Zobrazeno 1 - 10
of 38
pro vyhledávání: '"J. Howard Pringle"'
Autor:
Tamihiro Kamata, Esraa Al Dujaily, Salwa Alhamad, Tsz Y. So, Olga Margaritaki, Susan Giblett, J. Howard Pringle, John Le Quesne, Catrin Pritchard
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 2 (2022)
Anti-cancer properties of statins are controversial and possibly context dependent. Recent pathology/epidemiology studies of human lung adenocarcinoma showed reduced pro-tumourigenic macrophages associated with a shift to lower-grade tumours amongst
Externí odkaz:
https://doaj.org/article/a59fd8397cbc4ea68a7af64800236bfe
Autor:
David S. Guttery, Rachael A. Hancox, Kellie T. Mulligan, Simon Hughes, Sinead M. Lambe, J. Howard Pringle, Rosemary A. Walker, J. Louise Jones, Jacqueline A. Shaw
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-1 (2018)
After the publication of this work [1] an error was noticed in Fig. 6 (b). In the MCF-7/Vector columns, the same image was used accidentally for the 0 h and 24 h time points. Both images were taken from the 0 h time point.
Externí odkaz:
https://doaj.org/article/a5d0dee01c1b48d2a333bc0f2dbc059d
Autor:
Marion MacFarlane, Lynne M. Howells, Catrin Pritchard, Gareth J Miles, J. Howard Pringle, Ian R. Powley, Seid Mohammed, Tim Hammonds
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
Patient Derived Explants (PDEs) represent the direct culture of fragments of freshly-resected tumour tissue under conditions that retain the original architecture of the tumour. PDEs have advantages over other preclinical cancer models as platforms f
Autor:
Marion MacFarlane, Gareth J Miles, Esther L. Moss, Ian R. Powley, Catrin Pritchard, Roger Hew, J. Howard Pringle, Anna Collins
Publikováno v:
Gynecologic Oncology. 160:557-567
Objective To undertake a pilot study to develop a novel Patient-Derived-Explant (PDE) model system for use in endometrial cancer (EC) that is capable of monitoring differential drug responses in a pre-clinical setting. Methods Fresh tumour was obtain
Autor:
Janella de Jesus, Catia Costa, Ellie Karekla, Calum J. Greenhalgh, Catrin Pritchard, Melanie J. Bailey, Marion MacFarlane, J. Howard Pringle, Amy J. Managh, Gareth J. Miles, Ian R. Powley
Publikováno v:
Analytical chemistry. 92(14)
The use of a low aerosol dispersion ablation chamber within a laser ablation inductively coupled plasma mass spectrometer (LA-ICP-MS) setup allows for high-resolution, high-speed imaging of the distribution of elements within a sample. Here we show h
Autor:
Kathryn P. Lawes, Kah Wee Teo, Farhaan Moosa, J. Howard Pringle, M. Bamford, Kushal Joshi, Gerald Saldanha
Outcomes for melanoma patients vary within cancer stage. Prognostic biomarkers are potential adjuncts to provide more precise prognostic information. Simple, low-cost biomarker assays, such as those based on immunohistochemistry, have strong translat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::773bb429364050891ddba23b3c1a5f69
https://europepmc.org/articles/PMC6176904/
https://europepmc.org/articles/PMC6176904/
Autor:
Joël Lachuer, Gina Tse, Gerald Saldanha, Anne Wierinckx, Stéphane Ansieau, Peter E. Hutchinson, Eftychios Papadogeorgakis, Eugene Tulchinsky, Alain Puisieux, J.E. Osborne, Louise Hill, Julie Caramel, Geoffrey Richard, Gareth J. Browne, J. Howard Pringle
Publikováno v:
Cancer Cell. 24:466-480
SummaryAberrant expression of embryonic epithelial-mesenchymal transition-inducing transcription factors (EMT-TFs) in epithelial cells triggers EMT, neoplastic transformation, stemness, and metastatic dissemination. We found that regulation and funct
Publikováno v:
Histopathology. 60:679-689
Prognostic tissue markers in melanoma Prognosis for patients diagnosed with cutaneous melanoma is currently based upon histopathological features alone, although tumours which are morphologically similar can behave differently. Numerous putative biom
Publikováno v:
Cancer and Metastasis Reviews. 29:595-606
Tenascin-C (TNC) is an extracellular matrix glycoprotein which is frequently up-regulated in a variety of pathological conditions including chronic inflammation and cancer. TNC has been implicated in the modulation of cell migration, proliferation, i
Autor:
J. Howard Pringle, Jacqueline A Shaw, Rosemary A. Walker, Rachael A. Hancox, Sinead M. Lambe, J. Louise Jones, David S. Guttery, Simon Hughes, Kellie T. Mulligan
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-1 (2018)
Breast Cancer Research : BCR
Breast Cancer Research : BCR
Introduction Tenascin-C (TNC) is a large extracellular matrix glycoprotein that shows prominent stromal expression in many solid tumours. The profile of isoforms expressed differs between cancers and normal breast, with the two additional domains AD1