Zobrazeno 1 - 10
of 1 999
pro vyhledávání: '"J. Jaehnig"'
Autor:
Shankha Satpathy, Eric J. Jaehnig, Karsten Krug, Beom-Jun Kim, Alexander B. Saltzman, Doug W. Chan, Kimberly R. Holloway, Meenakshi Anurag, Chen Huang, Purba Singh, Ari Gao, Noel Namai, Yongchao Dou, Bo Wen, Suhas V. Vasaikar, David Mutch, Mark A. Watson, Cynthia Ma, Foluso O. Ademuyiwa, Mothaffar F. Rimawi, Rachel Schiff, Jeremy Hoog, Samuel Jacobs, Anna Malovannaya, Terry Hyslop, Karl R. Clauser, D. R. Mani, Charles M. Perou, George Miles, Bing Zhang, Michael A. Gillette, Steven A. Carr, Matthew J. Ellis
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Connecting genomics and proteomics allows the development of more efficient and specific treatments for cancer. Here, the authors develop proteogenomic methods to defining cancer signaling in-vivo starting from core needle biopsies and with applicati
Externí odkaz:
https://doaj.org/article/1139337b9d47460b818a84e3816a1de9
Autor:
Meenakshi Anurag, Eric J. Jaehnig, Karsten Krug, Jonathan T. Lei, Erik J. Bergstrom, Beom-Jun Kim, Tanmayi D. Vashist, Anh Minh Tran Huynh, Yongchao Dou, Xuxu Gou, Chen Huang, Zhiao Shi, Bo Wen, Viktoriya Korchina, Richard A. Gibbs, Donna M. Muzny, Harshavardhan Doddapaneni, Lacey E. Dobrolecki, Henry Rodriguez, Ana I. Robles, Tara Hiltke, Michael T. Lewis, Julie R. Nangia, Maryam Nemati Shafaee, Shunqiang Li, Ian S. Hagemann, Jeremy Hoog, Bora Lim, C. Kent Osborne, D.R. Mani, Michael A. Gillette, Bing Zhang, Gloria V. Echeverria, George Miles, Mothaffar F. Rimawi, Steven A. Carr, Foluso O. Ademuyiwa, Shankha Satpathy, Matthew J. Ellis
Publikováno v:
Cancer Discovery. 12:2586-2605
Microscaled proteogenomics was deployed to probe the molecular basis for differential response to neoadjuvant carboplatin and docetaxel combination chemotherapy for triple-negative breast cancer (TNBC). Proteomic analyses of pretreatment patient biop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af6d82bb4547e6eb7020e2c5b471b0e
https://doi.org/10.1158/2159-8290.cd-22-0200
https://doi.org/10.1158/2159-8290.cd-22-0200
Autor:
Matthew J. Ellis, Shankha Satpathy, Foluso O. Ademuyiwa, Steven A. Carr, Mothaffar F. Rimawi, George Miles, Gloria V. Echeverria, Bing Zhang, Michael A. Gillette, D.R. Mani, C. Kent Osborne, Bora Lim, Jeremy Hoog, Ian S. Hagemann, Shunqiang Li, Maryam Nemati Shafaee, Julie R. Nangia, Michael T. Lewis, Tara Hiltke, Ana I. Robles, Henry Rodriguez, Lacey E. Dobrolecki, Harshavardhan Doddapaneni, Donna M. Muzny, Richard A. Gibbs, Viktoriya Korchina, Bo Wen, Zhiao Shi, Chen Huang, Xuxu Gou, Yongchao Dou, Anh Minh Tran Huynh, Tanmayi D. Vashist, Beom-Jun Kim, Erik J. Bergstrom, Jonathan T. Lei, Karsten Krug, Eric J. Jaehnig, Meenakshi Anurag
Microscaled proteogenomics was deployed to probe the molecular basis for differential response to neoadjuvant carboplatin and docetaxel combination chemotherapy for triple-negative breast cancer (TNBC). Proteomic analyses of pretreatment patient biop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2213f3db6710d869c1c4f3f803aa9523
https://doi.org/10.1158/2159-8290.c.6549759.v1
https://doi.org/10.1158/2159-8290.c.6549759.v1
Autor:
Matthew J. Ellis, Shankha Satpathy, Foluso O. Ademuyiwa, Steven A. Carr, Mothaffar F. Rimawi, George Miles, Gloria V. Echeverria, Bing Zhang, Michael A. Gillette, D.R. Mani, C. Kent Osborne, Bora Lim, Jeremy Hoog, Ian S. Hagemann, Shunqiang Li, Maryam Nemati Shafaee, Julie R. Nangia, Michael T. Lewis, Tara Hiltke, Ana I. Robles, Henry Rodriguez, Lacey E. Dobrolecki, Harshavardhan Doddapaneni, Donna M. Muzny, Richard A. Gibbs, Viktoriya Korchina, Bo Wen, Zhiao Shi, Chen Huang, Xuxu Gou, Yongchao Dou, Anh Minh Tran Huynh, Tanmayi D. Vashist, Beom-Jun Kim, Erik J. Bergstrom, Jonathan T. Lei, Karsten Krug, Eric J. Jaehnig, Meenakshi Anurag
Supplementary Figure from Proteogenomic Markers of Chemotherapy Resistance and Response in Triple-Negative Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cddd49408408cb8699c178559bdada3
