Zobrazeno 1 - 10
of 382
pro vyhledávání: '"J. Huss"'
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 7852
More than 80,000 new cases of bladder cancer are estimated to be diagnosed in 2023. However, the 5-year survival rate for bladder cancer has not changed in decades, highlighting the need for prevention. Numerous cancer-causing mutations are present i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c2f82e073c017bc75cc9eced0170b84
S1. Growth Curves and DHT metabolism in the HPr-1-AR and CWR-R1 cells. S2. ABCG2 effluxes androgens. S3. ABCG2-expressing cells enrich for stem cell markers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dbe7b5a2451770666f193242f714d53
https://doi.org/10.1158/1541-7786.22510896.v1
https://doi.org/10.1158/1541-7786.22510896.v1
Prostate stem cells (PSC) are characterized by their intrinsic resistance to androgen deprivation therapy (ADT), possibly due to the lack of androgen receptor (AR) expression. PSCs resistance to ADT and PSC expansion in castration resistant prostate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4beaea8186fed022031ec1eebb8f5745
https://doi.org/10.1158/1541-7786.c.6539763.v1
https://doi.org/10.1158/1541-7786.c.6539763.v1
Autor:
Liang, Ding, Alexandra, Gosh, Delphine J, Lee, Gabriella, Emri, Wendy J, Huss, Paul N, Bogner, Gyorgy, Paragh
Publikováno v:
Photodermatology, Photoimmunology & Photomedicine. 38:418-434
Melanomas account for only approximately 4% of diagnosed skin cancers in the United States but are responsible for the majority of deaths caused by skin cancer. Both genetic factors and ultraviolet (UV) radiation exposure play a role in the developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb1fd82e4384af3b60fb2bb31a871fa
https://doi.org/10.1111/phpp.12770
https://doi.org/10.1111/phpp.12770
Autor:
Shruti D. Shah, Bryan M. Gillard, Michelle M. Wrobel, Ellen Karasik, Michael T. Moser, Michalis Mastri, Mark D. Long, Norbert Sule, Craig M. Brackett, Wendy J. Huss, Barbara A. Foster
Publikováno v:
Frontiers in Oncology. 13
IntroductionBladder cancer is a heterogenous disease and the emerging knowledge on molecular classification of bladder tumors may impact treatment decisions based on molecular subtype. Pre-clinical models representing each subtype are needed to test
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https://explore.openaire.eu/search/publication?articleId=doi_________::2c53847908daa25a4b8e3e6a07fb6380
https://doi.org/10.3389/fonc.2023.1120329
https://doi.org/10.3389/fonc.2023.1120329
Autor:
Shruti D Shah, Bryan M Gillard, Michelle M Wrobel, Ellen Karasik, Michael T Moser, Michalis Mastri, Norbert Sule, Craig M Brackett, Wendy J Huss, Barbara A Foster
BackgroundBladder cancer is a heterogenous disease and the emerging knowledge on molecular classification of bladder tumors could have impact to drive treatment decisions based on molecular subtype. Pre-clinical models representing each subtype are n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8a504ed4d073fb5344dd75d40acf91c
https://doi.org/10.1101/2022.12.03.518865
https://doi.org/10.1101/2022.12.03.518865
Autor:
Sydney R. Grant, Spencer R. Rosario, Andrew D. Patentreger, Nico Shary, Megan E. Fitzgerald, Prashant K. Singh, Barbara A. Foster, Wendy J. Huss, Lei Wei, Gyorgy Paragh
Publikováno v:
Cancers; Volume 15; Issue 5; Pages: 1612
Mutations found in skin are acquired in specific patterns, clustering around mutation-prone genomic locations. The most mutation-prone genomic areas, mutation hotspots, first induce the growth of small cell clones in healthy skin. Mutations accumulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb25ed97304e38f6c049b850361ac17
https://doi.org/10.21203/rs.3.rs-2216887/v1
https://doi.org/10.21203/rs.3.rs-2216887/v1
Autor:
Brian J. Booth, Sami Nourreddine, Dhruva Katrekar, Yiannis Savva, Debojit Bose, Thomas J. Long, David J. Huss, Prashant Mali
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy, vol 31, iss 6
RNA therapeutics have had a tremendous impact on medicine, recently exemplified by the rapid development and deployment of mRNA vaccines to combat the COVID-19 pandemic. In addition, RNA-targeting drugs have been developed for diseases with significa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add28cc82cd74a80d722ec08d3f334e7
https://pubmed.ncbi.nlm.nih.gov/36620962
https://pubmed.ncbi.nlm.nih.gov/36620962
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Autor:
Swathi Ramakrishnan, Rick A. Kittles, Wendy J. Huss, Jianmin Wang, Kristopher Attwood, Anna Woloszynska
Publikováno v:
Metabolites
Volume 13
Issue 2
Pages: 284
Volume 13
Issue 2
Pages: 284
Dihydrotestosterone (DHT) and testosterone (T), which mediate androgen receptor nuclear translocation and target gene transcription, are crucial androgens and essential molecular triggers required for the proliferation and survival of prostate cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9f8ea485be826156fddaec53f7b641
https://doi.org/10.3390/metabo13020284
https://doi.org/10.3390/metabo13020284