Výsledky vyhledávání - "J. J. T. M. Heuvel"

GATA transcription factors in testicular adrenal rest tumours

Autor: Rod T. Mitchell, Fred C.G.J. Sweep, J. J. T. M. Heuvel, Nike M. M. L. Stikkelbroeck, Monica A.J. Marijnissen-van Zanten, Hedi L Claahsen-van der Grinten, Paul N. Span, Antonius E. van Herwaarden, Christina A. Hulsbergen-van de Kaa, Manon Engels, Egbert Oosterwijk, Lee B. Smith

Publikováno v: Endocrine Connections, 6, 8, pp. 866-875
Endocrine Connections, Vol 6, Iss 8, Pp 866-875 (2017)
Endocrine Connections, 6, 866-875
Endocrine Connections
Engels, M, Span, P N, Mitchell, R T, Heuvel, J J T M, Marijnissen-van Zanten, M A, van Herwaarden, A E, Hulsbergen-van de Kaa, C A, Oosterwijk, E, Stikkelbroeck, N M, Smith, L B, Sweep, F C G J & Claahsen-van der Grinten, H L 2017, ' GATA transcription factors in testicular adrenal rest tumours ', Endocrine connections . https://doi.org/10.1530/EC-17-0215

Testicular adrenal rest tumours (TARTs) are benign adrenal-like testicular tumours that frequently occur in male patients with congenital adrenal hyperplasia. Recently, GATA transcription factors have been linked to the development of TARTs in mice.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9cc3dec6a402460457f266ec5c2ef5d
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/181619

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Do the survivin (BIRC5) splice variants modulate or add to the prognostic value of total survivin in breast cancer?

Autor: Vivianne C. G. Tjan-Heijnen, Paul N. Span, Fred C.G.J. Sweep, Jacques B. de Kok, J. J. T. M. Heuvel, John A. Foekens

Publikováno v: Clinical Chemistry, 52, 1693-700
Clinical Chemistry, 52(9), 1693-1700. American Association for Clinical Chemistry Inc.
Clinical Chemistry, 52, 9, pp. 1693-700

Background: A total of 4 additional splice variants (survivin-ΔEx3, survivin 2α, survivin-2B, and survivin-3B) have been described for survivin [baculoviral IAP repeat-containing protein (BIRC-5), approved gene symbol BIRC5], which has been implica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::968f5a26560682fca684e4be6d3105c7
https://hdl.handle.net/1765/55543

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Mammaglobin is associated with low-grade, steroid receptor-positive breast tumors from postmenopausal patients, and has independent prognostic value for relapse-free survival time

Autor: Peggy Manders, Paul N. Span, Fred C.G.J. Sweep, J. J. T. M. Heuvel, John A. Foekens, Mark A. Watson, Esmé Waanders, Louk V.A.M. Beex

Publikováno v: Journal of Clinical Oncology, 22, 691-8
Journal of Clinical Oncology, 22, 4, pp. 691-8

Purpose The tumor mRNA expression levels of mammaglobin, a novel breast-specific and breast cancer-associated marker, were correlated with disease outcome in 280 patients with primary breast cancer. Patients and Methods Mammaglobin expression levels

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a17e57147f4d45c406db3ea8a4628e
https://doi.org/10.1200/JCO.2004.01.072

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Molecular Beacon Reverse Transcription-PCR of Human Chorionic Gonadotropin-β-3, -5, and -8 mRNAs Has Prognostic Value in Breast Cancer

Autor: Paul N. Span, J. J. T. M. Heuvel, Remko R. Bosch, C.G.J. Sweep, Louk V.A.M. Beex, Chris M.G. Thomas, Peggy Manders

Publikováno v: Clinical Chemistry, 49, 1074-80
Clinical Chemistry, 49, 7, pp. 1074-80

