Zobrazeno 1 - 10
of 25
pro vyhledávání: '"J. J. Hjelle"'
Publikováno v:
Advances in experimental medicine and biology. 284
Publikováno v:
Enzymology and Molecular Biology of Carbonyl Metabolism 3 ISBN: 9781468459036
Peroxidation of membrane lipids is thought be a dynamic process which is ongoing in virtually all cells. Under normal conditions, cellular lipid peroxidation is well regulated and, as noted in a recent review (Esterbauer. et al. , 1990), is always as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::914ac698fcb2275280df81fdbb6b413a
https://doi.org/10.1007/978-1-4684-5901-2_9
https://doi.org/10.1007/978-1-4684-5901-2_9
Publikováno v:
Alcoholism: Clinical and Experimental Research. 5:198-203
Male mice selected for genetic differences in ethanol-induced sleep time, thereby designated long sleep (LS) an short sleep (SS), were treated with the Lieber-DeCarli liquid diet for 25 days. This chronic ethanol treatment produced an increase in liv
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 221(2)
A single injection of ethanol was shown to produce a relatively rapid increase in the in vitro activity of aniline hydroxylase and in microsomal ethanol oxidation. Stimulation of the microsomal ethanol oxidating system (MEOS) was dependent on the eth
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 13(1)
The purpose of this investigation was to determine the effects of acute administration of acetaminophen on adenosine 3'-phosphate 5'-phosphosulfate (PAPS) and UDP-glucuronic acid concentrations in fed male rats. Acetaminophen produced a dosage-depend
Publikováno v:
Toxicology and applied pharmacology. 83(3)
The present study examined the effects of butylated hydroxyanisole (BHA) on acetaminophen-induced hepatotoxicity and metabolism in vivo with emphasis on possible changes in the glucuronidation pathway. Female Swiss-Webster mice received BHA in the di
Autor:
P A, McAnulty, M J, Collier, J, Enticott, J M, Tesh, D A, Mayhew, C P, Comer, J J, Hjelle, F N, Kotsonis
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 13(2)
Aspartame (L-aspartyl-L-phenylalanine methyl ester) is a widely used high potency dipeptide sweetener. Developmental toxicology studies have been performed in several species documenting no effects of high doses of aspartame. Recently, a study by Mah
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 5(5)
Endogenous sulfhydryl compounds serve a critical role in maintaining the function and viability of living systems. Glutathione (GSH) is the most abundant of these nonprotein thiols. During the past decade it has been demonstrated that sulfhydryls suc
Autor:
D R, Petersen, J J, Hjelle
Publikováno v:
Progress in clinical and biological research. 114
The specific physiological roles of ALDH have not been determined. In this overview, we have identified malondialdehyde as one potential endogenous toxic aldehyde that is oxidized by ALDH. Undoubtedly, there are other cytotoxic aldehydes which occur