Zobrazeno 1 - 10
of 14
pro vyhledávání: '"J. J. Bieker"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract The onset of erythropoiesis is under strict developmental control, with direct and indirect inputs influencing its derivation from the hematopoietic stem cell. A major regulator of this transition is KLF1/EKLF, a zinc finger transcription fa
Externí odkaz:
https://doaj.org/article/006e26cb02ef477a9db79a4616754419
Publikováno v:
Journal of Biological Chemistry. 269:15440-15444
Erythroid Kruppel-like factor (EKLF) is an erythroid-specific transcription factor that binds a CACCC motif found in the human beta-globin gene promoter. We have studied the promoter of the EKLF gene and identified binding sites for the transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd2bf728a91f8f8150f9a94f1833bd69
https://doi.org/10.1016/s0021-9258(17)40698-3
https://doi.org/10.1016/s0021-9258(17)40698-3
Publikováno v:
The Journal of Cell Biology
The pattern of type II collagen expression during Xenopus laevis embryogenesis has been established after isolating specific cDNA and genomic clones. Evidence is presented suggesting that in X. laevis there are two transcriptionally active copies of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6af1fad0d76e4b559b0f4a5d3139aaf
https://doi.org/10.1083/jcb.115.2.565
https://doi.org/10.1083/jcb.115.2.565
Publikováno v:
Blood. 90(3)
Using homologous recombination, both EKLF alleles in murine embryonic stem (ES) cells were inactivated. These EKLF-/- ES cells were capable of undergoing in vitro differentiation to form definitive erythroid colonies that were similar in size and num
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d56d5252648485e682cfc05290711a9
https://pubmed.ncbi.nlm.nih.gov/9242564
https://pubmed.ncbi.nlm.nih.gov/9242564
Autor:
X. Chen, J. J. Bieker
Erythroid Kruppel-like factor (EKLF) is a red cell-restricted transcriptional activator that plays a dominant role in establishing high levels of beta-globin gene expression during erythroid ontogeny. Although its DNA binding domain belongs to the we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6cd35be9b687d8d4790473c0760495
https://europepmc.org/articles/PMC452347/
https://europepmc.org/articles/PMC452347/
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 206(3)
Erythroid Krüppel-like factor (EKLF) is an erythroid cell-specific transcription factor that mediates activation via binding to a 9 base pair sequence that encompasses the CACCC element, one of a trio of evolutionarily conserved sequence motifs that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::14d18ba79a0b27f7dc5e636604121684
https://pubmed.ncbi.nlm.nih.gov/8896981
https://pubmed.ncbi.nlm.nih.gov/8896981
Publikováno v:
The Journal of biological chemistry. 269(22)
Erythroid Kruppel-like factor (EKLF) is an erythroid-specific transcription factor that binds a CACCC motif found in the human beta-globin gene promoter. We have studied the promoter of the EKLF gene and identified binding sites for the transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::62cb5b536aeb2e97d8733674bdf14427
https://pubmed.ncbi.nlm.nih.gov/8195185
https://pubmed.ncbi.nlm.nih.gov/8195185
Publikováno v:
The Journal of biological chemistry. 269(2)
We describe functional tests and molecular modeling of erythroid Krüppel-like factor (EKLF) interactions with its DNA binding site. EKLF, a zinc finger-containing, erythroid-specific transcription factor, binds and transactivates from the CACCC elem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c07274989ca3fe2a850aaba597aaced
https://pubmed.ncbi.nlm.nih.gov/8288615
https://pubmed.ncbi.nlm.nih.gov/8288615
Autor:
J J Bieker, R G Roeder
Publikováno v:
Journal of Biological Chemistry. 259:6158-6164
A factor ( TFIIIA ) specifically required for transcription of the 5 S RNA gene has been physically and enzymatically characterized in its native state. TFIIIA is a monomer of 38,600 Da with a Stokes radius of 34 A and a sedimentation coefficient of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91cb2788c758cd4dd3dc8225e84af713
https://doi.org/10.1016/s0021-9258(20)82119-x
https://doi.org/10.1016/s0021-9258(20)82119-x
Autor:
J J Bieker, R G Roeder
Publikováno v:
Journal of Biological Chemistry. 261:9732-9738
We previously demonstrated that the rate-limiting step in 5 S RNA transcription involves the ordered assembly of a preinitiation complex on the 5 S gene that requires magnesium and ATP for its formation and contains stoichiometric amounts of transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a2ffaaaaef3a2aa61319be578f96b38
https://doi.org/10.1016/s0021-9258(18)67576-3
https://doi.org/10.1016/s0021-9258(18)67576-3