Zobrazeno 1 - 10
of 31
pro vyhledávání: '"J. J. Onorato"'
Publikováno v:
Journal of Biological Chemistry. 269:1099-1105
G protein-coupled receptor kinases (GRKs) such as rhodopsin kinase and the beta-adrenergic receptor kinase (beta ARK) play an important role in agonist-specific phosphorylation and desensitization of G protein-coupled receptors. GRK5 is a recently id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33e8d2b77d4965c664a7364d98d03ecf
https://doi.org/10.1016/s0021-9258(17)42226-5
https://doi.org/10.1016/s0021-9258(17)42226-5
Autor:
Nancy A. Jenkins, Neal G. Copeland, J. L. Benovic, Martin J. Lohse, J. L. Arriza, J. J. Onorato, Marc G. Caron, Robert J. Lefkowitz, D. J. Gilbert, W. C. Stone
Publikováno v:
Journal of Biological Chemistry. 266:14939-14946
The beta-adrenergic receptor kinase (beta ARK) specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Structural features of this enzyme have been elucidated recently by the isolation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae987411c6423a9080c972d663b3ad17
https://doi.org/10.1016/s0021-9258(18)98568-6
https://doi.org/10.1016/s0021-9258(18)98568-6
Publikováno v:
Canadian journal of physiology and pharmacology. 76(2)
We examined the effects of the muscarinic agonist carbachol on ion secretion induced by substance P (SP) in piglet jejunal tissues mounted in Ussing chambers. Tetrodotoxin was present in all solutions to inhibit neural activity. Carbachol added 10 mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa7f49618ff72af7b2aeb3731776d6cf
https://pubmed.ncbi.nlm.nih.gov/9635156
https://pubmed.ncbi.nlm.nih.gov/9635156
Autor:
V V, Gurevich, S B, Dion, J J, Onorato, J, Ptasienski, C M, Kim, R, Sterne-Marr, M M, Hosey, J L, Benovic
Publikováno v:
The Journal of biological chemistry. 270(2)
Arrestins play an important role in quenching signal transduction initiated by G protein-coupled receptors. To explore the specificity of arrestin-receptor interaction, we have characterized the ability of various wild-type arrestins to bind to rhodo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75dab098469e7c802e7086028571d62b
https://pubmed.ncbi.nlm.nih.gov/7822302
https://pubmed.ncbi.nlm.nih.gov/7822302
Publikováno v:
The Journal of biological chemistry. 269(2)
G protein-coupled receptor kinases (GRKs) such as rhodopsin kinase and the beta-adrenergic receptor kinase (beta ARK) play an important role in agonist-specific phosphorylation and desensitization of G protein-coupled receptors. GRK5 is a recently id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8419b4aee5290c83b5087badfbf604e
https://pubmed.ncbi.nlm.nih.gov/8288567
https://pubmed.ncbi.nlm.nih.gov/8288567
Publikováno v:
The Biochemical journal. 292
The aqueous two-phase partition technique is a simple, rapid and inexpensive method for the fractionation of membrane preparations. Aqueous two-phase partitioning separates according to surface properties such as charge and hydrophobicity, making it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee72a9cf112756481790c79d0dfa15b1
https://pubmed.ncbi.nlm.nih.gov/7686365
https://pubmed.ncbi.nlm.nih.gov/7686365
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 264(2)
Renal thromboxane (Tx) production is increased in the MRL-lpr murine model of lupus nephritis. To investigate the relationship between increased Tx production and number and affinity of Tx receptors, we measured binding of the Tx receptor antagonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f789f45af724da44436cd46b31c4018
https://pubmed.ncbi.nlm.nih.gov/8437109
https://pubmed.ncbi.nlm.nih.gov/8437109
Publikováno v:
Receptor. 3(1)
The beta-adrenergic receptor kinases, beta ARK1 and beta ARK2, are two recently cloned members of the G protein-coupled receptor kinase family. To further characterize these kinases, bovine beta ARK1 and beta ARK2 have been overexpressed in Sf9 insec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f77c2d3a0f11218ce7c7f7be6a6218a
https://pubmed.ncbi.nlm.nih.gov/8394172
https://pubmed.ncbi.nlm.nih.gov/8394172
Publikováno v:
American Journal of Physiology-Renal Physiology. 257:F631-F638
Phosphate uptake by proximal renal cells derived from the human kidney occurs by a saturable process that is approximately 85% dependent on the presence of sodium. Kinetic analysis is consistent with two distinct transport events with Km of 0.08 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c9c46fcaf5a6af46c78eb4c24f777b
https://doi.org/10.1152/ajprenal.1989.257.4.f631
https://doi.org/10.1152/ajprenal.1989.257.4.f631
Autor:
J J, Onorato, S A, Rudolph
Publikováno v:
The Journal of biological chemistry. 256(20)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::56db6b913e3192e05e5117e16c3cc680
https://pubmed.ncbi.nlm.nih.gov/6169722
https://pubmed.ncbi.nlm.nih.gov/6169722