Zobrazeno 1 - 10
of 48
pro vyhledávání: '"J. I. Javaid"'
Publikováno v:
Neuropharmacology. 39:88-98
We investigated the physiological role of native low- and high-affinity nicotinic acetylcholine receptors (nAChRs) in regulating dopamine (DA) release from striatal DA terminals. To evaluate the functional interactions of the two receptor subtypes, n
Autor:
J. I. Javaid
Publikováno v:
The Journal of Clinical Pharmacology. 34:286-295
The antipsychotics are a chemically diverse group of heterocyclic compounds, which ameliorate many symptoms of schizophrenia. Most of the antipsychotics are very lipophilic and cross lipoidal membranes freely. When administered orally, they are well
Autor:
J. I. Javaid, John M. Davis
Publikováno v:
Biopharmaceutics & Drug Disposition. 14:357-364
It has been proposed that various effects of psychoactive drugs on the central nervous system may be related to the capacity of the drug to selectively concentrate in specific regions of the brain. In rat brain, cocaine effects on striatal and nucleu
Autor:
Robert B. Parker, Karen J. Beckman, Jerry L. Bauman, J. I. Javaid, Jose Gallastegui, R. J. Hariman
Publikováno v:
Circulation. 83:1799-1807
BACKGROUND Cocaine abuse has been implicated as a cause of death due to sudden cardiac arrest. METHODS AND RESULTS We examined the hemodynamic and electrophysiological effects of cocaine administered as a series of 5-mg/kg i.v. boluses coupled with a
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 287(1)
Imidazenil, a benzodiazepine recognition site ligand that acts as partial positive allosteric modulator of gamma-aminobutyric acid (GABA) action at GABAA receptors, inhibits in a dose-dependent manner (0.56-2.5 micromol/kg i.p. to rats) the cocaine-i
Publikováno v:
Past, Present and Future of Psychiatry.
Publikováno v:
Psychiatric medicine. 9(1)
This chapter begins with an introduction to the usefulness of plasma levels in general, addressing their utility in monitoring compliance and toxicity. Particular classes of psychotropic medications and the specific medications within them are addres
Publikováno v:
Psychosomatic medicine. 52(6)
Although agonist-induced desensitization of adrenergic receptors has been previously demonstrated, the regulation of adrenergic receptors during acute psychological stress has not been investigated in humans. We studied 30 first year medical students
Publikováno v:
Acta psychiatrica Scandinavica. 82(1)
Phenylacetic acid (PAA) excretion was measured in 39 patients who met criteria for panic disorder; 9 of these also had major depression, and 30 did not. Patients with panic and depression excreted 66 +/- 23 mg/day of PAA, an amount significantly lowe
Publikováno v:
Psychopharmacology bulletin. 26(3)
Plasma homovanillic acid (pHVA) was measured in 40 inpatients (25 schizophrenic and 15 nonschizophrenic patients) who underwent up to 3 weeks of drug washout. Schizophrenic patients were then treated with trifluoperazine for 4 weeks, and weekly behav