Zobrazeno 1 - 10
of 155
pro vyhledávání: '"J. IGOLEN"'
Autor:
Jean-Yves Lallemand, Veronique Stoven, Tam Huynh-Dinh, Jean-Claude Chottard, Eric Guittet, Frédéric Herman, Jiřarí Kozelka, Jean-Pierre Girault, J. Igolen
Publikováno v:
European Journal of Biochemistry
European Journal of Biochemistry, 1990, 194 (1), pp.119-133. ⟨10.1111/j.1432-1033.1990.tb19435.x⟩
European Journal of Biochemistry, 1990, 194 (1), pp.119-133. ⟨10.1111/j.1432-1033.1990.tb19435.x⟩
A conformational study of the double-stranded decanucleotide d(GCCG*G*ATCGC).d(GCGATCCGGC), with the G* guanines chelating a cis-Pt(NH3)2 moiety, has been accomplished using 1H and 31P NMR, and molecular mechanics. Correlation of the NMR data with mo
Publikováno v:
ChemInform. 21
Publikováno v:
Journal of Heterocyclic Chemistry. 20:1169-1173
Synthese d'analogues acycliques de nucleosides ou la chaine est liee a la base heterocyclique par une liaison carbone-carbone. Nous decrivons une methode directe pour la preparation de derives de la guanine et de la s-triazolo[1,5-a]pyridine. A direc
Publikováno v:
Chemistry and Physics of Lipids. 33:41-45
Analytically pure 1,2-dipalmitoyl-sn-glycero-3-phosphoric acid was prepared in gram amounts, using a simplified version of a previous procedure. The main step, enzymatic cleavage of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine with freshly extracted p
Publikováno v:
Biochimie. 71(3)
A simple chemical method for the synthesis of non-radioactive DNA probes is described: triazolyl-containing sequences were built by incorporation of 4-triazolylpyrimidin-2-ones instead of cytidines during oligodeoxyribonucleotide synthesis. The activ
Publikováno v:
European journal of biochemistry. 161(3)
Exhaustive conformational studies of d(CpG)2 and d(m5CpG)2, two convenient targets for DNA bisintercalating drugs, have been carried out by 1H and 31P NMR in low salt concentration and in the presence of 30% ethanol. Unambiguous 31P assignments of th
Publikováno v:
Chemischer Informationsdienst. 12
Publikováno v:
European journal of biochemistry. 121(2)
Autor:
J. B. Le Pecq, Muriel Delepierre, Bernard-Pierre Roques, J. Igolen, A. Delbarre, Christiane Garbay
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 84(8)
Rigid 7H-pyrido[4,3-c]carbazole dimers, such as Ditercalinium, are DNA bisintercalators that display high DNA affinity and strong antitumor properties. This activity appears crucially dependent on the geometry of their complexes with DNA. Therefore,
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 82(22)
Two simple alternatives to the synthesis of mixed oligodeoxyribonucleotide probes are described: mixed deblocking of triazolodeoxynucleosides for the A/G and C/T degeneracies or incorporation of 2-amino-2'-deoxyadenosines into a determined sequence f