Zobrazeno 1 - 10
of 738
pro vyhledávání: '"J. Hume"'
Autor:
Na Cui, Yael L. Perez, Adam J. Hume, B. Ethan Nunley, Kevin Kong, Margaret G. Mills, Hong Xie, Alexander L. Greninger
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 9 (2024)
ABSTRACT Filoviruses are some of the most lethal viruses in the modern world, and increasing numbers of filovirus species and genera have been discovered in recent years. Despite the potential severity of filovirus outbreaks in the human population,
Externí odkaz:
https://doaj.org/article/d3cff04db85d462bbde5c7b1805fda81
Autor:
Adam J. Hume, Dylan J. Deeney, John S. Smetana, Jacquelyn Turcinovic, John H. Connor, Marlene Belfort, Elke Mühlberger, Christopher W. Lennon
Publikováno v:
mBio, Vol 15, Iss 6 (2024)
ABSTRACT Intervening proteins (inteins) are translated as subdomains within host proteins and removed through an intein-driven splicing reaction where the flanking sequences (exteins) are joined with a peptide bond. Previously, we developed a self-re
Externí odkaz:
https://doaj.org/article/de4e8bdb72b6499c8d080224ab36e8e1
Publikováno v:
Pathogens, Vol 13, Iss 7, p 587 (2024)
Recent advances in high-throughput sequencing technologies have led to the discovery of a plethora of previously unknown viruses in animal samples. Some of these newly detected viruses are closely related to human pathogens. A prime example are the h
Externí odkaz:
https://doaj.org/article/2004691994f7484cb9586c78f7cedc34
Autor:
Stephen J. Ross, Adam J. Hume, Judith Olejnik, Jacquelyn Turcinovic, Anna N. Honko, Lindsay G. A. McKay, John H. Connor, Anthony Griffiths, Elke Mühlberger, Daniel Cifuentes
Publikováno v:
Viruses, Vol 16, Iss 7, p 1064 (2024)
Although next-generation sequencing (NGS) has been instrumental in determining the genomic sequences of emerging RNA viruses, de novo sequence determination often lacks sufficient coverage of the 5′ and 3′ ends of the viral genomes. Since the gen
Externí odkaz:
https://doaj.org/article/af4be9266d694121958cb9c7fd2df16f
Autor:
Gábor E. Tóth, Adam J. Hume, Ellen L. Suder, Safia Zeghbib, Ágota Ábrahám, Zsófia Lanszki, Zsaklin Varga, Zsófia Tauber, Fanni Földes, Brigitta Zana, Dino Scaravelli, Maria Teresa Scicluna, Andrea Pereswiet-Soltan, Tamás Görföl, Calogero Terregino, Paola De Benedictis, Isabel Garcia-Dorival, Covadonga Alonso, Ferenc Jakab, Elke Mühlberger, Stefania Leopardi, Gábor Kemenesi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Lloviu cuevavirus (LLOV) was the first identified member of Filoviridae family outside the Ebola and Marburgvirus genera. A massive die-off of Schreibers’s bats (Miniopterus schreibersii) in the Iberian Peninsula in 2002 led to its initial
Externí odkaz:
https://doaj.org/article/117063f0091e464294ee682425844fa2
Autor:
Robert J. Hume
Do US Supreme Court justices withdraw from cases when they are supposed to? What happens when the Court is down a member? In Ethics and Accountability on the US Supreme Court, Robert J. Hume provides the first comprehensive examination of the causes
Autor:
Adam J. Hume, Judith Olejnik, Mitchell R. White, Jessie Huang, Jacquelyn Turcinovic, Baylee Heiden, Pushpinder S. Bawa, Christopher J. Williams, Nickolas G. Gorham, Yuriy O. Alekseyev, John H. Connor, Darrell N. Kotton, Elke Mühlberger
Publikováno v:
Pathogens, Vol 13, Iss 1, p 62 (2024)
Single-cell RNA sequencing (scRNA-seq) technologies are instrumental to improving our understanding of virus–host interactions in cell culture infection studies and complex biological systems because they allow separating the transcriptional signat
Externí odkaz:
https://doaj.org/article/73c0987378d64d07b63bcbae717fefc9
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106643- (2023)
Summary: Salmonella Typhimurium drives uptake into non-phagocytic host cells by injecting effector proteins that reorganize the actin cytoskeleton. The host actin regulator N-WASP has been implicated in bacterial entry, but its precise role is not cl
Externí odkaz:
https://doaj.org/article/2704bfa5746547fdacec77505b70461c
Autor:
Gábor Kemenesi, Gábor E. Tóth, Martin Mayora-Neto, Simon Scott, Nigel Temperton, Edward Wright, Elke Mühlberger, Adam J. Hume, Ellen L. Suder, Brigitta Zana, Sándor A. Boldogh, Tamás Görföl, Péter Estók, Zsófia Lanszki, Balázs A. Somogyi, Ágnes Nagy, Csaba I. Pereszlényi, Gábor Dudás, Fanni Földes, Kornélia Kurucz, Mónika Madai, Safia Zeghbib, Piet Maes, Bert Vanmechelen, Ferenc Jakab
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Lloviu virus (LLOV) is a filovirus that was first identified in 2002 in Schreiber’s bats in Europe. Here, the authors isolate infectious LLOV from Schreiber’s bats in Hungary and show that it can infect human cells in vitro, suggesting potential
Externí odkaz:
https://doaj.org/article/32986f441a644d9ea1543b1895b295fd
Autor:
Judith Olejnik, Adam J. Hume, Stephen J. Ross, Whitney A. Scoon, Scott Seitz, Mitchell R. White, Ben Slutzky, Nadezhda E. Yun, Elke Mühlberger
Publikováno v:
Pathogens, Vol 12, Iss 7, p 952 (2023)
The study of highly pathogenic viruses handled under BSL-4 conditions and classified as Select Agents frequently involves the transfer of inactivated materials to lower containment levels for downstream analyses. Adhering to Select Agent and BSL-4 sa
Externí odkaz:
https://doaj.org/article/c26bcb4efaf34936bdb613d5b61dc334