Zobrazeno 1 - 10
of 298
pro vyhledávání: '"J. Hund"'
Autor:
Aaron D. Argall, Holly C. Sucharski-Argall, Luke G. Comisford, Sallie J. Jurs, Jack T. Seminetta, Michael J. Wallace, Casey A. Crawford, Sarah S. Takenaka, Mei Han, Mona El Refaey, Thomas J. Hund, Peter J. Mohler, Sara N. Koenig
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8403 (2024)
Altered ankyrin-R (AnkR; encoded by ANK1) expression is associated with diastolic function, left ventricular remodeling, and heart failure with preserved ejection fraction (HFpEF). First identified in erythrocytes, the role of AnkR in other tissues,
Externí odkaz:
https://doaj.org/article/788ff8b6db97434b9710c167319a61c4
Autor:
Kelsey M. Pinckard, Elisa Félix-Soriano, Shanna Hamilton, Radmila Terentyeva, Lisa A. Baer, Katherine R. Wright, Drew Nassal, Joao Victor Esteves, Eaman Abay, Vikram K. Shettigar, Mark T. Ziolo, Thomas J. Hund, Loren E. Wold, Dmitry Terentyev, Kristin I. Stanford
Publikováno v:
Molecular Metabolism, Vol 82, Iss , Pp 101914- (2024)
Objective: The intrauterine environment during pregnancy is a critical factor in the development of obesity, diabetes, and cardiovascular disease in offspring. Maternal exercise prevents the detrimental effects of a maternal high fat diet on the meta
Externí odkaz:
https://doaj.org/article/43233158c48a4f618c81e1532dc8152a
Autor:
Eun-A Kwak, Christopher C. Pan, Aaron Ramonett, Sanjay Kumar, Paola Cruz-Flores, Tasmia Ahmed, Hannah R. Ortiz, Jeffrey J. Lochhead, Nathan A. Ellis, Ghassan Mouneimne, Teodora G. Georgieva, Yeon Sun Lee, Todd W. Vanderah, Tally Largent-Milnes, Peter J. Mohler, Thomas J. Hund, Paul R. Langlais, Karthikeyan Mythreye, Nam Y. Lee
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Defective angiogenesis remains a high source of morbidity in multiple disorders. Here they show that βIV-spectrin, a membrane-associated cytoskeletal protein, is essential for regulation of endothelial tip cell populations and VEGF signaling during
Externí odkaz:
https://doaj.org/article/9b6fe5a83d2b46eeafef20d5197ddbd4
Autor:
Louisa Mezache, Heather L. Struckman, Amara Greer-Short, Stephen Baine, Sándor Györke, Przemysław B. Radwański, Thomas J. Hund, Rengasayee Veeraraghavan
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Atrial fibrillation (AF) is the most common arrhythmia and is associated with inflammation. AF patients have elevated levels of inflammatory cytokines known to promote vascular leak, such as vascular endothelial growth factor A (VEGF). Howev
Externí odkaz:
https://doaj.org/article/339058eefeee476198027db5f79e00fe
Autor:
Crystal M. Ripplinger, Alexey V. Glukhov, Matthew W. Kay, Bastiaan J. Boukens, Nipavan Chiamvimonvat, Brian P. Delisle, Larissa Fabritz, Thomas J. Hund, Bjorn C. Knollmann, Na Li, Katherine T. Murray, Steven Poelzing, T. Alexander Quinn, Carol Ann Remme, Stacey L. Rentschler, Robert A. Rose, Nikki G. Posnack
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 323(6):H1137-H1166
Cardiac arrhythmias are a major cause of morbidity and mortality worldwide. Although recent advances in cell-based models, including human-induced pluripotent stem cell-derived cardiomyocytes (iPSC-CM), are contributing to our understanding of electr
Autor:
Tasmia Ahmed, Aaron Ramonett, Eun-A Kwak, Sanjay Kumar, Paola Cruz Flores, Hannah R. Ortiz, Paul R. Langlais, Thomas J. Hund, Karthikeyan Mythreye, Nam Y. Lee
Publikováno v:
Molecular Biology of the Cell. 34
The first transcriptional pathway regulating βIV-spectrin expression, a key angiogenic regulator of sprouting angiogenesis, is identified.
Autor:
Drew M. Nassal, Thomas J. Hund
Publikováno v:
Circulation Research. 131:1034-1036
Autor:
Narasimham L. Parinandi, Alex Liaugminas, Patrick J. Oliver, Saradhadevi Varadharaj, Anita Yenigalla, Austin C. Elliott, Sukruthi Arutla, Steven J. Campbell, Sainath R. Kotha, Shariq I. Sherwani, Vijay K. Kutala, Jodi C. McDaniel, Krishna Rao Maddipati, Periannan Kuppusamy, Thomas J. Hund
Publikováno v:
Cell Biochemistry and Biophysics.
Autor:
Przemysław B. Radwański, PharmD, PhD, Hsiang-Ting Ho, PhD, Rengasayee Veeraraghavan, PhD, Lucia Brunello, PhD, Bin Liu, PhD, Andriy E. Belevych, PhD, Sathya D. Unudurthi, PhD, Michael A. Makara, PhD, Silvia G. Priori, MD, PhD, Pompeo Volpe, PhD, Antonis A. Armoundas, PhD, Wolfgang H. Dillmann, MD, Bjorn C. Knollmann, MD, PhD, Peter J. Mohler, PhD, Thomas J. Hund, PhD, Sándor Györke, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 1, Iss 4, Pp 251-266 (2016)
Although triggered arrhythmias including catecholaminergic polymorphic ventricular tachycardia (CPVT) are often caused by increased levels of circulating catecholamines, the mechanistic link between β-adrenergic receptor (AR) stimulation and the sub
Externí odkaz:
https://doaj.org/article/14f969abcf034b40ad9a83088e11255d
Autor:
Gaurav Gupta, Sanjay Varikuti, Thomas J. Hund, Abhay R. Satoskar, Sainath R. Kotha, Andrew B. Shelton, Travis O. Gurney, Narasimham L. Parinandi, Nidhi Srivastava, A. Douglas Kinghorn, James R. Fuchs
Publikováno v:
Cell Biochemistry and Biophysics. 80:45-61
Our earlier in vitro and in vivo studies have revealed that the phytosterol, pentalinonsterol (cholest-4,20,24-trien-3-one) (PEN), isolated from the roots of Pentalinon andrieuxii, possesss immunomodulatory properties in macrophages and dendritic cel