Background: The β-subunit of human chorionic gonadotropin (hCG) is encoded by four genes, of which expression of the hCGβ-3, -5, and -8 genes could have prognostic value in breast cancer.Methods: Applying a new, modified Molecular Beacon reverse tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a0181ce1472f0f6cdfbf3f544ceaad8
https://doi.org/10.1373/49.7.1074

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Expression of the transcription factor Ets-1 is an independent prognostic marker for relapse-free survival in breast cancer

Autor: J. J. T. M. Heuvel, Paul N. Span, Chris M.G. Thomas, Remko R. Bosch, Louk V.A.M. Beex, Peggy Manders, C.G.J. Sweep

Publikováno v: Oncogene, 21, 8506-9
Oncogene, 21, 55, pp. 8506-9

Item does not contain fulltext The transcription factor Ets-1 regulates the expression of several angiogenic and extracellular matrix remodeling factors, and might be implicated in disease progression of breast cancer. In the present study, the progn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7092bf2cdd7df4ac012e569795043022
https://doi.org/10.1038/sj.onc.1206040

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Analysis of expression of chorionic gonadotrophin transcripts in prostate cancer by quantitative Taqman and a modified molecular beacon RT-PCR

Autor: C.G.J. Sweep, Jack A. Schalken, Paul N. Span, J. J. T. M. Heuvel, A.T.F. van de Locht, Remko R. Bosch, Ewald J.B.M. Mensink, Chris M.G. Thomas

Publikováno v: Journal of Endocrinology, 172, 3, pp. 489-95
Journal of Endocrinology, 172, 489-95

Item does not contain fulltext Expression of human chorionic gonadotrophin (hCG) is associated with trophoblastic, testicular and other malignancies such as bladder, pancreatic, cervical, breast and prostate cancer. In the prostate, however, hCG expr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5900033e6457d3f9351be12a7fe0f64c
https://hdl.handle.net/2066/123550

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Prognostic value of tissue-type plasminogen activator (tPA) and its complex with the type-1 inhibitor (PAI-1) in breast cancer

Autor: C.G.J. Sweep, J.G.M. Klijn, Maxime P. Look, J.A. Foekens, J Bolt-de Vries, N. Grebenschikov, T. H. Van Tienoven, J.H. de Witte, J. J. T. M. Heuvel, Th.J. Benraad, H. A. Peters

Publikováno v: British Journal of Cancer, 80, 1/2, pp. 286-294
ResearcherID
British Journal of Cancer
British Journal of Cancer, 80(1/2), 286-294. Nature Publishing Group
British Journal of Cancer, 80, 286-294

The prognostic value of tissue-type plasminogen activator (tPA) measured in samples derived from 865 patients with primary breast cancer using a recently developed enzyme-linked immunosorbent assay (ELISA) was evaluated. Since the assay could easily

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c53baa4a76cea05cbdf5ac7b8cb1dd60
https://hdl.handle.net/2066/184848

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Prognostic impact of urokinase-type plasminogen activator (uPA) and its inhibitor (PAI-1) in cytosols and pellet extracts derived from 892 breast cancer patients

Autor: Maxime P. Look, J.G.M. Klijn, Th.J. Benraad, C.G.J. Sweep, H. A. Peters, N. Grebenschikov, J.A. Foekens, J.H. de Witte, J. J. T. M. Heuvel, Th H van Tienoven, W. L. J. Van Putten

Publikováno v: British Journal of Cancer, 79, 7/8, pp. 1190-1198
British Journal of Cancer
British Journal of Cancer, 79(7/8), 1190-1198. Nature Publishing Group
British Journal of Cancer, 79, 1190-1198

To evaluate the clinical relevance of urokinase-type plasminogen activator (uPA) and its type-1 inhibitor (PAI-1) measured by a recently developed enzyme-linked immunosorbent assay (ELISA), we analysed both components in samples derived from 892 pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f46a1c7e7b0035d9802bd00c7ae37e5
https://doi.org/10.1038/sj.bjc.6690191

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