Zobrazeno 1 - 10
of 25
pro vyhledávání: '"J. J. Sedmak"'
Publikováno v:
Cancer research. 52(18)
The use of bacterial exotoxins may constitute novel adjuncts to treatment of gastrointestinal tract malignancies. Clostridium difficile toxin A was evaluated for its cytotoxic effect in vitro on 24 human cell lines and strains including carcinomas of
Publikováno v:
Cytobios. 64(258-259)
The major change in the ultrastructure of Chinese hamster ovary (CHO) cells treated with Clostridium difficile enterotoxin A was the formation of bundles of filaments in the nucleoplasm. The filaments appeared after 2.5 h and disappeared by the fourt
Publikováno v:
Journal of General Virology. 35:45-52
Altering the aqueous environment, especially with agents that affect hydrogen bonds, markedly affects the stability of mouse L cell interferon. Low pH stabilizes interferon whereas high pH labilizes it; heavy water further enhances interferon thermos
Publikováno v:
Cytobios. 53(214-215)
The dynamics of internalization and transport of murine interferon-beta (MuIFN-beta) to the cell nucleus was studied in cultured L929 mouse fibroblasts employing postembedding, ultrastructural quantitative immunocytochemistry. Cells preincubated with
Publikováno v:
In vitro. Monograph. (3)
Publikováno v:
Interferons and Their Applications ISBN: 9783642691805
The definition of interferon (IFN) as a cellular protein capable of making cultured cells resistant to virus infection depends upon a biologic assay. The purpose of the assay is to determine biologic activity, or potency, in ways comparable to what h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e21475d3f12adea6160bf22b98aa8164
https://doi.org/10.1007/978-3-642-69178-2_2
https://doi.org/10.1007/978-3-642-69178-2_2
Publikováno v:
Cancer research. 45(11 Pt 1)
We examined the effect of human interferon (HuIFN) -alpha and -beta on the proliferation and differentiation induced by dimethyl sulfoxide (DMSO) of HL-60 human promyelocytic leukemia cells into mature granulocytes. Neither HuIFN-alpha nor -beta, alo
Publikováno v:
Cytobios. 54(218-219)
Postembedding immunogold staining was used to quantify low numbers of intracytoplasmic cytokine interferon molecules in cells embedded in Lowicryl K4M by the rapid technique of Altman et al. (1984). When labelling with colloidal gold-protein A (CGPA)
Publikováno v:
Cytobios. 41(161)
Diphtheria toxin (DT) receptor sites were identified on cell membranes by indirect immunofluorescence and immunoferritin labelling. The results obtained were correlated (1) with the binding of 125I-labelled DT (to the very same cell populations used
Autor:
J J, Sedmak, S E, Grossberg
Publikováno v:
Texas reports on biology and medicine. 35
It is now obvious that there are a number of factors which can influence the stability of interferons. Since human fibroblast interferon is especially unstable both to heat and mechanical stress, the use of stabilizing conditions such as low pH or th