Zobrazeno 1 - 10
of 195
pro vyhledávání: '"J. I. Isenberg"'
Autor:
J. I. Isenberg
Publikováno v:
Alimentary Pharmacology & Therapeutics. 1:447s-454s
SUMMARY The epidemiology and character of peptic ulcer has changed over the last 20 years, with only some of the change being due to the introduction of H2-receptor antagonists in the mid-1970s. There is evidence that duodenal ulcer was declining bef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3fef986b489d208c5ef14994c9c7a56
https://doi.org/10.1111/j.1365-2036.1987.tb00655.x
https://doi.org/10.1111/j.1365-2036.1987.tb00655.x
Autor:
J. I. Isenberg, D. L. Hogan
Publikováno v:
Journal of Internal Medicine. 228:113-117
Over the past few years, we have addressed some of the components that regulate human duodenal bicarbonate secretion (DBS) using a technique for the isolation of a 4-cm duodenal segment from gastric, pancreaticobiliary and distal intestinal secretion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf5eb3c19714c03995d68627dc64037
https://doi.org/10.1111/j.1365-2796.1990.tb01482.x
https://doi.org/10.1111/j.1365-2796.1990.tb01482.x
Autor:
C R, Boland, J I, Isenberg
Publikováno v:
Gastroenterology. 120(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9baf581f851bd0fef4fe5890a413cddc
https://pubmed.ncbi.nlm.nih.gov/11313322
https://pubmed.ncbi.nlm.nih.gov/11313322
Publikováno v:
Digestive diseases and sciences. 43(6)
The proximal duodenal epithelium secretes bicarbonate into an adherent mucus layer, thereby protecting the mucosa from injury by gastric acid and pepsin. While bicarbonate secretion is stimulated and inhibited by a number of agonists and antagonists,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6dc5683f011c45b767cd3a47eceffca7
https://pubmed.ncbi.nlm.nih.gov/9635609
https://pubmed.ncbi.nlm.nih.gov/9635609
Publikováno v:
Digestive diseases and sciences. 43(1)
Surface epithelial bicarbonate secretion protects the proximal duodenum from acid peptic injury. Cyclic adenosine monophosphate and calcium serve as intracellular mediators of intestinal transport. Experiments were performed to examine whether calciu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::191c4a43da64628457e1f40a2d352dcf
https://pubmed.ncbi.nlm.nih.gov/9508512
https://pubmed.ncbi.nlm.nih.gov/9508512
Autor:
S K, Balani, X, Xu, V, Pratha, M A, Koss, R D, Amin, C, Dufresne, R R, Miller, B H, Arison, G A, Doss, M, Chiba, A, Freeman, S D, Holland, J I, Schwartz, K C, Lasseter, B J, Gertz, J I, Isenberg, J D, Rogers, J H, Lin, T A, Baillie
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 25(11)
Montelukast sodium [1-([(1(R)-(3-(2-(7-chloro-2-quinolinyl)-(E)- ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio]methyl)cyclopropylacetic acid sodium salt] (MK-476, Singulair) is a potent and selective antagonist of the cysteinyl leu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::140bb2404e1a6c363c31a26c7f86ba21
https://pubmed.ncbi.nlm.nih.gov/9351905
https://pubmed.ncbi.nlm.nih.gov/9351905
Publikováno v:
The American journal of physiology. 265(4 Pt 1)
The duodenum, in contrast to the jejunum, actively secretes HCO3- at a high rate, a process that protects the mucosa from acid/peptic injury. Our purpose was to define the mechanisms involved in HCO3- transport by studying the acid-base transport pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9f2d5ac7bf85d53a3565deb59e299b
https://pubmed.ncbi.nlm.nih.gov/8238351
https://pubmed.ncbi.nlm.nih.gov/8238351
Autor:
Henry O. Wheeler, F.N. Vaida, Kevin S. Haynes, J. I. Isenberg, Horacio Jinich-Brook, Susan L. Orloff, Marshall J. Orloff, R. C. Rapier, R. J. Hye
Publikováno v:
Transplantation Journal. 90:816
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bdc6f38d69f7c24f02f34efa7dd1e94
https://doi.org/10.1097/00007890-201007272-01592
https://doi.org/10.1097/00007890-201007272-01592
Publikováno v:
Gastroenterology. 102(4 Pt 1)
Gastric acid enters the proximal duodenum both as free and buffered H+. The procedures in this study were threefold: (a) to determine the pH threshold for duodenal mucosal bicarbonate secretion, iso-osmolar citric acid (pH 2.5-4.0; H+, 1.1 mmol) was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::53fb14d350b1c8b986886eafe0956d19
https://pubmed.ncbi.nlm.nih.gov/1551532
https://pubmed.ncbi.nlm.nih.gov/1551532
Publikováno v:
Gastroenterology. 98(4)
When the proximal duodenum of animals or humans is perfused with isoosmolar NaCl, bicarbonate enters the luminal effluent. In addition, duodenal bicarbonate output is stimulated by luminal acidification and prostaglandins of the E class. The hypothes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d978246f03f7ffaf031deec6aed91059
https://pubmed.ncbi.nlm.nih.gov/2311874
https://pubmed.ncbi.nlm.nih.gov/2311874