Zobrazeno 1 - 5
of 5
pro vyhledávání: '"J. J. David Ho"'
Autor:
Nathan C. Balukoff, J. J. David Ho, Phaedra R. Theodoridis, Miling Wang, Michael Bokros, Lis M. Llanio, Jonathan R. Krieger, Jonathan H. Schatz, Stephen Lee
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Translatome remodelling controls stress-adaptive protein output. Here the authors reveal that in response to stimuli, eIF5A functions as a pH-regulated translation factor that responds to fermentation-induced acidosis affecting cellular metabolism.
Externí odkaz:
https://doaj.org/article/93b48d789e3e4b9d8f527f9c594d44a2
Autor:
J. J. David Ho, Nathan C. Balukoff, Phaedra R. Theodoridis, Miling Wang, Jonathan R. Krieger, Jonathan H. Schatz, Stephen Lee
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
mRNA translation efficiency is regulated in response to stimuli. Here the authors employ mass spectrometry analysis of ribosome fractions and show that under hypoxia, oxygen-sensitive RNA binding proteins enhance the translation efficiency of glycoly
Externí odkaz:
https://doaj.org/article/754a4b16d6cf4bd486c30441585007ea
Publikováno v:
STAR Protocols. 3:101919
Here, we present a protocol using MATRIX (mass spectrometry analysis of active translation factors using ribosome density fractionation and isotopic labeling experiments) platform to investigate changes of the protein synthesis machinery in U87MG gli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10eda436621ac16a22b0eaa519b34e58
https://doi.org/10.1016/j.xpro.2022.101919
https://doi.org/10.1016/j.xpro.2022.101919
Autor:
J J David, Ho, Philip A, Marsden
Publikováno v:
Wiley interdisciplinary reviews. RNA. 5(1)
Posttranscriptional regulation of mRNA species represents a major regulatory checkpoint in the control of gene expression. Historically, RNA-binding proteins (RBPs) have been regarded as the primary regulators of mRNA stability and translation. More
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::739aee4afcf338265d3f9489dea04165
https://pubmed.ncbi.nlm.nih.gov/24124109
https://pubmed.ncbi.nlm.nih.gov/24124109
Autor:
Jason E. Fish, Matthew S. Yan, Charles C. Matouk, Rosanne St. Bernard, J. J. David Ho, Anna Gavryushova, Deepak Srivastava, Philip A. Marsden
Publikováno v:
Journal of Biological Chemistry. 285:11754
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d70bccce0e7983f91f78b1fda69a195
https://doi.org/10.1074/jbc.a109.067868
https://doi.org/10.1074/jbc.a109.067868