ChemoTherapy aNd chemoradioTherapy for adenocarcinoma of the OESophagus and esophagogastric junction with oligometastases: Protocol of the TNT-OES-1 trial

Autor: Charlène J. van der Zijden, Ben M. Eyck, Ate van der Gaast, Leni van Doorn, Joost J.M.E. Nuyttens, J. Jan B. van Lanschot, Bas P.L. Wijnhoven, Bianca Mostert, Sjoerd M. Lagarde

Publikováno v: Contemporary Clinical Trials Communications, Vol 28, Iss , Pp 100934- (2022)

Background: FLOT and CROSS are effective neoadjuvant regimens for esophageal cancer patients. Chemotherapy (FLOT) is aimed to have merely a systemic effect whereas neoadjuvant chemoradiotherapy (CROSS) achieves good locoregional response with clinica

Externí odkaz: https://doaj.org/article/11f5bfb8ec2d439a884eaa7e0d55bd6e

Accuracy of detecting residual disease after neoadjuvant chemoradiotherapy for esophageal squamous cell carcinoma (preSINO trial): a prospective multicenter diagnostic cohort study

Autor: Xiaobin Zhang, Ben M. Eyck, Yang Yang, Jun Liu, Yin-Kai Chao, Ming-Mo Hou, Tsung-Min Hung, Qingsong Pang, Zhen-Tao Yu, Hongjing Jiang, Simon Law, Ian Wong, Ka-On Lam, Berend J. van der Wilk, Ate van der Gaast, Manon C. W. Spaander, Roelf Valkema, Sjoerd M. Lagarde, Bas P. L. Wijnhoven, J. Jan B. van Lanschot, Zhigang Li

Publikováno v: BMC Cancer, Vol 20, Iss 1, Pp 1-11 (2020)

Abstract Background After neoadjuvant chemoradiotherapy (nCRT) for esophageal cancer, high pathologically complete response (pCR) rates are being achieved especially in patients with squamous cell carcinoma (SCC). An active surveillance strategy has

Externí odkaz: https://doaj.org/article/2843509b1b4946d9b515bcdbaadad6c4

Molecular clonality analysis of esophageal adenocarcinoma by multiregion sequencing of tumor samples

Autor: Anna M. J. van Nistelrooij, Ronald van Marion, Linetta B. Koppert, Katharina Biermann, Manon C. W. Spaander, Hugo W. Tilanus, J. Jan B. van Lanschot, Bas P. L. Wijnhoven, Winand N. M. Dinjens

Publikováno v: BMC Research Notes, Vol 10, Iss 1, Pp 1-7 (2017)

Abstract Background Intratumor heterogeneity has been demonstrated in several cancer types, following a model of branched evolution. It is unknown to which extent intratumor heterogeneity is applicable to esophageal adenocarcinoma. Therefore the aim

Externí odkaz: https://doaj.org/article/d45cf8eebed04d518a7c2b0cc21d8731

The effectiveness of neoadjuvant chemoradiotherapy in oesophageal adenocarcinoma with presence of extracellular mucin, signet-ring cells, and/or poorly cohesive cells

Autor: Maria J Valkema, Anne‐Marie Vos, Rachel S van der Post, Ariadne HAG Ooms, Lindsey Oudijk, Ben M Eyck, Sjoerd M Lagarde, Bas PL Wijnhoven, Bastiaan R Klarenbeek, Camiel Rosman, J Jan B van Lanschot, Michail Doukas

Publikováno v: The journal of pathology. Clinical research, 9, 4, pp. 322-335
Journal of Pathology: Clinical Research, 9(4), 322-335. Wiley-Blackwell Publishing Ltd
The journal of pathology. Clinical research, 9, 322-335

Contains fulltext : 293634.pdf (Publisher’s version ) (Open Access) Oesophageal adenocarcinomas may show different histopathological patterns, including excessive acellular mucin pools, signet-ring cells (SRCs), and poorly cohesive cells (PCCs). Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08261eedb94e1d072d752cb0aa4cddaf
https://doi.org/10.1002/cjp2.321

Oesophageal cancer

Autor: Ben M. Eyck, Berend J. van der Wilk, Maurice J.C. van der Sangen, Ate van der Gaast, J. Jan B. van Lanschot

Publikováno v: Oesophagus and Stomach ISBN: 0192863592

Surgery has been the cornerstone of curative treatment for patients with locally advanced oesophageal cancer. Over the last decades, the addition of chemotherapy and radiotherapy to surgery has been extensively tested to improve survival outcomes. Se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::863e63bafc96cb159689703cff677193
https://doi.org/10.1093/med/9780192863591.003.0011