Zobrazeno 1 - 10
of 2 400
pro vyhledávání: '"J. Houghton"'
Autor:
T. Waddell, K. Fife, R. Griffiths, A. Sharma, P. Dhokia, L. Groves, M. Hurst, C. Tsang, D. Sugrue, S. McKenna, J. Houghton, R. Carroll
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background The CheckMate 025 trial established nivolumab monotherapy as one of the standards of care in previously treated advanced or metastatic renal cell carcinoma (aRCC). However, supporting real-world data is lacking. This study investi
Externí odkaz:
https://doaj.org/article/43b59a58f81840d4b547be0feca7bc8a
Publikováno v:
Skin Health and Disease, Vol 1, Iss 3, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/90e7e49b40d14dacb150fde8d1c84bd3
Autor:
S. Fishbane, R. Provenzano, P. Pergola, L. Szczech, R. Leong, K. Saikali, M. Zhong, T. Lee, D. Little, M. Houser, L. Frison, J. Houghton, K.H.P. Yu
Publikováno v:
Kidney International Reports, Vol 6, Iss 4, Pp S109-S110 (2021)
Externí odkaz:
https://doaj.org/article/3428a175e24049b9a527897cb4897f7f
Autor:
R. Provenzano, S. Fishbane, P. Pergola, L. Szczech, R. Leong, K. Saikali, M. Zhong, T. Lee, M. Houser, D. Little, L. Frison, J. Houghton, K.H.P. Yu
Publikováno v:
Kidney International Reports, Vol 6, Iss 4, Pp S121- (2021)
Externí odkaz:
https://doaj.org/article/e91621367ac2415396eed97352260bbf
Autor:
R. Savova, M. Arshinkova, J. Houghton, M. Konstantinova, M. Gaydarova, E. Georgieva, G. Popova, V. Genova, N. Tomova, A. Anadoliiska, K. Koprivarova
Publikováno v:
Case Reports in Medicine, Vol 2014 (2014)
Objective. To describe the clinical characteristics of IPEX syndrome in a child with FOXP3 mutation. Clinical Case. A boy aged 2.3 years was born from first normal pregnancy with a weight of 3420 gr. Family History. Two brothers of the mother died be
Externí odkaz:
https://doaj.org/article/393eb008482f48a4a453675aef2215ca
Autor:
Peter J Houghton
Publikováno v:
Open Access Government. 38:88-91
Exploring current and future therapies for childhood astrocytoma Here, Doctor Peter J Houghton explains current therapies for childhood brain cancer what needs to change to ensure better outcomes for children diagnosed with astrocytoma in the future.
Autor:
Terry J. Shackleford, Seethalakshmi Hariharan, Angelina V. Vaseva, Karina Alagoa, Maricruz Espinoza, Hemant K. Bid, Fuyang Li, Haihong Zhong, Doris A. Phelps, Ryan D. Roberts, Hakan Cam, Cheryl A. London, Denis C. Guttridge, Yidong Chen, Manjeet Rao, Yuzuru Shiio, Peter J. Houghton
Publikováno v:
Molecular Cancer Therapeutics. 22:539-550
Antibodies targeting insulin-like growth factor 1 receptor (IGF-1R) induce objective responses in only 5% to 15% of children with sarcoma. Understanding the mechanisms of resistance may identify combination therapies that optimize efficacy of IGF-1R
Publikováno v:
Memory & Cognition. 51:825-844
Autor:
Stefan Tucker, Christopher J. Houghton, Brandon Harris, Robert Elliott, Michael Donofrio, Patrick S. Forsythe
Publikováno v:
Transactions of the American Fisheries Society. 151:682-694
Autor:
Stanley C. Xie, Riley D. Metcalfe, Elyse Dunn, Craig J. Morton, Shih-Chung Huang, Tanya Puhalovich, Yawei Du, Sergio Wittlin, Shuai Nie, Madeline R. Luth, Liting Ma, Mi-Sook Kim, Charisse Flerida A. Pasaje, Krittikorn Kumpornsin, Carlo Giannangelo, Fiona J. Houghton, Alisje Churchyard, Mufuliat T. Famodimu, Daniel C. Barry, David L. Gillett, Sumanta Dey, Clara C. Kosasih, William Newman, Jacquin C. Niles, Marcus C. S. Lee, Jake Baum, Sabine Ottilie, Elizabeth A. Winzeler, Darren J. Creek, Nicholas Williamson, Michael W. Parker, Stephen Brand, Steven P. Langston, Lawrence R. Dick, Michael D.W. Griffin, Alexandra E. Gould, Leann Tilley
Publikováno v:
Science. 376:1074-1079
Aminoacyl transfer RNA (tRNA) synthetases (aaRSs) are attractive drug targets, and we present class I and II aaRSs as previously unrecognized targets for adenosine 5′-monophosphate–mimicking nucleoside sulfamates. The target enzyme catalyzes the