Výsledky vyhledávání - "J. I. Schwartz"

Metabolic profiles of montelukast sodium (Singulair), a potent cysteinyl leukotriene1 receptor antagonist, in human plasma and bile

Autor: S K, Balani, X, Xu, V, Pratha, M A, Koss, R D, Amin, C, Dufresne, R R, Miller, B H, Arison, G A, Doss, M, Chiba, A, Freeman, S D, Holland, J I, Schwartz, K C, Lasseter, B J, Gertz, J I, Isenberg, J D, Rogers, J H, Lin, T A, Baillie

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 25(11)

Montelukast sodium [1-([(1(R)-(3-(2-(7-chloro-2-quinolinyl)-(E)- ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio]methyl)cyclopropylacetic acid sodium salt] (MK-476, Singulair) is a potent and selective antagonist of the cysteinyl leu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::140bb2404e1a6c363c31a26c7f86ba21
https://pubmed.ncbi.nlm.nih.gov/9351905

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Evaluation of sustained/controlled-release dosage forms of 3-hydroxy-3-methylglutaryl-coenzyme a (HMG-CoA) reductase inhibitors in dogs and humans

Autor: H, Cheng, S C, Sutton, J D, Pipkin, G M, Zentner, J D, Rogers, J I, Schwartz, Y B, Mitchel, K, Grasing, M S, Schwartz, R D, Amin

Publikováno v: Pharmaceutical research. 10(11)

Seven sustained/controlled-release dosage forms were designed for gastrointestinal delivery of lovastatin or simvastatin, two potent HMG-CoA reductase inhibitors for the treatment of hypercholesterolemia. The in vivo performance of these formulations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e2435701621d31d1a89846d4cd118cf5
https://pubmed.ncbi.nlm.nih.gov/8290485

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Friction-Induced Heating in Axially Loaded Ball Bearings

Autor: J. I. Schwartz

Publikováno v: Journal of Lubrication Technology. 92:105-111

This paper compares theoretical and experimental results on the friction-induced heating in thrust-loaded ball bearings at constant speed. Heat transfer and friction heat-generation models are developed for the bearings using computer techniques. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::883e877be921b3d981f865581a5358eb
https://doi.org/10.1115/1.3451280

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The suitability of carbamazepine as a single-sample probe of human mixed function oxidase activity

Autor: L. Jauregui, J. I. Schwartz, Kenneth Bachmann

Publikováno v: Xenobiotica; the fate of foreign compounds in biological systems. 19(7)

1. Carbamazepine concentrations measured in plasma and plasma ultrafiltrates by fluorescence polarization immunoassay (f.p.i.a.) from 0 to 48 h post-dose were used to calculate CL, V, clearance of plasma unbound drug (CLunb), Vunb; mean (+/- SD) valu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e174403ea5d3305981bad588285a80
https://pubmed.ncbi.nlm.nih.gov/2773507

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Computer-assisted practitioner-response system for studying the use of cimetidine

Autor: J I, Schwartz, T J, Kennedy

Publikováno v: American journal of hospital pharmacy. 39(7)

A computer-assisted practitioner-response system was used to review cimetidine use in one hospital. All patients receiving cimetidine from April 1, 1981, through May 15, 1981, were identified daily using a computerized medication-profile system. A pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::363a088e07291c5f0e7d32e6059b4c6b
https://pubmed.ncbi.nlm.nih.gov/7114066

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Use of a tabletop computer in controlled substances distribution

Autor: R E, Markin, J I, Schwartz, A E, Sell

Publikováno v: American journal of hospital pharmacy. 39(7)

The use of a tabletop computer for controlled substances distribution is described. The self-contained system uses programs stored on discs to maintain records for floor stock, individual patient orders, and ambulatory patient prescriptions. Three re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f3a0c890f8f556ff297fd1f215003bd7
https://pubmed.ncbi.nlm.nih.gov/7114065

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