Safety and Clinical Outcomes of Using Low–Molecular-Weight Dextran During Islet Autotransplantation in Children

Autor: Elise F. Northup, Srinath Chinnakotla, Hawa M. Ali, Alexander A. Boucher, Ellen R. Florek, J. J. Wilhelm, Melena D. Bellin, Sarah Jane Schwarzenberg, Elissa M. Downs

Publikováno v: Pancreas. 49:774-780

OBJECTIVES The objective of this study was to evaluate potential safety and clinical benefit of low-molecular-weight dextran (dextran) use in patients undergoing total pancreatectomy with islet auto transplantation (TPIAT). METHODS We evaluated 124 c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5760f561c196b89136f90f2c1a4641
https://doi.org/10.1097/mpa.0000000000001571

Purified Human Pancreatic Islets, CIT Culture Media with Lisofylline or Exenatide

Autor: J, Ansite, A N, Balamurugan, B, Barbaro, J, Battle, D, Brandhorst, J, Cano, X, Chen, S, Deng, D, Feddersen, A, Friberg, T, Gilmore, J S, Goldstein, E, Holbrook, A, Khan, T, Kin, J, Lei, E, Linetsky, C, Liu, X, Luo, K, McElvaney, Z, Min, J, Moreno, D, O'Gorman, K K, Papas, G, Putz, C, Ricordi, G, Szot, T, Templeton, L, Wang, J J, Wilhelm, J, Willits, T, Wilson, X, Zhang, J, Avila, B, Begley, S, Carpentier, J, Hutchinson, C P, Larsen, M, Sears, N A, Turgeon, D, Webster, J F, Markmann, N D, Bridges, C W, Czarniecki, T L, Eggerman, P, Al-Saden, A, Hecyk, H, Kissler, M, Molitch, N, Monson, E, Stuart, A, Wallia, S, Wang, D, Bigam, P, Campbell, P, Dinyari, N, Kneteman, J, Lyon, A, Malcolm, C, Onderka, R, Owen, R, Pawlick, B, Richer, S, Rosichuk, D, Sarman, A, Schroeder, P A, Senior, A M J, Shapiro, L, Toth, V, Toth, W, Zhai, K, Johnson, J, McElroy, A M, Posselt, M, Ramos, T, Rojas, P G, Stock, J, Martellotto, J, Oberholzer, M, Qi, Y, Wang, L, Bayman, K, Chaloner, W, Clarke, J S, Dillon, C, Diltz, G C, Doelle, D, Ecklund, E, Foster, L G, Hunsicker, C, Jasperson, D-E, Lafontant, T, Neill-Hudson, D, Nollen, J, Qidwai, H, Riss, T, Schwieger, J, Yankey, R, Alejandro, A C, Corrales, R, Faradji, T, Froud, A A, Garcia, E, Herrada, H, Ichii, L, Inverardi, N, Kenyon, J, Montelongo, E, Peixoto, K, Peterson, J, Szust, X, Wang, M H, Abdulla, M D, Bellin, M, Brandenburg, J V, Harmon, B J, Hering, R, Kandaswamy, G, Loganathan, K, Mueller, J, Pedersen, J, Witson, C, Dalton-Bakes, H, Fu, M, Kamoun, J, Kearns, Y, Li, E, Luning-Prak, Y, Luo, E, Markmann, A, Naji, M, Palanjian, M, Rickels, R, Shlansky-Goldberg, K, Vivek, A S, Ziaie, L, Fernandez, D B, Kaufman, L, Zitur, O, Korsgren

Publikováno v: CellR4-- repair, replacement, regeneration,reprogramming. 5(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b6b0b9f3f53cdf8feea82fe5c36a5faa
https://pubmed.ncbi.nlm.nih.gov/30613755

Total Pancreatectomy and Islet Autotransplantation in Children for Chronic Pancreatitis

Autor: Melena D. Bellin, Selwyn M. Vickers, J. J. Wilhelm, Martin L. Freeman, Ty B. Dunn, Gregory J. Beilman, Appakalai N. Balamurugan, Timothy L. Pruett, Bernhard J. Hering, Jose M. Jimenez-Vega, Sarah Jane Schwarzenberg, David M. Radosevich, Srinath Chinnakotla, Barbara Bland, David E.R. Sutherland, Marie Cook

Publikováno v: Annals of Surgery. 260:56-64

Describe the surgical technique, complications, and long-term outcomes of total pancreatectomy and islet autotransplantation (TP-IAT) in a large series of pediatric patients.Surgical management of childhood pancreatitis is not clear; partial resectio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21d14abbc8c32e2ad470a37851d5b6d
https://doi.org/10.1097/sla.0000000000000569

Predicting β-Cell Mass in Pediatric Islet Autotransplantation Patients

Autor: Srinath Chinnakotla, Mariya E. Skube, Sarah Jane Schwarzenberg, Greg J. Beilman, Daniel A. Saltzman, J. J. Wilhelm, Melena D. Bellin

Publikováno v: Journal of the American College of Surgeons. 227:S254

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::957b44f59654dbc9fbb7812f8e97b47f
https://doi.org/10.1016/j.jamcollsurg.2018.07.521

Islet Oxygen Consumption Rate (OCR) Dose Predicts Insulin Independence in Clinical Islet Autotransplantation

Autor: Joyce C. Niland, E. S. Avgoustiniatos, Angelika C. Gruessner, Kathryn R. Mueller, Clark K. Colton, David E.R. Sutherland, Thomas M. Suszynski, Melena D. Bellin, Gopalakrishnan Loganathan, Dajun Qian, Klearchos K. Papas, J. J. Wilhelm, Bernhard J. Hering, Gregory J. Beilman, Jennifer P. Kitzmann, Maria Koulmanda, Gordon C. Weir, Appakalai N. Balamurugan

Publikováno v: PLoS ONE, Vol 10, Iss 8, p e0134428 (2015)
PLoS ONE
Public Library of Science

Background Reliable in vitro islet quality assessment assays that can be performed routinely, prospectively, and are able to predict clinical transplant outcomes are needed. In this paper we present data on the utility of an assay based on cellular o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e9a216a2aa8274b23dc27b697f6fac
https://doi.org/10.1371/journal.pone.0134428