https://doi.org/10.1158/2159-8290.22541898
https://doi.org/10.1158/2159-8290.22541898
Autor:
Matthew J. Ellis, Shankha Satpathy, Foluso O. Ademuyiwa, Steven A. Carr, Mothaffar F. Rimawi, George Miles, Gloria V. Echeverria, Bing Zhang, Michael A. Gillette, D.R. Mani, C. Kent Osborne, Bora Lim, Jeremy Hoog, Ian S. Hagemann, Shunqiang Li, Maryam Nemati Shafaee, Julie R. Nangia, Michael T. Lewis, Tara Hiltke, Ana I. Robles, Henry Rodriguez, Lacey E. Dobrolecki, Harshavardhan Doddapaneni, Donna M. Muzny, Richard A. Gibbs, Viktoriya Korchina, Bo Wen, Zhiao Shi, Chen Huang, Xuxu Gou, Yongchao Dou, Anh Minh Tran Huynh, Tanmayi D. Vashist, Beom-Jun Kim, Erik J. Bergstrom, Jonathan T. Lei, Karsten Krug, Eric J. Jaehnig, Meenakshi Anurag
Supplementary Table from Proteogenomic Markers of Chemotherapy Resistance and Response in Triple-Negative Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aaa3ac19a23458641597347d9d61321
https://doi.org/10.1158/2159-8290.22541895
https://doi.org/10.1158/2159-8290.22541895
Publikováno v:
Bioinformatics. 38:5463-5465
Summary RNA-Seq and mass spectrometry-based studies generate omics data tables with measurements for tens of thousands of genes across all samples in a study. The success of a study relies on the quality of these data tables, which is determined by b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64171e81989abebcaea7283824a83ab1
https://doi.org/10.1093/bioinformatics/btac698
https://doi.org/10.1093/bioinformatics/btac698
Autor:
Xinpei Yi, Bo Wen, Shuyi Ji, Alex Saltzman, Eric J. Jaehnig, Jonathan T. Lei, Qiang Gao, Bing Zhang
Publikováno v:
bioRxiv
Shotgun phosphoproteomics enables high-throughput analysis of phosphopeptides in biological samples, but low phosphopeptide identification rate in data analysis limits the potential of this technology. Here we present DeepRescore2, a computational wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac96826280bc3ed026741b6035dca30
https://doi.org/10.1101/2023.01.11.523329
https://doi.org/10.1101/2023.01.11.523329
Publikováno v:
Cancer Research. 83:1460-1460
Introduction: According to the American Cancer Society, An estimated 2,710 men are diagnosed with breast cancer annually of which about 530 die due to the disease annually in the United States. Most male breast tumors are estrogen receptor positive.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c6c358c2e51c572e3efac0a58bf2e83
https://doi.org/10.1158/1538-7445.am2023-1460
https://doi.org/10.1158/1538-7445.am2023-1460
Autor:
Alexander B Saltzman, Doug W Chan, Matthew V Holt, Junkai Wang, Eric J Jaehnig, Meenakshi Anurag, Purba Singh, Anna Malovannaya, Beom-Jun Kim, Matthew J Ellis
Protein kinases are frequently dysregulated and/or mutated in cancer and represent essential targets for therapy. Accurate quantification is essential, but current approaches are inadequate. For breast cancer treatment for example, the identification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fde3a5aee548629fae6c634adb8b22b5
https://doi.org/10.1101/2022.10.13.511593
https://doi.org/10.1101/2022.10.13.511593
Autor:
Eric J. Jaehnig, Aranzazu Fernandez-Martinez, Tanmayi Vashist, Matthew V. Holt, LaTerrica Williams, Jonathan Lei, Beom-Jun Kim, Yongchao Dou, Viktoriya Korchina, Richard Gibbs, Donna Muzny, Harshavardhan Doddapaneni, Henry Rodriguez, Ana Robles, Tara Hiltke, DR Mani, Michael Gillette, Terry Hyslop, Yujia Wen, Linda McCart, George Miles, Steven Carr, Bing Zhang, Shankha Satpathy, Matthew Ellis, Meenakshi Anurag
Publikováno v:
Cancer Research. 83:P5-02
Background: Targeted therapy for HER2+ breast cancer has significantly improved outcomes for this aggressive subtype. However, a subset of patients do not achieve pathological complete response (pCR). In CALGB 40601, a randomized Phase III Trial for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d08c2472c755bdbd5f659f741b62884
https://doi.org/10.1158/1538-7445.sabcs22-p5-02-36
https://doi.org/10.1158/1538-7445.sabcs22-p5-02-36