Zobrazeno 1 - 10
of 25
pro vyhledávání: '"J. J. Stegeman"'
Autor:
Siddavaram Nagini, Y. Hara, J. J. Stegeman, K.V.P. Chandra Mohan, P. Vidjaya Letchoumy, H. V. Gelboin
Publikováno v:
Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics. 17:193-203
The present study was designed to evaluate the in vitro antioxidant potential of bovine lactoferrin (bLF) and black tea polyphenols [Polyphenon-B (P-B)] as well as in vivo inhibitory effects on the development of 7,12-dimethylbenz[a]anthracene (DMBA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de3ca647036fdbb4c9d140b82b60ad7
https://doi.org/10.3727/096504008786111365
https://doi.org/10.3727/096504008786111365
Autor:
J. J. Stegeman, Y. Hara, P. Vidjaya Letchoumy, H. V. Gelboin, Siddavaram Nagini, K.V.P. Chandra Mohan
The objective of this study was to evaluate the chemopreventive potential of the black tea polyphenols Polyphenon-B and BTF-35 during the preinitiation phase of 7,12-dimethylbenz[a]anthracene (DMBA)-induced hamster buccal pouch (HBP) carcinogenesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb286414fdf5b1e8348a44b3485c0cf1
https://europepmc.org/articles/PMC3974168/
https://europepmc.org/articles/PMC3974168/
Publikováno v:
Environmental toxicology and chemistry. 20(1)
Monoclonal antibody 1-12-3 (MAb 1-12-3) recognizes an epitope exclusive to cytochrome P450s in subfamily 1A (CYP1A) from all vertebrates tested so far, including one amphibian species. In this study, we first tested the utility of MAb 1-12-3 for dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db1b06f9cefcf4540dc3e9b1d2da16d9
https://pubmed.ncbi.nlm.nih.gov/11351408
https://pubmed.ncbi.nlm.nih.gov/11351408
Autor:
J J, Schlezinger, J J, Stegeman
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 28(6)
Endothelium is a common site of cytochrome P450 1A (CYP1A) induction in vertebrates, and endothelial CYP1A could affect the distribution and toxicity of CYP1A substrates. We investigated CYP1A induction in organs rich in endothelium, gill, heart, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47d608fa67b4733857ceb6a250ccce16
https://pubmed.ncbi.nlm.nih.gov/10820144
https://pubmed.ncbi.nlm.nih.gov/10820144
Autor:
J J, Stegeman, D R, Livingstone
Publikováno v:
Comparative biochemistry and physiology. Part C, Pharmacology, toxicologyendocrinology. 121(1-3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4a37a5b297fe3464fadcf4e18570edcc
https://pubmed.ncbi.nlm.nih.gov/9972446
https://pubmed.ncbi.nlm.nih.gov/9972446
Publikováno v:
Comparative biochemistry and physiology. Part C, Pharmacology, toxicologyendocrinology. 120(1)
The mammalian aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that controls the expression of cytochrome P450 1A (CYP1A) genes in response to halogenated aromatic hydrocarbons such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c6ed5364a2a3961fb7c1ea1572bc5d50
https://pubmed.ncbi.nlm.nih.gov/9827018
https://pubmed.ncbi.nlm.nih.gov/9827018
Publikováno v:
Toxicology and applied pharmacology. 141(1)
Concentration-dependent effects of halogenated aromatic hydrocarbons (HAHs) on cytochrome P4501A (CYP1A) induction in primary hepatocyte cultures prepared from embryos of chickens (four breeds), pheasants, turkeys, ducks (three breeds), and herring g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3524151bfc98b26adc19ca31ce2d4274
https://pubmed.ncbi.nlm.nih.gov/8917694
https://pubmed.ncbi.nlm.nih.gov/8917694
Autor:
P J, Kloepper-Sams, J J, Stegeman
Publikováno v:
Molecular marine biology and biotechnology. 3(3)
Earlier studies showed that in Fundulus heteroclitus liver, the content of microsomal cytochrome P4501A (CYP1A) protein induced by beta-naphthoflavone is elevated for weeks after its induction, whereas the content of the induced CYP1A mRNA peaks and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::10e2f9d99ed41a89a49aecff5d2cb843
https://pubmed.ncbi.nlm.nih.gov/7921047
https://pubmed.ncbi.nlm.nih.gov/7921047
Publikováno v:
Cancer research. 53(16)
Monoclonal antibody 1-12-3 reactive against scup (Stenotomus chrysops) cytochrome P450 E (a teleost CYP IA1) has been used to immunohistochemically localize CYP IA1 within hepatocytes and presumably sinusoidal endothelial and biliary epithelial cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::948464d5551551a9a80d26e996ab5f4c
https://pubmed.ncbi.nlm.nih.gov/8339279
https://pubmed.ncbi.nlm.nih.gov/8339279
Autor:
J. J. Stegeman
Publikováno v:
Cytochrome P450 ISBN: 9783642777653
Recognition that cytochromes P450 play key roles in pharmacology, toxicology, carcinogenesis and endocrinology stimulated the drive to understand the diversity of forms, functions and regulation of these enzymes. Comparative biochemistry has played a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb272e86760193422b3a3dd9f4620159
https://doi.org/10.1007/978-3-642-77763-9_18
https://doi.org/10.1007/978-3-642-77763-9_18