Zobrazeno 1 - 10
of 71
pro vyhledávání: '"J. Howard Rytting"'
Publikováno v:
Journal of Pharmaceutical Sciences. 97:4194-4207
To enhance the physical stability of Clostridium difficile toxoids A and B, screening for stabilizing compounds was performed. The screening of 30 GRAS compounds at various concentrations and in several combinations was performed in two parts. First,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1800295986e9ef362c59901e167226
https://doi.org/10.1002/jps.21300
https://doi.org/10.1002/jps.21300
Autor:
Tom Offerdahl, J. Howard Rytting, Fei Tian, Eric J. Munson, C. Russell Middaugh, Samir U. Sane
Publikováno v:
International Journal of Pharmaceutics. 335:20-31
The protective effects of amino acids on stabilizing protein secondary structure were evaluated using diffuse reflectance FTIR spectroscopy, and interactions between proteins and arginine were detected using solid-state NMR spectroscopy. Upon freeze-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88318ca8cbc71ccc35d2751642ad5489
https://doi.org/10.1016/j.ijpharm.2006.10.037
https://doi.org/10.1016/j.ijpharm.2006.10.037
Publikováno v:
Journal of Inclusion Phenomena and Macrocyclic Chemistry. 44:93-96
The bioavailability parameters of a drug after oral administration of a preparation containing drug/CyD complexes may be modified by formation of competitive inclusion complexes. In this study, we examined the effects of competitors on drug permeatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d43ed2178c4d2ad61a153080af855d1
https://doi.org/10.1023/a:1023037016997
https://doi.org/10.1023/a:1023037016997
Autor:
Hitomi Sakano, Shiho Kuroda, Koichi Takahashi, Nobuyasu Mizuno, J. Howard Rytting, Nanako Numata
Publikováno v:
Drug Development and Industrial Pharmacy. 27:159-164
The influence of pH on the permeability of p-toluidine (pKa, 5.3) and aminopyrine (pKa, 5.0) through shed snake skin as a model membrane was studied. The pH was adjusted to several values, and the solubility of the drugs in each donor was measured. F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20eb820c86de7ceb3f891f4f2e35dce4
https://doi.org/10.1081/ddc-100000482
https://doi.org/10.1081/ddc-100000482
Autor:
Toshiaki Nishihata, J. Howard Rytting
Publikováno v:
Advanced Drug Delivery Reviews. 28:205-228
Studies of absorption-promoting adjuvants used for the modification of the barrier function of the rectal membrane are interesting for biochemical research as well as providing a basis for the development of new formulations of poorly absorbed drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6b8ed0406aa00e38951eea7a1712397
https://doi.org/10.1016/s0169-409x(97)00073-2
https://doi.org/10.1016/s0169-409x(97)00073-2
Autor:
J. Howard Rytting, Danchen Gao
Publikováno v:
International Journal of Pharmaceutics. 151:183-192
A solution calorimetry method was developed to quantitatively examine mixtures of amorphous and crystalline sucrose or warfarin sodium based on the energy differences between their solid forms. The heats of solution of crystalline sucrose, amorphous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2a8d84a659d7923f83c9c42f81618da
https://doi.org/10.1016/s0378-5173(97)04895-3
https://doi.org/10.1016/s0378-5173(97)04895-3
Autor:
J. Howard Rytting
Publikováno v:
FARMS Review of Books. 9:39-46
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e340819be119b443143588653b1c0d3a
https://doi.org/10.2307/44792759
https://doi.org/10.2307/44792759
Autor:
Arto Urtti, Lea Pirskanen, Mervi Raisanen, Kirsi Kosonen, Petteri Paronen, T. Marjukka Suhonen, J. Howard Rytting
Publikováno v:
Journal of Controlled Release. 43:251-259
The effect of the penetration enhancers Azone, 1-dodecanol, and dodecyl-2-(N,N-dimethylamino)propionate (DDAIP) on the structural integrity of liposomes composed of stratum corneum (SC) lipids was studied. With increasing enhancer concentration (0–
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebee2ffea109b50693efbc9daffc46a6
https://doi.org/10.1016/s0168-3659(96)01495-2
https://doi.org/10.1016/s0168-3659(96)01495-2
Publikováno v:
International Journal of Pharmaceutics. 118:113-119
1-(N,N-Dimethylamino)-2-propanol dodecanoate (DAIPD), a new biodegradable penetration enhancer was prepared by condensing lauroyl chloride with 1-(N,N-dimethylamino)-2-propanol. The penetration enhancing effects of DAIPD on the transdermal delivery o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27559d9041eb630d53a132ba61fb49a9
https://doi.org/10.1016/0378-5173(94)00359-d
https://doi.org/10.1016/0378-5173(94)00359-d
Publikováno v:
Journal of Controlled Release. 33:357-363
Syntheses of copolymers of methyl methacrylate (MMA) and 2-hydroxyethyl methacrylate (HEMA) were carried out in solution without the addition of external covalent crosslinkers. Devices were formulated as coated matrices: 80% (w/w) chlorhexidine diace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41e363c5c48bf8dbf4a8500be3a4fcf9
https://doi.org/10.1016/0168-3659(94)00104-3
https://doi.org/10.1016/0168-3659(94)00104-3