Zobrazeno 1 - 10
of 128
pro vyhledávání: '"J. J. Broerse"'
Publikováno v:
European Radiology Supplements. 14:19-27
For risk estimations, scientists have at their disposition results from molecular, cellular and animal experiments, risk modelling and human epidemiological studies. Much has been achieved, but large uncertainties in quantitative risk estimates of ex
Publikováno v:
Toxicologic Pathology. 31:209-213
In the early sixties, studies have been performed at the TNO-Institutes for Health Research on acute effects of high dose total body irradiation (TBI) with X-rays and fission neutrons in Rhesus monkeys and the protective effect of autologous bone mar
Autor:
J. J. Broerse, Carel F. Hollander, Matthew J. van Zwieten, Chris Zurcher, Rolf W. Bartstra, Dirk W. van Bekkum, Marein H. van der Hage
Publikováno v:
Radiotherapy and Oncology. 54:247-253
Purpose : High dose total body irradiation (TBI) in combination with chemotherapy, followed by rescue with bone marrow transplantation (BMT), is increasingly used for the treatment of haematological malignancies. With the increasing success of this t
Autor:
J. A. K. Blokland, Michel H. Bourguignon, M. E. Schmidt, T. A. F. El-Maghraby, W. H. Thomson, J. J. Broerse, L. K. Harding, Ernest K. J. Pauwels
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 26:1453-1457
Detrimental effects on the thyroid of the developing fetus as a result of iodine-131 treatment for thyrotoxicosis of the mother in the first trimester of pregnancy are discussed. Dose estimations under typical clinical circumstances yield a fetal thy
Autor:
Marein H. van der Hage, Jan M. Wit, Boudewijn Bakker, Hetty J. van der Kamp, Monique M.B Niemer-Tucker, Amir Mearadji, Ariadne M van Rijn, J. J. Broerse, Guy G. Massa
Publikováno v:
Radiotherapy and Oncology. 51:187-192
Purpose : To investigate the effect of total-body irradiation (TBI) on growth, thyroid and pituitary gland in primates. Methods and materials : Thirty-seven rhesus monkeys (mean age 3.1±0.6 years) received either a low-dose (4–6 Gy) TBI ( n =26) o
Autor:
J. J. Broerse, V. Esposito, G. Wagemaker, Christine Linard, K. J. Neelis, Agnès François, Isabelle Dublineau, M. M. B. Niemer-Tucker, N. M. Griffiths, M. H. van der Hage
Publikováno v:
International Journal of Radiation Biology, 75(2), 183-191. Informa Healthcare
To investigate the long-term effects of X-irradiation on different aspects of gastrointestinal function in the non-human primate (Macaca mulatta).Animals were exposed to X-radiation (5 or 6 Gy) or not (sham) and gastrointestinal function was investig
Autor:
L. K. Harding, Ernest K. J. Pauwels, P. Steenvoorde, B. Mariere, Michel H. Bourguignon, J. J. Broerse
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 25:193-199
The possible detrimental effects on the developing embryo subsequent to irradiation are discussed. The doses to the embryo or fetus encountered for the most common procedures in diagnostic nuclear medicine are evaluated with respect to the threshold
Publikováno v:
Radiotherapy and Oncology, 51, pp. 1-9
Radiotherapy and Oncology, 51, 1-9
Radiotherapy and Oncology, 51, 1-9
Purpose : In order to determine the presence of cardiac damage associated with total-body irradiation (TBI), both echocardiographic parameters and circulating levels of atrial natriuretic peptide (ANP) were measured in three different age-cohorts of
Autor:
J. J. Broerse, J. Zoetelief, J. T. M. Jansen, W. P. Hiestand, F. A. I. Busscher, H. W. Julius
Publikováno v:
International Journal of Radiation Biology. 72:627-632
Purpose: To foster quality assurance of dosimetry among the institutes involved in joint studies on late effects of ionizing radiation. Materials and methods: The participants in the dosimetry intercomparison received for each facility two mouse phan
Long-term Consequences of High-dose Total-body Irradiation on Hepatic and Renal Function in Primates
Autor:
J. J. Broerse, B. Bakker, M.M.J.H. Sluysmans, Chris Zurcher, M. M. B. Niemer-Tucker, J. Davelaar
Publikováno v:
International Journal of Radiation Biology. 68:83-96
Radiation effects in non-human primates were studied in order to define the long-term risk of total-body irradiation (TBI) for bone marrow transplantation patients. The long-term effects of TBI could be investigated by keeping 84 monkeys of different