Zobrazeno 1 - 10
of 15
pro vyhledávání: '"J. Izaak Miller"'
Autor:
Kyle A. Sullivan, Matthew Lane, Mikaela Cashman, J. Izaak Miller, Mirko Pavicic, Angelica M. Walker, Ashley Cliff, Jonathon Romero, Xuejun Qin, Niamh Mullins, Anna Docherty, Hilary Coon, Douglas M. Ruderfer, International Suicide Genetics Consortium, VA Million Veteran Program, MVP Suicide Exemplar Workgroup, Michael R. Garvin, John P. Pestian, Allison E. Ashley-Koch, Jean C. Beckham, Benjamin McMahon, David W. Oslin, Nathan A. Kimbrel, Daniel A. Jacobson, David Kainer
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract Genome-wide association studies (GWAS) identify genetic variants underlying complex traits but are limited by stringent genome-wide significance thresholds. We present GRIN (Gene set Refinement through Interacting Networks), which increases
Externí odkaz:
https://doaj.org/article/f343f4bdee8040aa88cb30c2c4276f5a
Autor:
Alan E Mast, Alisa S Wolberg, David Gailani, Michael R Garvin, Christiane Alvarez, J Izaak Miller, Piet Jones, Bruce Aronow, Daniel Jacobson
Publikováno v:
eLife, Vol 11 (2022)
Early in the SARS-CoV-2 pandemic, we compared transcriptome data from hospitalized COVID-19 patients and control patients without COVID-19. We found changes in procoagulant and fibrinolytic gene expression in the lungs of COVID-19 patients (Mast et a
Externí odkaz:
https://doaj.org/article/6f80d1bcca304f5ab500cec044ad3eb3
Autor:
Alan E Mast, Alisa S Wolberg, David Gailani, Michael R Garvin, Christiane Alvarez, J Izaak Miller, Bruce Aronow, Daniel Jacobson
Publikováno v:
eLife, Vol 10 (2021)
Extensive fibrin deposition in the lungs and altered levels of circulating blood coagulation proteins in COVID-19 patients imply local derangement of pathways that limit fibrin formation and/or promote its clearance. We examined transcriptional profi
Externí odkaz:
https://doaj.org/article/c9cf14268af2449ebec4df152af85aff
Autor:
Michael G. Levin, Jennifer E. Huffman, Anurag Verma, Kyle A. Sullivan, Alexis A. Rodriguez, David Kainer, Michael R. Garvin, Matthew Lane, Mikaela Cashman, J. Izaak Miller, Hyejung Won, Binglan Li, Yuan Luo, Gail P. Jarvik, Hakon Hakonarson, Elizabeth A. Jasper, Alexander G. Bick, Philip S. Tsao, Marylyn D. Ritchie, Daniel A. Jacobson, Ravi K. Madduri, Scott M. Damrauer
Publikováno v:
Nature Cardiovascular Research. 2:44-57
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f0e738aa4f16b046846e4638ebd46f5
https://doi.org/10.1038/s44161-022-00196-5
https://doi.org/10.1038/s44161-022-00196-5
Autor:
Michael R Garvin, Christiane Alvarez, J Izaak Miller, Erica T Prates, Angelica M Walker, B Kirtley Amos, Alan E Mast, Amy Justice, Bruce Aronow, Daniel Jacobson
Publikováno v:
eLife, Vol 9 (2020)
Neither the disease mechanism nor treatments for COVID-19 are currently known. Here, we present a novel molecular mechanism for COVID-19 that provides therapeutic intervention points that can be addressed with existing FDA-approved pharmaceuticals. T
Externí odkaz:
https://doaj.org/article/7ca8502352754188ae4bff950a8b4f2e
Autor:
Erica T. Prates, Michael R. Garvin, Piet Jones, J. Izaak Miller, Kyle A. Sullivan, Ashley Cliff, Joao Gabriel Felipe Machado Gazolla, Manesh B. Shah, Angelica M. Walker, Matthew Lane, Christopher T. Rentsch, Amy Justice, Mirko Pavicic, Jonathon Romero, Daniel Jacobson
Publikováno v:
Methods in Molecular Biology ISBN: 9781071621103
The unprecedented scientific achievements in combating the COVID-19 pandemic reflect a global response informed by unprecedented access to data. We now have the ability to rapidly generate a diversity of information on an emerging pathogen and, by us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c33a8af68cfbbc8e1c8bc2c209bb0ad
https://researchonline.lshtm.ac.uk/id/eprint/4665613/1/Prates_etal_2022_Antiviral-Strategies-Against-SARS-CoV-2.pdf
https://researchonline.lshtm.ac.uk/id/eprint/4665613/1/Prates_etal_2022_Antiviral-Strategies-Against-SARS-CoV-2.pdf
Autor:
Erica T, Prates, Michael R, Garvin, Piet, Jones, J Izaak, Miller, Kyle A, Sullivan, Ashley, Cliff, Joao Gabriel Felipe Machado, Gazolla, Manesh B, Shah, Angelica M, Walker, Matthew, Lane, Christopher T, Rentsch, Amy, Justice, Mirko, Pavicic, Jonathon, Romero, Daniel, Jacobson
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2452
The unprecedented scientific achievements in combating the COVID-19 pandemic reflect a global response informed by unprecedented access to data. We now have the ability to rapidly generate a diversity of information on an emerging pathogen and, by us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3dd6f9a9e4a4937473948893da6aba75
https://pubmed.ncbi.nlm.nih.gov/35554915
https://pubmed.ncbi.nlm.nih.gov/35554915
Autor:
David Gailani, Alisa S Wolberg, Alan E Mast, Michael R Garvin, Christiane Alvarez, J Izaak Miller, Piet Jones, Bruce Aronow, Daniel Jacobson
Publikováno v:
eLife, Vol 11 (2022)
Early in the SARS-CoV-2 pandemic, we compared transcriptome data from hospitalized COVID-19 patients and control patients without COVID-19. We found changes in procoagulant and fibrinolytic gene expression in the lungs of COVID-19 patients (Mast et a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ff63b3772e219af23ba39f6caada12
https://elifesciences.org/articles/74951
https://elifesciences.org/articles/74951
Autor:
Alisa S. Wolberg, Bruce Aronow, Alan E. Mast, Christiane Alvarez, Daniel Jacobson, Michael R. Garvin, David Gailani, J Izaak Miller
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Extensive fibrin deposition in the lungs and altered levels of circulating blood coagulation proteins in COVID-19 patients imply local derangement of pathways that limit fibrin formation and/or promote its clearance. We examined transcriptional profi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6ae179882e9a746ee1371c47a34b2a
https://doi.org/10.7554/elife.64330
https://doi.org/10.7554/elife.64330
Autor:
Angelica M. Walker, Michael R. Garvin, B Kirtley Amos, Christiane Alvarez, Bruce J. Aronow, J Izaak Miller, Alan E. Mast, Amy C. Justice, Daniel Jacobson, Erica T. Prates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a02bf0d0f81301a87f2a636b3f53c284
https://doi.org/10.7554/elife.59177.sa2
https://doi.org/10.7554/elife.59177.sa2