9263073de386028c5b92
https://doi.org/10.1016/j.jhep.2018.11.032
https://doi.org/10.1016/j.jhep.2018.11.032
Autor:
Stephen J. Rossi, Mary E. Rinella, Mark J. Jaros, Alex M. DePaoli, Marcelo Kugelmas, Stephen A. Harrison, Manal F. Abdelmalek, Hays Arnold, James F. Trotter, Mustafa R. Bashir, ing L, Angelo H. Paredes, Rohit Loomba
Publikováno v:
The Lancet. 391:1174-1185
Non-alcoholic steatohepatitis is a chronic liver disease characterised by the presence of hepatic steatosis, inflammation, and hepatocellular injury, for which no Food and Drug Administration (FDA)-approved treatment exists. FGF19 is a hormone that r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2cc6150b9c2ebbc26361e35c1f8eb59
https://doi.org/10.1016/s0140-6736(18)30474-4
https://doi.org/10.1016/s0140-6736(18)30474-4
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Abstract The absence of thermalization in certain isolated many-body systems is of great fundamental interest. Many-body localization (MBL) is a widely studied mechanism for thermalization to fail in strongly disordered quantum systems, but it is sti
Externí odkaz:
https://doaj.org/article/646631bfc14348f7a44cda126a8dcbc9
Autor:
F. X. Girod, M. Ungaro, C. Field, G. Kalicy, B. McKinnon, T. K. Nelson, T. Maruyama, A. P. Freyberger, S. Stepanyan, N. A. Baltzell, M. Holtrop, M. Ehrhart, K. Moffeit, S. Uemura, H. Vance, A. Odian, Hovanes Egiyan, R. Paremuzyan, J. Jaros, M. Oriunno, M. Tiefenback
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 859:69-75
The Heavy Photon Search (HPS) is an experiment to search for a hidden sector photon, aka a heavy photon or dark photon, in fixed target electroproduction at the Thomas Jefferson National Accelerator Facility (JLab). The HPS experiment searches for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3afb7d68f7135a2344949c6f00bf8dd
https://doi.org/10.1016/j.nima.2017.03.061
https://doi.org/10.1016/j.nima.2017.03.061
Autor:
William G. Ondo, Ryan Hays, Mansoor Ahmed, Alon Y. Avidan, Mark J. Jaros, Daniel O. Lee, Gwendoline Shang, Mark J. Buchfuhrer, Richard Kim, Diego Garcia-Borreguero
Publikováno v:
Sleep Medicine. 19:50-56
Aim Assess efficacy and tolerability of gabapentin enacarbil (GEn) in adults with severe primary restless legs syndrome (RLS). Methods We pooled data from three 12-week, double-blind, placebo-controlled, randomized trials (NCT00298623, NCT00365352, N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c234461457e8fe5642fdf7d8c303fa4
https://doi.org/10.1016/j.sleep.2015.11.002
https://doi.org/10.1016/j.sleep.2015.11.002
Autor:
A. Spellman, M. Solt, M. Diamond, F. Martinez-Mckinney, O. Moreno, T. Maruyama, Miguel Ullan, D. Bassignana, Marc Christophersen, Randall P. Johnson, C. Bravo, T. K. Nelson, A. Moreno, Matthew J. Graham, J. Jaros, Vitaliy Fadeyev
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 969:163991
We report on design and performance of new strip sensors for the Heavy Photon Search (HPS) experiment. The sensors feature a slim edge implementation using the Scribe–Cleave–Passivate (SCP) method. The slim edge design has allowed the introductio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b54305f2e7ad02b25abc2c684fce4a8
https://doi.org/10.1016/j.nima.2020.163991
https://doi.org/10.1016/j.nima.2020.163991
Autor:
Stephen A. Harrison, Stephen J. Rossi, Lei Ling, Sandra Owers, Rajarshi Banerjee, Bryan Baxter, Mark J. Jaros, James F. Trotter, Cynthia D. Guy, Alex M. DePaoli, Mustafa R. Bashir, Angelo H. Paredes
Publikováno v:
Hepatology (Baltimore, Md.). 71(4)
NGM282, an engineered fibroblast growth factor 19 analogue, rapidly and significantly reduced liver fat content in a multicenter, randomized, double-blind, placebo-controlled study in patients with biopsy-confirmed nonalcoholic steatohepatitis (NASH)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::935d14c5117e0e6dbee577e073be366a
https://pubmed.ncbi.nlm.nih.gov/32118303
https://pubmed.ncbi.nlm.nih.gov/32118303
