Zobrazeno 1 - 10
of 18
pro vyhledávání: '"J. J. Billadello"'
Publikováno v:
Journal of Clinical Investigation. 99:67-76
The manner in which growth factors acting at the cell surface regulate activity of myogenic basic-helix-loop-helix proteins in the nucleus and thus control the fate of committed skeletal myoblasts remains poorly understood. In this study, we report t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b0770282659cf46c803f656280525e9
https://doi.org/10.1172/jci119135
https://doi.org/10.1172/jci119135
Publikováno v:
The Journal of biological chemistry. 269(34)
Multiple transforming growth factor-beta (TGF-beta) responsive elements have been identified within the 5'-flanking region of the plasminogen activator inhibitor type-1 (PAI-1) gene. This study was designed to characterize the major TGF-beta responsi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c0ec0c8aa45e51cd0872ec97fd2b9016
https://pubmed.ncbi.nlm.nih.gov/8063785
https://pubmed.ncbi.nlm.nih.gov/8063785
Autor:
K J, Hawker, J J, Billadello
Publikováno v:
BioTechniques. 14(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47017cdd717f2060d7a52f0f1c0ad101
https://pubmed.ncbi.nlm.nih.gov/8512699
https://pubmed.ncbi.nlm.nih.gov/8512699
Publikováno v:
The Journal of biological chemistry. 267(18)
In humans and non-human primates, alternative cleavage and polyadenylation of plasminogen activator inhibitor type-1 (PAI-1) pre-mRNA transcripts results in two forms of mature mRNA, an unstable 3.2-kilobase (kb) form, and a relatively more stable 2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3478269a2769cc5d1a772f8cbaecc7c6
https://pubmed.ncbi.nlm.nih.gov/1618746
https://pubmed.ncbi.nlm.nih.gov/1618746
Publikováno v:
The Journal of biological chemistry. 266(27)
Creatine kinase (EC 2.7.3.2) (CK) isoenzymes are crucial to energy metabolism, particularly in tissues with high energy requirements. Nuclear genes encode four known CK subunits: cytoplasmic muscle, cytoplasmic brain, ubiquitous mitochondrial (uMtCK)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f04a030df1531f446fc749bad3c744f
https://pubmed.ncbi.nlm.nih.gov/1917943
https://pubmed.ncbi.nlm.nih.gov/1917943
Publikováno v:
Thrombosis and haemostasis. 66(2)
Plasminogen activator inhibitor type-1 (PAI-1) is a physiologic modulator of the fibrinolytic system. We have shown previously that PAI-1 biosynthesis in cultured cells depends on several factors in serum. Because platelets are richly endowed with sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4b90daa835b0e968667d6d941fd09932
https://pubmed.ncbi.nlm.nih.gov/1663280
https://pubmed.ncbi.nlm.nih.gov/1663280
Publikováno v:
The Journal of biological chemistry. 266(2)
Regulation of plasminogen activation by plasminogen activator inhibitor type-1 (PAI-1) is a critical feature of many biological processes. Transforming growth factor-beta (TGF-beta) induces PAI-1 mRNA and protein in several types of cultured cells, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::92d2579d6fda1aab9241f98347584387
https://pubmed.ncbi.nlm.nih.gov/1985937
https://pubmed.ncbi.nlm.nih.gov/1985937
Publikováno v:
Thrombosis and haemostasis. 64(3)
Plasminogen activator inhibitor type-1 (PAI-1) can modify fibrinolytic activity in vitro and in vivo. The present study was performed to determine whether pharmacologic concentrations of tissue-type plasminogen activator (t-PA) can initiate negative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8edb901f3843d29c0f07377548b20cbb
https://pubmed.ncbi.nlm.nih.gov/2128971
https://pubmed.ncbi.nlm.nih.gov/2128971
Publikováno v:
The Journal of biological chemistry. 265(24)
Complexes between tissue-type plasminogen activator (t-PA) and its rapidly acting inhibitor plasminogen activator inhibitor type 1 (PAI-1) are bound, internalized, and degraded by HepG2 cells. The mechanism involves endocytosis mediated by a specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a96f1450a0b655b853db89618d55efd6
https://pubmed.ncbi.nlm.nih.gov/2167306
https://pubmed.ncbi.nlm.nih.gov/2167306
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 31(2)
Prompt detection of acute thrombosis and its response to treatment with thrombolytic agents generally require angiography. Scintigraphic approaches with labeled antibodies to or components of the coagulation and fibrinolytic systems have been disappo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::534677660f360bb3c57993110e473bf3
https://pubmed.ncbi.nlm.nih.gov/2107282
https://pubmed.ncbi.nlm.nih.gov/2107282