Zobrazeno 1 - 6
of 6
pro vyhledávání: '"J. Iker Etchegaray"'
Autor:
J. Iker Etchegaray, Shannon Kelley, Kristen Penberthy, Laura Karvelyte, Yosuke Nagasaka, Sofia Gasperino, Soumen Paul, Vikram Seshadri, Michael Raymond, Ana Royo Marco, Jonathan Pinney, Marta Stremska, Brady Barron, Christopher Lucas, Nishikant Wase, Yong Fan, Emil Unanue, Bijoy Kundu, Tal Burstyn-Cohen, Justin Perry, Jayakrishna Ambati, Kodi S. Ravichandran
Publikováno v:
Etchegaray, J I, Kelley, S, Penberthy, K K, Karvelyte, L, Nagasaka, Y, Gasperino, S, Paul, S, Seshadri, V, Raymond, M H, Marco, A R, Pinney, J, Stremska, M E, Barron, B, Lucas, C D, Wase, N, Fan, Y, Unanue, E, Kundu, B, Burstyn-Cohen, T, Perry, J S A, Jayakrishna, A & Ravichandran, K S 2023, ' Phagocytosis in the retina promotes local insulin production in the eye ', Nature Metabolism . https://doi.org/10.1038/s42255-022-00728-0
The retina is highly metabolically active, relying on glucose uptake and aerobic glycolysis. Situated in close contact to photoreceptors, a key function of cells in the retinal pigment epithelium (RPE) is phagocytosis of damaged photoreceptor outer s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e015ab2ee76d21aacd3289ac8c786341
https://doi.org/10.1038/s42255-022-00728-0
https://doi.org/10.1038/s42255-022-00728-0
Autor:
Christopher D. Lucas, Christopher B. Medina, Finnius A. Bruton, David A. Dorward, Michael H. Raymond, Turan Tufan, J. Iker Etchegaray, Brady Barron, Magdalena E. M. Oremek, Sanja Arandjelovic, Emily Farber, Suna Onngut-Gumuscu, Eugene Ke, Moira K. B. Whyte, Adriano G. Rossi, Kodi S. Ravichandran
Publikováno v:
SCIENCE IMMUNOLOGY
Lucas, C D, Medina, C B, Bruton, F, Dorward, D, Raymond, M H, Tufan, T, Etchegaray, J I, Barron, B, Oremek, M, Arandjelovic, S, Farber, E, Onngut-Gumuscu, S, Ke, E, Whyte, M K B, Rossi, A G & Ravichandran, K S 2022, ' Pannexin 1 drives efficient epithelial repair after tissue injury ', Science Immunology, vol. 7, no. 71, eabm4032 . https://doi.org/10.1126/sciimmunol.abm4032
Lucas, C D, Medina, C B, Bruton, F, Dorward, D, Raymond, M H, Tufan, T, Etchegaray, J I, Barron, B, Oremek, M, Arandjelovic, S, Farber, E, Onngut-Gumuscu, S, Ke, E, Whyte, M K B, Rossi, A G & Ravichandran, K S 2022, ' Pannexin 1 drives efficient epithelial repair after tissue injury ', Science Immunology, vol. 7, no. 71, eabm4032 . https://doi.org/10.1126/sciimmunol.abm4032
Epithelial tissues such as lung and skin are exposed to the environment and therefore particularly vulnerable to damage during injury or infection. Rapid repair is therefore essential to restore function and organ homeostasis. Dysregulated epithelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63b391a65e38300beccab46d3723b79a
https://pubmed.ncbi.nlm.nih.gov/35559667
https://pubmed.ncbi.nlm.nih.gov/35559667
Autor:
Kodi S. Ravichandran, Christopher B. Medina, Brady J. Barron, Suna Onengut-Gumuscu, Eric Delpire, Sho Morioka, J. Iker Etchegaray, Christopher D. Lucas, Justin S. A. Perry, Michael H. Raymond
Publikováno v:
Nature cell biology
Perry, J S A, Morioka, S, Medina, C B, Etchegaray, J I, Barron, B, Raymond, M H, Lucas, C D, Onengut-Gumuscu, S, Delpire, E & Ravichandran, K S 2019, ' Interpreting an apoptotic corpse as anti-inflammatory involves a chloride sensing pathway ', Nature Cell Biology, vol. 21, no. 12, pp. 1532–1543 . https://doi.org/10.1038/s41556-019-0431-1
Perry, J S A, Morioka, S, Medina, C B, Etchegaray, J I, Barron, B, Raymond, M H, Lucas, C D, Onengut-Gumuscu, S, Delpire, E & Ravichandran, K S 2019, ' Interpreting an apoptotic corpse as anti-inflammatory involves a chloride sensing pathway ', Nature Cell Biology, vol. 21, no. 12, pp. 1532–1543 . https://doi.org/10.1038/s41556-019-0431-1
Apoptotic cell clearance (efferocytosis) elicits an anti-inflammatory response by phagocytes, but the mechanisms that underlie this response are still being defined. Here, we uncover a chloride-sensing signalling pathway that controls both the phagoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50a73624ad94f19652153a4515cf2450
http://europepmc.org/articles/PMC7140761
http://europepmc.org/articles/PMC7140761
Autor:
J. Iker Etchegaray, David Le, Li Xuan Tan, Li Gan, Yaqiao Li, Nicholas T. Seyfried, Faten A. Sayed, Thomas G. Kukar, Claire D. Clelland, Lihong Zhan, Aparna Lakkaraju, Yungui Zhou, Bruce Conklin, Duc M. Duong, Aradhana Sachdev, Lay Kodama
Publikováno v:
Alzheimer's & Dementia. 15:P1509-P1509
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a13ff1e06465f84c6d2015537f0b9db7
https://doi.org/10.1016/j.jalz.2019.08.057
https://doi.org/10.1016/j.jalz.2019.08.057
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